sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bej | MUF | Bile acid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3bej | MUF | Bile acid receptor | / | 1.000 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.488 | |
| 2acw | UPG | Glycosyltransferase | / | 0.476 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.473 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.471 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.468 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.467 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.463 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.463 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.462 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.462 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 3up3 | XCA | aceDAF-12 | / | 0.460 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.459 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.459 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.458 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.458 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.457 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.457 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.456 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.455 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.453 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.453 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.453 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.453 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.452 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.452 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.452 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 1osv | CHC | Bile acid receptor | / | 0.449 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.449 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.449 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.449 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.449 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.447 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.447 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.446 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.446 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.446 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.445 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.445 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.444 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.443 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.443 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.443 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.442 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.441 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.441 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.440 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 |