sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bbp | GTP | Ras-related protein Rab-6A |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3bbp | GTP | Ras-related protein Rab-6A | / | 1.000 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.628 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.599 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.585 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.578 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.575 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.573 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.564 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.561 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.558 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.537 | |
| 3lbn | GNP | GTPase HRas | / | 0.524 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.523 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.513 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.507 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.496 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.495 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.492 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.489 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.488 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.488 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.487 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.483 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.477 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.477 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.475 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.474 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.469 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.467 | |
| 3oiv | GNP | GTPase HRas | / | 0.467 | |
| 3v4f | GNP | GTPase HRas | / | 0.467 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.463 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.460 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.459 | |
| 3ddc | GNP | GTPase HRas | / | 0.457 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.456 | |
| 5b2z | GNP | GTPase HRas | / | 0.456 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.454 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.453 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.453 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.451 | |
| 3oiu | GNP | GTPase HRas | / | 0.451 | |
| 4nyi | GNP | GTPase HRas | / | 0.451 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.450 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.450 | |
| 3rs5 | GNP | GTPase HRas | / | 0.450 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.448 | |
| 2rge | GNP | GTPase HRas | / | 0.445 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.444 | |
| 4dlt | GNP | GTPase HRas | / | 0.444 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.444 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.443 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.443 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.442 | |
| 4nyj | GNP | GTPase HRas | / | 0.442 | |
| 2c5l | GTP | GTPase HRas | / | 0.441 |