sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3b1j | NAD | Glyceraldehyde-3-phosphate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3b1j | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 1.000 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.468 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.449 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.441 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 |