sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 1.000 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.992 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.661 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.633 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.628 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.609 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.607 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.603 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.577 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.530 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.504 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.446 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 |