Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3autNAIGlucose 1-dehydrogenase 41.1.1.47

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3autNAIGlucose 1-dehydrogenase 41.1.1.471.000
1gcoNADGlucose 1-dehydrogenase1.1.1.470.609
1geeNADGlucose 1-dehydrogenase1.1.1.470.607
1g6kNADGlucose 1-dehydrogenase1.1.1.470.602
1rwbNADGlucose 1-dehydrogenase1.1.1.470.584
4gh5NADShort-chain dehydrogenase/reductase SDR/0.482
4hwkNAPSepiapterin reductase1.1.1.1530.481
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.480
2dteNAIGlucose 1-dehydrogenase related protein/0.477
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.477
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.476
4j7xNAPSepiapterin reductase1.1.1.1530.472
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.468
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.468
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.467
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.465
4hxyNDPPlm1/0.465
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.464
5jlaNADPutative short-chain dehydrogenase/reductase/0.463
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.462
3toxNAPPutative oxidoreductase/0.460
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1x7gNAPPutative ketoacyl reductase1.3.10.459
4kwhNAPReductase homolog/0.454
5jydNADShort chain dehydrogenase/0.454
1w4zNAPPutative ketoacyl reductase1.3.10.451
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.450
2c29NAPDihydroflavonol 4-reductase/0.447
5idwNAPShort-chain dehydrogenase/reductase SDR/0.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4dc0NDPPutative ketoacyl reductase1.3.10.445
3s55NADPutative short-chain dehydrogenase/reductase/0.443
4j7uNAPSepiapterin reductase1.1.1.1530.443
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.442
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.442
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.442
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.441
2bd0NAPSepiapterin reductase/0.440
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.440