sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3atz	FMN	Prostaglandin F2a synthase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3atz	FMN	Prostaglandin F2a synthase	/	1.000
4e2d	FMN	Dehydrogenase	/	0.627
3aty	FMN	Prostaglandin F2a synthase	/	0.605
4e2b	FMN	Dehydrogenase	/	0.550
4jic	FMN	GTN Reductase	/	0.484
1h50	FMN	Pentaerythritol tetranitrate reductase	/	0.459
4a3u	FMN	NADH:flavin oxidoreductase/NADH oxidase	/	0.456
1h63	FMN	Pentaerythritol tetranitrate reductase	/	0.445
2abb	FMN	Pentaerythritol tetranitrate reductase	/	0.444
1vyr	FMN	Pentaerythritol tetranitrate reductase	/	0.441
3p74	FMN	Pentaerythritol tetranitrate reductase	/	0.440
3p82	FMN	Pentaerythritol tetranitrate reductase	/	0.440