sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 1.000 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.604 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.476 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.468 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.467 | |
| 3sju | NDP | Keto reductase | / | 0.463 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.455 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.454 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.451 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.450 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 |