Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3a58GNPGTP-binding protein RHO1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3a58GNPGTP-binding protein RHO1/1.000
1cxzGSPTransforming protein RhoA/0.569
1kmqGNPTransforming protein RhoA/0.557
1g17GNPRas-related protein SEC4/0.552
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.546
2gcpGSPRho-related GTP-binding protein RhoC/0.542
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.542
3kz1GSPTransforming protein RhoA/0.540
3w3zGTPGTP-binding nuclear protein Ran/0.540
1a2bGSPTransforming protein RhoA/0.539
1yzqGNPRas-related protein Rab-6A/0.537
3e5hGNPRas-related protein Rab-28/0.535
4mitGTPRho-related protein racC/0.535
1e96GTPRas-related C3 botulinum toxin substrate 1/0.531
3eg5GNPCell division control protein 42 homolog/0.531
2clsGTPRho-related GTP-binding protein Rho6/0.528
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.524
3a6pGTPGTP-binding nuclear protein Ran/0.524
5dhaGNPGTP-binding nuclear protein Ran/0.524
1s1cGNPTransforming protein RhoA/0.523
1zbdGTPRas-related protein Rab-3A/0.521
1xtsGTPGTP-binding protein Rheb/0.519
3nbzGTPGTP-binding nuclear protein Ran/0.519
1m7bGTPRho-related GTP-binding protein RhoE/0.518
3oesGNPGTPase RhebL1/0.514
1t91GTPRas-related protein Rab-7a/0.513
3bbpGTPRas-related protein Rab-6A/0.513
4nyjGNPGTPase HRas/0.513
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.511
4nyiGNPGTPase HRas/0.507
1yhnGTPRas-related protein Rab-7a/0.503
4js0GNPCell division control protein 42 homolog/0.503
3i3sGNPGTPase HRas/0.497
3v4fGNPGTPase HRas/0.497
1z2cGNPRho-related GTP-binding protein RhoC/0.496
2gilGTPRas-related protein Rab-6A/0.496
4dltGNPGTPase HRas/0.494
4kvgGTPRas-related protein Rap-1A/0.494
3kucGDPRas-related protein Rap-1A/0.492
3lbnGNPGTPase HRas/0.492
4xoiGTPTransforming protein RhoA/0.492
3oivGNPGTPase HRas/0.490
3ddcGNPGTPase HRas/0.487
1zc4GNPRas-related protein Ral-A/0.485
4gzlGNPRas-related C3 botulinum toxin substrate 1/0.484
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.483
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.482
4cymGCPRas-related protein Rab-32/0.481
3oiuGNPGTPase HRas/0.480
1xtrGNPGTP-binding protein Rheb/0.479
1zc3GNPRas-related protein Ral-A/0.479
4dsoGSPGTPase KRas/0.479
3rs7GNPGTPase HRas/0.478
4ol0GTPGTP-binding nuclear protein Ran/0.478
5hpyGDPTransforming protein RhoA/0.478
1ibrGNPGTP-binding nuclear protein Ran/0.477
2zetGTPRas-related protein Rab-27B/0.476
2bkuGTPGTP-binding nuclear protein Ran/0.474
2ffqGSPRas-related protein Rab-6B/0.474
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.472
5b2zGNPGTPase HRas/0.472
3th5GNPRas-related C3 botulinum toxin substrate 1/0.470
3tnfGNPRas-related protein Rab-8A/0.469
1vg8GNPRas-related protein Rab-7a/0.468
2c5lGTPGTPase HRas/0.467
3tklGTPRas-related protein Rab-1A/0.467
3l8yGNPGTPase HRas/0.465
1ow3GDPTransforming protein RhoA/0.464
4rkfGNPRas-related protein Rab-3/0.464
4dlwGNPGTPase HRas/0.463
4gzmGSPRas-related C3 botulinum toxin substrate 1/0.461
1gwnGTPRho-related GTP-binding protein RhoE/0.458
4hdoGNPRas-related protein Rap-1b/0.458
4o25GTPGTP-binding protein Rheb/0.457
3lbiGNPGTPase HRas/0.456
2fe4GDPRas-related protein Rab-6B/0.454
3ea5GDPGTP-binding nuclear protein Ran/0.454
3lbhGNPGTPase HRas/0.453
2rgbGNPGTPase HRas/0.452
3rabGNPRas-related protein Rab-3A/0.452
3kkoGNPRas-related protein M-Ras/0.451
4g0nGNPGTPase HRas/0.451
3rs4GNPGTPase HRas/0.449
4dsnGCPGTPase KRas/0.449
2rgeGNPGTPase HRas/0.448
4lhwGNPRas-related protein Rab-8A/0.447
5jljGNPGTP-binding nuclear protein Ran/0.445
3bc1GNPRas-related protein Rab-27A/0.443
3rs5GNPGTPase HRas/0.442
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.441