sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2zrz	FNR	Isopentenyl-diphosphate delta-isomerase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2zrz	FNR	Isopentenyl-diphosphate delta-isomerase	/	1.000
2zrx	FMN	Isopentenyl-diphosphate delta-isomerase	/	0.613
3b04	OOP	Isopentenyl-diphosphate delta-isomerase	/	0.602
3b05	IPE	Isopentenyl-diphosphate delta-isomerase	/	0.588
3b03	VNR	Isopentenyl-diphosphate delta-isomerase	/	0.587
3b05	FNR	Isopentenyl-diphosphate delta-isomerase	/	0.584
2zrv	FNR	Isopentenyl-diphosphate delta-isomerase	/	0.560
2zry	FNR	Isopentenyl-diphosphate delta-isomerase	/	0.534
3vkj	FNR	Isopentenyl-diphosphate delta-isomerase	/	0.534
2zru	FMN	Isopentenyl-diphosphate delta-isomerase	/	0.509