sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 | 1.000 | |
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 0.637 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.594 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.566 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.562 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.558 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.553 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.550 | |
| 1wv7 | 5PI | Coagulation factor VII | 3.4.21.21 | 0.547 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.547 | |
| 1wtg | 3BP | Coagulation factor VII | 3.4.21.21 | 0.546 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.544 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.542 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.541 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.540 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.539 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.539 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.537 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.537 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.536 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.534 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.534 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.531 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.530 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.529 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.529 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.529 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.527 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.527 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.526 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.526 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.526 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.522 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.521 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.521 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.520 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.518 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.518 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.518 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.518 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.518 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.517 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.517 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.515 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.515 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.514 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.513 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.511 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.511 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.511 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.510 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.509 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.507 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.507 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.507 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.504 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.504 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.503 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.503 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.503 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.502 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.501 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.500 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.499 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.499 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.499 | |
| 1cgz | STL | Chalcone synthase 2 | 2.3.1.74 | 0.497 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.497 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.496 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.496 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.495 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.495 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.494 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.494 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.494 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.494 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.493 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.492 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.488 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.488 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.488 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.488 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.488 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.487 | |
| 2xbx | RR8 | Coagulation factor X | 3.4.21.6 | 0.487 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.486 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.486 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.486 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.485 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.485 | |
| 1yli | COA | Uncharacterized acyl-CoA thioester hydrolase HI_0827 | 3.1.2 | 0.483 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.483 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.482 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.482 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.482 | |
| 4mcd | 22L | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.482 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.481 | |
| 1l2o | ADP | Myosin heavy chain, striated muscle | / | 0.481 | |
| 1l4l | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.481 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.481 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.481 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.480 | |
| 4el0 | D1K | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.480 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.479 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.479 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.479 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.479 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.479 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.478 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.478 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.478 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.478 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.477 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.477 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.477 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.476 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.476 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.475 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.475 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.475 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.474 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.474 | |
| 2xc5 | OYJ | Coagulation factor X | 3.4.21.6 | 0.474 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.473 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.473 | |
| 3v49 | PK0 | Androgen receptor | / | 0.473 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.473 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.473 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.472 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.471 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.471 | |
| 1u6q | 745 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.471 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.471 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1jha | AAM | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.470 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.470 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.470 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.470 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.470 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.470 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.470 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.470 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.469 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.469 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.469 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.469 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.468 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.468 | |
| 3awh | FMN | FMN-binding protein | / | 0.468 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.468 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.468 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.467 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.467 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.467 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.467 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.467 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.467 | |
| 4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.467 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.467 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.466 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.466 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.466 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.466 | |
| 3kfp | 3TL | Gag-Pol polyprotein | / | 0.466 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.466 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.466 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.466 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.465 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.465 | |
| 1qy5 | NEC | Endoplasmin | / | 0.465 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 2wbb | RO3 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.465 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.465 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.465 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.465 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.465 | |
| 4ig6 | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.465 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.465 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.464 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.464 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.464 | |
| 3a6q | FMN | FMN-binding protein | / | 0.464 | |
| 3kqb | LGJ | Coagulation factor X | 3.4.21.6 | 0.464 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.463 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.463 | |
| 3a20 | FMN | FMN-binding protein | / | 0.463 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.463 | |
| 4lwp | SAH | Arginine N-methyltransferase, putative | / | 0.463 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.463 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.463 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.462 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.462 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.462 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.462 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.462 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.462 | |
| 3w2j | QRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.462 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4nyw | 2O3 | CREB-binding protein | / | 0.462 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.461 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.461 | |
| 1orh | SAH | Protein arginine N-methyltransferase 1 | / | 0.461 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.461 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.461 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.461 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.461 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.461 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.461 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.460 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.460 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.460 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.460 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.460 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.460 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.460 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.460 | |
| 4e2b | FMN | Dehydrogenase | / | 0.460 | |
| 4nvk | 2NY | Peroxidase | / | 0.460 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.459 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.459 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.459 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.459 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.459 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.458 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.458 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1l5l | 7RP | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.458 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.458 | |
| 2eeq | SAH | Diphthine synthase | / | 0.458 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.458 | |
| 2pca | SAH | Diphthine synthase | / | 0.458 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.458 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.458 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.458 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.458 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.458 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.457 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2p5c | SAH | Diphthine synthase | / | 0.457 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.457 | |
| 3b9l | AZZ | Serum albumin | / | 0.457 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.457 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 4dmg | SAM | Uncharacterized protein | / | 0.457 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.456 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.456 | |
| 2p2j | PRX | Acetyl-coenzyme A synthetase | / | 0.456 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.456 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.456 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.456 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.456 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 4db1 | ANP | Myosin-7 | / | 0.456 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.456 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.455 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.455 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.455 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.455 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.455 | |
| 2p6k | SAH | Diphthine synthase | / | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.455 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.455 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.454 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.454 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.454 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2bxq | IMN | Serum albumin | / | 0.454 | |
| 2dsh | SAH | Diphthine synthase | / | 0.454 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.454 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.454 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.454 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.454 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.453 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.453 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.453 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 2bxm | IMN | Serum albumin | / | 0.453 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.453 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.453 | |
| 2wbd | RO5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.453 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.453 | |
| 4x3l | MTA | RNA 2'-O ribose methyltransferase | / | 0.453 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.453 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.452 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1uam | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.452 | |
| 1upj | U01 | Gag-Pol polyprotein | / | 0.452 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.452 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2h2j | SFG | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.452 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.452 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.452 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.452 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.452 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.452 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.452 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.452 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.452 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.452 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.451 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2xvq | 9DS | Serum albumin | / | 0.451 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.451 | |
| 3sor | O58 | Coagulation factor XI | 3.4.21.27 | 0.451 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.451 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.451 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.451 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.451 | |
| 4kqg | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.451 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.451 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.450 | |
| 1fmw | ATP | Myosin-2 heavy chain | / | 0.450 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.450 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1l5o | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.450 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.450 | |
| 2ele | SAH | Diphthine synthase | / | 0.450 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2vwh | NAP | Glucose 1-dehydrogenase | / | 0.450 | |
| 3a6r | FMN | FMN-binding protein | / | 0.450 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 3gdv | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.450 | |
| 3gol | XND | Genome polyprotein | 2.7.7.48 | 0.450 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.450 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.450 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.450 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.450 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.450 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.449 | |
| 1l5k | 1RB | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.449 | |
| 1p9p | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.449 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.449 | |
| 3amt | ATP | tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS | 6.3.4.22 | 0.449 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.449 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.449 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.449 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.448 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.448 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.448 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.448 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2en5 | SAH | Diphthine synthase | / | 0.448 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.448 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.448 | |
| 4pzk | SAH | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.448 | |
| 1aku | FMN | Flavodoxin | / | 0.447 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.447 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.447 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.447 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.447 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2ohv | NHL | Glutamate racemase | / | 0.447 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.447 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.447 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.447 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.447 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.447 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.447 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.446 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.446 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2xvv | 9DN | Serum albumin | / | 0.446 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.446 | |
| 3bnk | FMN | Flavoredoxin | / | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.446 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.446 | |
| 3sfd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.446 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.446 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.446 | |
| 4app | N53 | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.446 | |
| 4cfc | 7NV | Integrase | / | 0.446 | |
| 4e2d | FMN | Dehydrogenase | / | 0.446 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.446 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.445 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.445 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.445 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.445 | |
| 2bxa | C1F | Serum albumin | / | 0.445 | |
| 2c4i | BTN | Avidin | / | 0.445 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.445 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2xby | 63C | Coagulation factor X | 3.4.21.6 | 0.445 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.445 | |
| 3eks | CY9 | Actin-5C | / | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.445 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.445 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4blr | UTP | NTPase P4 | / | 0.445 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.445 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.445 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.445 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.444 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.444 | |
| 1wng | SAH | Diphthine synthase | / | 0.444 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.444 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ccu | 2D9 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2eni | SAH | Diphthine synthase | / | 0.444 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.444 | |
| 2j5b | TYE | Tyrosine--tRNA ligase | 6.1.1.1 | 0.444 | |
| 2p2x | SAH | Diphthine synthase | / | 0.444 | |
| 2yi7 | BZ8 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.444 | |
| 3k8t | 2A5 | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.444 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3plp | BBA | Cationic trypsin | 3.4.21.4 | 0.444 | |
| 4boe | CLR | Japanin | / | 0.444 | |
| 4cif | JDX | Integrase | / | 0.444 | |
| 4fak | SAM | Ribosomal RNA large subunit methyltransferase H | / | 0.444 | |
| 4h4e | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.444 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.444 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.443 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.443 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.443 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3anx | MTA | Polyamine aminopropyltransferase | / | 0.443 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.443 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.443 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.443 | |
| 4bmp | FMN | Protein NrdI | / | 0.443 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.443 | |
| 4l16 | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.443 | |
| 4lhv | GDP | Ras-related protein Rab-8A | / | 0.443 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.443 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.443 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.443 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.443 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.442 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.442 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.442 | |
| 2huv | SAH | Diphthine synthase | / | 0.442 | |
| 2owu | SAH | Diphthine synthase | / | 0.442 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.442 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.442 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.442 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.442 | |
| 3nz4 | TCA | Phenylalanine aminomutase (L-beta-phenylalanine forming) | / | 0.442 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.442 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.442 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.442 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.442 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.442 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.441 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.441 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2dsi | SAH | Diphthine synthase | / | 0.441 | |
| 2e83 | FMN | FMN-binding protein | / | 0.441 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 2p9d | SAH | Diphthine synthase | / | 0.441 | |
| 2pck | SAH | Diphthine synthase | / | 0.441 | |
| 2r3a | SAM | Histone-lysine N-methyltransferase SUV39H2 | 2.1.1.43 | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.441 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.441 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.441 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.441 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 3v4a | PK1 | Androgen receptor | / | 0.441 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.441 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.441 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.441 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.441 | |
| 4mpc | PV2 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.441 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.441 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.441 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.441 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.441 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 1hk1 | T44 | Serum albumin | / | 0.440 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.440 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.440 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.440 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.440 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 3am3 | TCL | Enoyl-ACP reductase | / | 0.440 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.440 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.440 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.440 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.440 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.440 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3rnn | RNN | Glutamate receptor 2 | / | 0.440 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.440 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.440 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.440 | |
| 4gpj | 0Q1 | Bromodomain-containing protein 4 | / | 0.440 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.440 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4xcz | FON | Qdtf | / | 0.440 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 | |
| 5fsy | AR6 | Uncharacterized protein | / | 0.440 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.440 |