sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2znp	K55	Peroxisome proliferator-activated receptor delta

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2znp	K55	Peroxisome proliferator-activated receptor delta	/	1.000
2znq	401	Peroxisome proliferator-activated receptor delta	/	0.619
1k7l	544	Peroxisome proliferator-activated receptor alpha	/	0.562
1y0s	331	Peroxisome proliferator-activated receptor delta	/	0.555
3sp9	IL2	Peroxisome proliferator-activated receptor delta	/	0.544
2znn	S44	Peroxisome proliferator-activated receptor alpha	/	0.543
1i7g	AZ2	Peroxisome proliferator-activated receptor alpha	/	0.542
3sp6	IL2	Peroxisome proliferator-activated receptor alpha	/	0.525
2j14	GNI	Peroxisome proliferator-activated receptor delta	/	0.503
2npa	MMB	Peroxisome proliferator-activated receptor alpha	/	0.486
2q5g	1FA	Peroxisome proliferator-activated receptor delta	/	0.485
2om9	AJA	Peroxisome proliferator-activated receptor gamma	/	0.463
4f9m	FCM	Peroxisome proliferator-activated receptor gamma	/	0.456
3vso	EK1	Peroxisome proliferator-activated receptor gamma	/	0.453
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.449
4xuh	SFI	Peroxisome proliferator-activated receptor gamma	/	0.449
2q8s	L92	Peroxisome proliferator-activated receptor gamma	/	0.444
3v9y	24L	Peroxisome proliferator-activated receptor gamma	/	0.442
4hee	14R	Peroxisome proliferator-activated receptor gamma	/	0.441