sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2zev	B71	Geranylgeranyl pyrophosphate synthase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2zev	B71	Geranylgeranyl pyrophosphate synthase	/	1.000
2e94	364	Geranylgeranyl pyrophosphate synthase	/	0.563
2e8u	IPE	Geranylgeranyl pyrophosphate synthase	/	0.510
2z78	H86	Geranylgeranyl pyrophosphate synthase	/	0.491
2z4y	252	Geranylgeranyl pyrophosphate synthase	/	0.477
2z7h	GG3	Geranylgeranyl pyrophosphate synthase	/	0.463
2z4z	SC0	Geranylgeranyl pyrophosphate synthase	/	0.459
2z4w	749	Geranylgeranyl pyrophosphate synthase	/	0.449
2qd4	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.444