sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2zet	GTP	Ras-related protein Rab-27B

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2zet	GTP	Ras-related protein Rab-27B	/	1.000
3bc1	GNP	Ras-related protein Rab-27A	/	0.533
3tso	GNP	Ras-related protein Rab-25	/	0.500
4cym	GCP	Ras-related protein Rab-32	/	0.499
3rab	GNP	Ras-related protein Rab-3A	/	0.494
3e5h	GNP	Ras-related protein Rab-28	/	0.489
2gil	GTP	Ras-related protein Rab-6A	/	0.483
4lhw	GNP	Ras-related protein Rab-8A	/	0.480
5dha	GNP	GTP-binding nuclear protein Ran	/	0.457
3tnf	GNP	Ras-related protein Rab-8A	/	0.453
1ibr	GNP	GTP-binding nuclear protein Ran	/	0.452
1xtr	GNP	GTP-binding protein Rheb	/	0.441
3tkl	GTP	Ras-related protein Rab-1A	/	0.441
3oes	GNP	GTPase RhebL1	/	0.440