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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.184

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1841.000
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.504
1w4zNAPPutative ketoacyl reductase1.3.10.482
3qrwNDPPutative ketoacyl reductase1.3.10.474
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
1x7gNAPPutative ketoacyl reductase1.3.10.464
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
1x7hNDPPutative ketoacyl reductase1.3.10.450
4dc1NDPPutative ketoacyl reductase1.3.10.449
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3toxNAPPutative oxidoreductase/0.445
1wntNAPL-xylulose reductase1.1.1.100.444
1xkqNDPUncharacterized protein/0.443