sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2z6u	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2z6u	SAH	Modification methylase HhaI	2.1.1.37	1.000
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.686
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.586
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.568
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.563
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.549
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.546
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.538
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.538
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.516
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.515
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.504
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.496
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.492
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.476