sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yut | NAP | Putative short-chain oxidoreductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2yut | NAP | Putative short-chain oxidoreductase | / | 1.000 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.483 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.474 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.464 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.458 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.455 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.450 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.442 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 |