sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xxy | KAI | Glutamate receptor ionotropic, kainate 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xxy | KAI | Glutamate receptor ionotropic, kainate 2 | / | 1.000 | |
| 4bdo | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.591 | |
| 4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.578 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.550 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.547 | |
| 2xxv | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.543 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.529 | |
| 4h8i | 11W | Glutamate receptor ionotropic, kainate 2 | / | 0.520 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.503 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.501 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.492 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.485 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.467 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.463 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.450 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.447 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 |