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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2xmyCDKCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2xmyCDKCyclin-dependent kinase 22.7.11.221.000
3qtxX43Cyclin-dependent kinase 22.7.11.220.624
4fko20KCyclin-dependent kinase 22.7.11.220.594
3qu0X40Cyclin-dependent kinase 22.7.11.220.572
3rpv26ZCyclin-dependent kinase 22.7.11.220.571
4acm7YGCyclin-dependent kinase 22.7.11.220.561
3lfnA27Cyclin-dependent kinase 22.7.11.220.559
1ke5LS1Cyclin-dependent kinase 22.7.11.220.558
2r3jSCJCyclin-dependent kinase 22.7.11.220.554
1y91CT9Cyclin-dependent kinase 22.7.11.220.553
1ykr628Cyclin-dependent kinase 22.7.11.220.552
4ek816KCyclin-dependent kinase 22.7.11.220.552
3rk708ZCyclin-dependent kinase 22.7.11.220.550
4fkt48KCyclin-dependent kinase 22.7.11.220.550
4fks46KCyclin-dependent kinase 22.7.11.220.548
4fkq42KCyclin-dependent kinase 22.7.11.220.546
1pxmCK5Cyclin-dependent kinase 22.7.11.220.543
2uzoC62Cyclin-dependent kinase 22.7.11.220.541
3py0SU9Cyclin-dependent kinase 22.7.11.220.539
1ckpPVBCyclin-dependent kinase 22.7.11.220.536
4fkv61KCyclin-dependent kinase 22.7.11.220.534
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.533
3rmf20ZCyclin-dependent kinase 22.7.11.220.533
3s1h56ZCyclin-dependent kinase 22.7.11.220.533
2a4lRRCCyclin-dependent kinase 22.7.11.220.531
1pxlCK4Cyclin-dependent kinase 22.7.11.220.530
3rak03ZCyclin-dependent kinase 22.7.11.220.530
3r8lZ30Cyclin-dependent kinase 22.7.11.220.529
2a0cCK9Cyclin-dependent kinase 22.7.11.220.527
3qtuX44Cyclin-dependent kinase 22.7.11.220.527
1g5sI17Cyclin-dependent kinase 22.7.11.220.525
3qzgX67Cyclin-dependent kinase 22.7.11.220.522
3sw418KCyclin-dependent kinase 22.7.11.220.522
4ek610KCyclin-dependent kinase 22.7.11.220.519
1oirHDYCyclin-dependent kinase 22.7.11.220.518
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.518
3rk909ZCyclin-dependent kinase 22.7.11.220.518
3r1yX76Cyclin-dependent kinase 22.7.11.220.517
2c6o4SPCyclin-dependent kinase 22.7.11.220.516
1gih1PUCyclin-dependent kinase 22.7.11.220.515
3qwjX6ACyclin-dependent kinase 22.7.11.220.514
3lfqA28Cyclin-dependent kinase 22.7.11.220.513
4bgh3I6Cyclin-dependent kinase 22.7.11.220.512
4fki09KCyclin-dependent kinase 22.7.11.220.511
4fkpLS5Cyclin-dependent kinase 22.7.11.220.510
2b52D42Cyclin-dependent kinase 22.7.11.220.509
3rni21ZCyclin-dependent kinase 22.7.11.220.508
4fkg4CKCyclin-dependent kinase 22.7.11.220.508
1pxoCK7Cyclin-dependent kinase 22.7.11.220.504
2btsU32Cyclin-dependent kinase 22.7.11.220.504
3ezvEZVCyclin-dependent kinase 22.7.11.220.504
2bheBRYCyclin-dependent kinase 22.7.11.220.503
1y8yCT7Cyclin-dependent kinase 22.7.11.220.502
2btrU73Cyclin-dependent kinase 22.7.11.220.502
2w1hL0FCyclin-dependent kinase 22.7.11.220.501
3r8vZ62Cyclin-dependent kinase 22.7.11.220.501
3sw719KCyclin-dependent kinase 22.7.11.220.501
3unk0BYCyclin-dependent kinase 22.7.11.220.499
3iggEFQCyclin-dependent kinase 22.7.11.220.498
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.497
3qtrX36Cyclin-dependent kinase 22.7.11.220.497
3qtzX42Cyclin-dependent kinase 22.7.11.220.497
3rjc06ZCyclin-dependent kinase 22.7.11.220.497
2xnbY8LCyclin-dependent kinase 22.7.11.220.495
1oitHDTCyclin-dependent kinase 22.7.11.220.494
3qxpX64Cyclin-dependent kinase 22.7.11.220.494
2w06FRVCyclin-dependent kinase 22.7.11.220.490
3qxoX65Cyclin-dependent kinase 22.7.11.220.490
1ke6LS2Cyclin-dependent kinase 22.7.11.220.489
2w17I19Cyclin-dependent kinase 22.7.11.220.489
3rpo24ZCyclin-dependent kinase 22.7.11.220.489
1hckATPCyclin-dependent kinase 22.7.11.220.488
1p2a5BNCyclin-dependent kinase 22.7.11.220.488
2vthLZ2Cyclin-dependent kinase 22.7.11.220.488
2r3lSCWCyclin-dependent kinase 22.7.11.220.487
3fz1B98Cyclin-dependent kinase 22.7.11.220.486
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.485
3ti1B49Cyclin-dependent kinase 22.7.11.220.485
3unj0BXCyclin-dependent kinase 22.7.11.220.485
2c6iDT1Cyclin-dependent kinase 22.7.11.220.484
1ke7LS3Cyclin-dependent kinase 22.7.11.220.483
4lyn1YGCyclin-dependent kinase 22.7.11.220.482
1w8cN69Cyclin-dependent kinase 22.7.11.220.481
1pxpCK8Cyclin-dependent kinase 22.7.11.220.480
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.478
2vv9IM9Cyclin-dependent kinase 22.7.11.220.478
3qqhX0ACyclin-dependent kinase 22.7.11.220.477
3r7yZ04Cyclin-dependent kinase 22.7.11.220.477
3ral04ZCyclin-dependent kinase 22.7.11.220.475
3rk507ZCyclin-dependent kinase 22.7.11.220.475
2r3kSCQCyclin-dependent kinase 22.7.11.220.474
2vtrLZBCyclin-dependent kinase 22.7.11.220.474
3rpy27ZCyclin-dependent kinase 22.7.11.220.473
4fkj11KCyclin-dependent kinase 22.7.11.220.473
3qqlX03Cyclin-dependent kinase 22.7.11.220.472
1b38ATPCyclin-dependent kinase 22.7.11.220.471
1urwI1PCyclin-dependent kinase 22.7.11.220.471
3qtqX35Cyclin-dependent kinase 22.7.11.220.471
3r71X86Cyclin-dependent kinase 22.7.11.220.471
3qzhX69Cyclin-dependent kinase 22.7.11.220.470
3r83Z14Cyclin-dependent kinase 22.7.11.220.470
1h1s4SPCyclin-dependent kinase 22.7.11.220.469
3rm618ZCyclin-dependent kinase 22.7.11.220.466
3rm719ZCyclin-dependent kinase 22.7.11.220.465
1di8DTQCyclin-dependent kinase 22.7.11.220.463
4ez30S0Cyclin-dependent kinase 22.7.11.220.462
2vttLZDCyclin-dependent kinase 22.7.11.220.461
3sqq99ZCyclin-dependent kinase 22.7.11.220.461
1aq1STUCyclin-dependent kinase 22.7.11.220.460
3r7vZ02Cyclin-dependent kinase 22.7.11.220.460
1e1xNW1Cyclin-dependent kinase 22.7.11.220.459
1ke9LS5Cyclin-dependent kinase 22.7.11.220.458
3r73X87Cyclin-dependent kinase 22.7.11.220.458
3r7uX96Cyclin-dependent kinase 22.7.11.220.458
3wblPDYCyclin-dependent kinase 22.7.11.220.458
1gii1PUCyclin-dependent kinase 22.7.11.220.457
1ke8LS4Cyclin-dependent kinase 22.7.11.220.457
2exmZIPCyclin-dependent kinase 22.7.11.220.457
3r9hZ67Cyclin-dependent kinase 22.7.11.220.457
2duv371Cyclin-dependent kinase 22.7.11.220.456
2vu3LZECyclin-dependent kinase 22.7.11.220.456
2b53D23Cyclin-dependent kinase 22.7.11.220.455
3pxyJWSCyclin-dependent kinase 22.7.11.220.455
3r6xX84Cyclin-dependent kinase 22.7.11.220.455
1fvv107Cyclin-dependent kinase 22.7.11.220.454
3r9oZ71Cyclin-dependent kinase 22.7.11.220.454
4fkr45KCyclin-dependent kinase 22.7.11.220.454
2c6lDT4Cyclin-dependent kinase 22.7.11.220.453
1h1r6CPCyclin-dependent kinase 22.7.11.220.451
2c5yMTWCyclin-dependent kinase 22.7.11.220.451
2uznC96Cyclin-dependent kinase 22.7.11.220.449
3qqkX02Cyclin-dependent kinase 22.7.11.220.449
1pxkCK3Cyclin-dependent kinase 22.7.11.220.447
1v1k3FPCyclin-dependent kinase 22.7.11.220.447
4fx360KCyclin-dependent kinase 22.7.11.220.447
2vtsLZCCyclin-dependent kinase 22.7.11.220.446
1dm2HMDCyclin-dependent kinase 22.7.11.220.445
1oguST8Cyclin-dependent kinase 22.7.11.220.445
4fkw62KCyclin-dependent kinase 22.7.11.220.445
2r64740Cyclin-dependent kinase 22.7.11.220.443
4fklCK2Cyclin-dependent kinase 22.7.11.220.443
2r3p3SCCyclin-dependent kinase 22.7.11.220.442
2r3iSCFCyclin-dependent kinase 22.7.11.220.441
2fvdLIACyclin-dependent kinase 22.7.11.220.440