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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2xefAR8Glutamate carboxypeptidase 23.4.17.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2xefAR8Glutamate carboxypeptidase 23.4.17.211.000
2xejOKDGlutamate carboxypeptidase 23.4.17.210.716
2xeiARKGlutamate carboxypeptidase 23.4.17.210.683
2xegCI9Glutamate carboxypeptidase 23.4.17.210.634