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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2x9vTMQPteridine reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2x9vTMQPteridine reductase/1.000
2wd7VGDPteridine reductase/0.615
2x9nAX3Pteridine reductase/0.595
3jqgAX6Pteridine reductase, putative/0.593
3jqbDX6Pteridine reductase, putative/0.580
3jq9AX1Pteridine reductase, putative/0.579
2vz0D64Pteridine reductase/0.576
3jq7DX2Pteridine reductase, putative/0.575
3jq8DX3Pteridine reductase, putative/0.565
2yhuWHFPteridine reductase/0.539
3jq6DX1Pteridine reductase, putative/0.536
3bmcFOLPteridine reductase/0.530
3bmnAX3Pteridine reductase/0.528
3mcvMCVPteridine reductase/0.525
3gn2AX8Pteridine reductase/0.522
3bmqAX5Pteridine reductase/0.513
2x9gLYAPteridine reductase/0.500
1p33MTXPteridine reductase 11.5.1.330.489
2bfmTOPPteridine reductase 11.5.1.330.478
3jqcJU2Pteridine reductase, putative/0.477
3bmoNAPPteridine reductase/0.468
2wd8VGFPteridine reductase/0.467
2bf7HBIPteridine reductase 11.5.1.330.459
1mxfMTXPutative pteridine reductase 2/0.457
3h4vDVPPteridine reductase 11.5.1.330.455
1e92HBIPteridine reductase 11.5.1.330.450
2bfpH4BPteridine reductase 11.5.1.330.448