sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2x9n	AX3	Pteridine reductase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2x9n	AX3	Pteridine reductase	/	1.000
2wd7	VGD	Pteridine reductase	/	0.624
3jq9	AX1	Pteridine reductase, putative	/	0.582
3jqg	AX6	Pteridine reductase, putative	/	0.560
3jqb	DX6	Pteridine reductase, putative	/	0.556
2yhu	WHF	Pteridine reductase	/	0.554
3bmc	FOL	Pteridine reductase	/	0.549
3mcv	MCV	Pteridine reductase	/	0.543
3jq7	DX2	Pteridine reductase, putative	/	0.531
2x9g	LYA	Pteridine reductase	/	0.520
3bmn	AX3	Pteridine reductase	/	0.503
2x9v	TMQ	Pteridine reductase	/	0.482
3bmo	NAP	Pteridine reductase	/	0.452