sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 1.000 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 1.000 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.610 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.610 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.580 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.580 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.545 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.545 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.526 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.518 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.508 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.506 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.506 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.505 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.502 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.500 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.496 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.495 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.495 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.492 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.491 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.487 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.487 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.486 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.485 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.484 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.484 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.483 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.483 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.482 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.482 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.482 | |
| 4jsj | QJ7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.482 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.481 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.481 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.480 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.480 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.479 | |
| 4uga | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.479 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.478 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.478 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.478 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.478 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.477 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.477 | |
| 4o7u | THF | Thymidylate synthase | / | 0.477 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.476 | |
| 1zs6 | ADP | Nucleoside diphosphate kinase 3 | 2.7.4.6 | 0.476 | |
| 3eem | 53V | Uncharacterized protein | / | 0.476 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.476 | |
| 4l8g | GDP | GTPase KRas | / | 0.476 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.476 | |
| 3up3 | XCA | aceDAF-12 | / | 0.475 | |
| 4jse | QJ2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.475 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.475 | |
| 5djt | FMN | NPH1-2 | / | 0.475 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 4kwh | NAP | Reductase homolog | / | 0.474 | |
| 4ldj | GDP | GTPase KRas | / | 0.474 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.473 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.473 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 2bxq | IMN | Serum albumin | / | 0.472 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.472 | |
| 2kce | D16 | Thymidylate synthase | / | 0.472 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.472 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.472 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.472 | |
| 4lv6 | GDP | GTPase KRas | / | 0.472 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.472 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.472 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.471 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.471 | |
| 4g0n | GNP | GTPase HRas | / | 0.471 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.471 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.471 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.470 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.470 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.470 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.470 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.469 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.469 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.469 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.469 | |
| 4tq9 | GDP | GTPase KRas | / | 0.469 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.468 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.468 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.468 | |
| 3nln | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
| 5ebu | FMN | Lactate oxidase | / | 0.468 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.467 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.467 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.467 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.467 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.467 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.467 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.466 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.466 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.466 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.466 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.465 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.465 | |
| 2ycn | P61 | Tyrosine phenol-lyase | 4.1.99.2 | 0.465 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 5a3b | APR | SIR2 family protein | / | 0.465 | |
| 5efw | FMN | NPH1-1 | / | 0.465 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.464 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.464 | |
| 1rxh | BNI | Streptavidin | / | 0.464 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3eej | 53R | Uncharacterized protein | / | 0.464 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.464 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.464 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.463 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1g28 | FMN | PHY3 | / | 0.463 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.463 | |
| 2bxm | IMN | Serum albumin | / | 0.463 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2dxe | GDP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.463 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.463 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.463 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.463 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.463 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.463 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.463 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.463 | |
| 5dju | FMN | NPH1-2 | / | 0.463 | |
| 1osv | CHC | Bile acid receptor | / | 0.462 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.462 | |
| 2j5s | KTA | Alr4455 protein | / | 0.462 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.462 | |
| 3fmo | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.462 | |
| 3k9l | GNP | GTPase HRas | / | 0.462 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.461 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.461 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.461 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.461 | |
| 3ruv | ANP | Chaperonin | / | 0.461 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.461 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.461 | |
| 4fvx | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.461 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.461 | |
| 1kzi | THG | Thymidylate synthase | / | 0.460 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.460 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.460 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.460 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3jx5 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.460 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.460 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.459 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.459 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.459 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.459 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.459 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.459 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.459 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.459 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.459 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.458 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1sez | OMN | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.458 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.458 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.458 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.458 | |
| 2v1a | FMN | NPH1-1 | / | 0.458 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.458 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4dsn | GCP | GTPase KRas | / | 0.458 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.458 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.457 | |
| 1q3s | ADP | Thermosome subunit alpha | / | 0.457 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2bun | FAD | AppA protein | / | 0.457 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3c13 | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.457 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.456 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.456 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.456 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.456 | |
| 1vza | UMP | Thymidylate synthase | / | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.456 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.456 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.456 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 4yak | ACO | Acyl-CoA synthetase (NDP forming) | / | 0.456 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.455 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.455 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.455 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.455 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 2v0u | FMN | NPH1-1 | / | 0.455 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.455 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.455 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.455 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.455 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.455 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.455 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.455 | |
| 4epw | GDP | GTPase KRas | / | 0.455 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.455 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.455 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.454 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2fto | TMP | Thymidylate synthase | / | 0.454 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.454 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.454 | |
| 3dg8 | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3eld | SFG | Methyltransferase | / | 0.454 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.454 | |
| 3oiu | GNP | GTPase HRas | / | 0.454 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4ql3 | GDP | GTPase KRas | / | 0.454 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.454 | |
| 4zas | TYD | CalS13 | / | 0.454 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.454 | |
| 5k0s | 0OU | Methionine--tRNA ligase | / | 0.454 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.453 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.453 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3ely | SAH | Methyltransferase | / | 0.453 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.453 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.453 | |
| 4epx | GDP | GTPase KRas | / | 0.453 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4z28 | BTN | Hoefavidin | / | 0.453 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.453 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.452 | |
| 2f02 | ATP | Tagatose-6-phosphate kinase | / | 0.452 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.452 | |
| 3v49 | PK0 | Androgen receptor | / | 0.452 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.452 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.452 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4q02 | GDP | GTPase KRas | / | 0.452 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
| 1tsv | UMP | Thymidylate synthase | / | 0.451 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.451 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2jfz | 003 | Glutamate racemase | / | 0.451 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 2rgg | GNP | GTPase HRas | / | 0.451 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.451 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.451 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 4bls | APC | NTPase P4 | / | 0.451 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4ymg | SAM | Putative SAM-dependent O-methyltranferase | / | 0.451 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.451 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.451 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.450 | |
| 1unh | IXM | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.450 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.450 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.450 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.450 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.450 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4cvb | PQQ | Alcohol dehydrogenase | / | 0.450 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.450 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.450 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.450 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.450 | |
| 5dx8 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.450 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.450 | |
| 1avd | BTN | Avidin | / | 0.449 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.449 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.449 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.449 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 3pxv | FMN | Nitroreductase | / | 0.449 | |
| 3svj | 4LI | Peptide deformylase | / | 0.449 | |
| 3up0 | D7S | aceDAF-12 | / | 0.449 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.449 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ozn | ATP | Ammonium transporter | / | 0.449 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.449 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.448 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.448 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.448 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3pyz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.448 | |
| 3qj7 | UMP | Thymidylate synthase ThyA | / | 0.448 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3vws | VWS | Genome polyprotein | / | 0.448 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.448 | |
| 4cje | Q31 | Integrase | / | 0.448 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.448 | |
| 4iaf | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.448 | |
| 4lwb | QJ8 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.448 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.447 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.447 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 3dqr | JI2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 3tym | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.447 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.447 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.447 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.446 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.446 | |
| 1q24 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1swt | BTN | Streptavidin | / | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.446 | |
| 3frk | TQP | QdtB | / | 0.446 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.446 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.446 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.446 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4q03 | GDP | GTPase KRas | / | 0.446 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 4xvr | GNP | GTPase HRas | / | 0.446 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5cae | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.446 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.445 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.445 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.445 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.445 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.445 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.445 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.445 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.445 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.445 | |
| 2vqd | AP2 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.445 | |
| 3c3y | SAH | O-methyltransferase | / | 0.445 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.445 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.445 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.445 | |
| 4b8z | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.445 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.445 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4e9a | QAP | Peptide deformylase | / | 0.445 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.445 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4hpt | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.445 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.445 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.445 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.444 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.444 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.444 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 2rtm | IMI | Streptavidin | / | 0.444 | |
| 2uyw | BTN | Avd protein | / | 0.444 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.444 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 3fhi | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.444 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.444 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.444 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.444 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4k5e | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.444 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.443 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.443 | |
| 2rti | GLL | Streptavidin | / | 0.443 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.443 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.443 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.443 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.443 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.443 | |
| 3wti | CT4 | Acetylcholine-binding protein | / | 0.443 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.443 | |
| 4e2b | FMN | Dehydrogenase | / | 0.443 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.443 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.443 | |
| 5epe | SAH | Uncharacterized protein | / | 0.443 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.443 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.442 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.442 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.442 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.442 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.442 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.442 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.442 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.442 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.442 | |
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.442 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.442 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.442 | |
| 4h6p | FMN | Chromate reductase | / | 0.442 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1cgk | NAR | Chalcone synthase 2 | 2.3.1.74 | 0.441 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 1nhw | TCC | Enoyl-ACP reductase | / | 0.441 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.441 | |
| 1srf | MTB | Streptavidin | / | 0.441 | |
| 1w2g | THM | Thymidylate kinase | 2.7.4.9 | 0.441 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.441 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.441 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.441 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.441 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2rte | BTN | Streptavidin | / | 0.441 | |
| 2uyy | NA7 | Putative oxidoreductase GLYR1 | 1 | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3jwu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3jx4 | J11 | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 3rqm | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4dem | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.441 | |
| 4gqe | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4h0u | UMP | Thymidylate synthase | / | 0.441 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.441 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.441 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 1luq | BTN | Streptavidin | / | 0.440 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.440 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.440 | |
| 1zxl | JP1 | Enoyl-ACP reductase | / | 0.440 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.440 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2c96 | ATP | Psp operon transcriptional activator | / | 0.440 | |
| 2czf | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.440 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2j5b | TYE | Tyrosine--tRNA ligase | 6.1.1.1 | 0.440 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3ewr | APR | Replicase polyprotein 1a | 3.4.22 | 0.440 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.440 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3jx4 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.440 | |
| 3qly | 55V | Uncharacterized protein | / | 0.440 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3tc5 | 3T5 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 5.2.1.8 | 0.440 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.440 | |
| 3zqt | TES | Androgen receptor | / | 0.440 | |
| 4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.440 | |
| 4isk | UMP | Thymidylate synthase | / | 0.440 | |
| 4jsf | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.440 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.440 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.440 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.440 |