sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.863 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.858 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.856 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.852 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.847 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.812 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.804 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.792 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.775 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.773 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.769 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.594 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.579 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.576 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.571 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.567 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.557 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.552 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.547 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.532 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.531 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.529 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.525 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.524 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.524 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.520 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.513 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 4iae | 1DX | Alr2278 protein | / | 0.501 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.493 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.493 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.493 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.491 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.490 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.488 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.488 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.486 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.486 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.486 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.482 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.481 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.481 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.481 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.477 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.477 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.476 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.476 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.476 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.475 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.474 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.474 | |
| 4iah | 1DX | Alr2278 protein | / | 0.474 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.474 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.473 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.472 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.471 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.471 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.471 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.470 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.469 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.469 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.469 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.467 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 4rel | KMP | Glycosyltransferase | / | 0.467 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.467 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.467 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.466 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.466 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.466 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.466 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.465 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.464 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.464 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.464 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.463 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.463 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.463 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.463 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 3a6r | FMN | FMN-binding protein | / | 0.462 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.462 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.462 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.462 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.461 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.461 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.461 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.461 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.460 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.460 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.460 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.460 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.460 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.460 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.459 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.459 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.459 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.459 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.458 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.458 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.458 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.458 | |
| 3b9l | AZZ | Serum albumin | / | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.458 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.458 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.458 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.457 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.457 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.457 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.457 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.456 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.456 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.455 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.455 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.454 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.454 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.454 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.454 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.453 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.453 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.453 | |
| 1c7o | PPG | Hemolysin | / | 0.452 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.452 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.452 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.451 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.451 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.451 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.451 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.451 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.451 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.450 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.450 | |
| 4y1b | NAP | AntE | / | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.449 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.449 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.449 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.449 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.449 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.449 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.448 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1swt | BTN | Streptavidin | / | 0.448 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.448 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.448 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.448 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2zt5 | B4P | Glycine--tRNA ligase | / | 0.448 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.448 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.448 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.448 | |
| 4e32 | DWN | Methyltransferase | / | 0.448 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.448 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.447 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.447 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.447 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.447 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.447 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.447 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.447 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.447 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4n1g | CEI | Obelin | / | 0.447 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.447 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.446 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.446 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.446 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4e2w | JHZ | Methyltransferase | / | 0.446 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.446 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.446 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.445 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.445 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.445 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.445 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.445 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.445 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.445 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.444 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.444 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.444 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.444 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.444 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.444 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.444 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.444 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.444 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.444 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.444 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.444 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.444 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.443 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.443 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.443 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.443 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.443 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.443 | |
| 3zlq | 6T9 | Beta-secretase 2 | 3.4.23.45 | 0.443 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.443 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.443 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.442 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.442 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3eld | SFG | Methyltransferase | / | 0.442 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.442 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.442 | |
| 4u7w | NDP | MxaA | / | 0.442 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.441 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.441 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 2j08 | IRF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.441 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.441 | |
| 3pft | FMN | Flavin reductase | / | 0.441 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.441 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.441 | |
| 4jic | FMN | GTN Reductase | / | 0.441 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.440 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.440 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.440 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.440 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.440 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.440 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.440 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.440 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.440 | |
| 3vy5 | FMN | FMN-binding protein | / | 0.440 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.440 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.440 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.440 |