sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2wd7	VGD	Pteridine reductase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2wd7	VGD	Pteridine reductase	/	1.000
2x9n	AX3	Pteridine reductase	/	0.613
3jqb	DX6	Pteridine reductase, putative	/	0.566
2yhu	WHF	Pteridine reductase	/	0.565
3bmc	FOL	Pteridine reductase	/	0.562
3jq9	AX1	Pteridine reductase, putative	/	0.559
3mcv	MCV	Pteridine reductase	/	0.551
3jqg	AX6	Pteridine reductase, putative	/	0.546
2x9g	LYA	Pteridine reductase	/	0.523
3jq7	DX2	Pteridine reductase, putative	/	0.510
3bmn	AX3	Pteridine reductase	/	0.489
2x9v	TMQ	Pteridine reductase	/	0.459
3bmo	NAP	Pteridine reductase	/	0.450