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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2w1hL0FCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2w1hL0FCyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.529
3r9dX6BCyclin-dependent kinase 22.7.11.220.528
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.522
2c6o4SPCyclin-dependent kinase 22.7.11.220.518
2uznC96Cyclin-dependent kinase 22.7.11.220.517
2vtrLZBCyclin-dependent kinase 22.7.11.220.515
1gih1PUCyclin-dependent kinase 22.7.11.220.514
1p2a5BNCyclin-dependent kinase 22.7.11.220.505
3lfnA27Cyclin-dependent kinase 22.7.11.220.502
3lfsA07Cyclin-dependent kinase 22.7.11.220.495
1oitHDTCyclin-dependent kinase 22.7.11.220.494
3rkb12ZCyclin-dependent kinase 22.7.11.220.494
1di8DTQCyclin-dependent kinase 22.7.11.220.492
4bgh3I6Cyclin-dependent kinase 22.7.11.220.492
2bheBRYCyclin-dependent kinase 22.7.11.220.490
3qxpX64Cyclin-dependent kinase 22.7.11.220.488
2r3lSCWCyclin-dependent kinase 22.7.11.220.487
1v1k3FPCyclin-dependent kinase 22.7.11.220.486
3qtrX36Cyclin-dependent kinase 22.7.11.220.485
3rk708ZCyclin-dependent kinase 22.7.11.220.485
1pxmCK5Cyclin-dependent kinase 22.7.11.220.484
1g5sI17Cyclin-dependent kinase 22.7.11.220.483
4acm7YGCyclin-dependent kinase 22.7.11.220.483
1ke5LS1Cyclin-dependent kinase 22.7.11.220.482
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.482
3rjc06ZCyclin-dependent kinase 22.7.11.220.481
2vthLZ2Cyclin-dependent kinase 22.7.11.220.480
3r7iX9ICyclin-dependent kinase 22.7.11.220.480
4fkpLS5Cyclin-dependent kinase 22.7.11.220.480
1y91CT9Cyclin-dependent kinase 22.7.11.220.479
3qwjX6ACyclin-dependent kinase 22.7.11.220.477
3rmf20ZCyclin-dependent kinase 22.7.11.220.477
3s1h56ZCyclin-dependent kinase 22.7.11.220.477
3rak03ZCyclin-dependent kinase 22.7.11.220.476
3qzgX67Cyclin-dependent kinase 22.7.11.220.475
3sw418KCyclin-dependent kinase 22.7.11.220.474
4fkv61KCyclin-dependent kinase 22.7.11.220.474
2r64740Cyclin-dependent kinase 22.7.11.220.472
2vv9IM9Cyclin-dependent kinase 22.7.11.220.471
2b52D42Cyclin-dependent kinase 22.7.11.220.470
4fki09KCyclin-dependent kinase 22.7.11.220.470
1ke6LS2Cyclin-dependent kinase 22.7.11.220.469
2r3kSCQCyclin-dependent kinase 22.7.11.220.469
3rk909ZCyclin-dependent kinase 22.7.11.220.467
2btsU32Cyclin-dependent kinase 22.7.11.220.464
3rni21ZCyclin-dependent kinase 22.7.11.220.464
2w06FRVCyclin-dependent kinase 22.7.11.220.463
3r8lZ30Cyclin-dependent kinase 22.7.11.220.463
2j9mPY8Cyclin-dependent kinase 22.7.11.220.462
3rpv26ZCyclin-dependent kinase 22.7.11.220.462
1oirHDYCyclin-dependent kinase 22.7.11.220.461
4fkq42KCyclin-dependent kinase 22.7.11.220.461
1gii1PUCyclin-dependent kinase 22.7.11.220.460
1w0xOLOCyclin-dependent kinase 22.7.11.220.460
3sw719KCyclin-dependent kinase 22.7.11.220.459
1h1s4SPCyclin-dependent kinase 22.7.11.220.458
2xmyCDKCyclin-dependent kinase 22.7.11.220.458
3s2pPMUCyclin-dependent kinase 22.7.11.220.457
4erwSTUCyclin-dependent kinase 22.7.11.220.457
1pxlCK4Cyclin-dependent kinase 22.7.11.220.456
3unk0BYCyclin-dependent kinase 22.7.11.220.456
4fkg4CKCyclin-dependent kinase 22.7.11.220.456
2fvdLIACyclin-dependent kinase 22.7.11.220.455
2vttLZDCyclin-dependent kinase 22.7.11.220.455
3qu0X40Cyclin-dependent kinase 22.7.11.220.455
2vu3LZECyclin-dependent kinase 22.7.11.220.454
3sqq99ZCyclin-dependent kinase 22.7.11.220.454
2uzoC62Cyclin-dependent kinase 22.7.11.220.453
4ek610KCyclin-dependent kinase 22.7.11.220.453
4fkr45KCyclin-dependent kinase 22.7.11.220.453
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.452
2vtsLZCCyclin-dependent kinase 22.7.11.220.451
3r83Z14Cyclin-dependent kinase 22.7.11.220.451
4fkj11KCyclin-dependent kinase 22.7.11.220.451
1ke7LS3Cyclin-dependent kinase 22.7.11.220.450
3qtxX43Cyclin-dependent kinase 22.7.11.220.450
3qtuX44Cyclin-dependent kinase 22.7.11.220.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
3iggEFQCyclin-dependent kinase 22.7.11.220.448
3rpo24ZCyclin-dependent kinase 22.7.11.220.448
2w05FRTCyclin-dependent kinase 22.7.11.220.445
4fko20KCyclin-dependent kinase 22.7.11.220.444
2a0cCK9Cyclin-dependent kinase 22.7.11.220.443
3uli1N3Cyclin-dependent kinase 22.7.11.220.443
2btrU73Cyclin-dependent kinase 22.7.11.220.442
2r3jSCJCyclin-dependent kinase 22.7.11.220.442
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.442
4eon1ROCyclin-dependent kinase 22.7.11.220.440