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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vtsLZCCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vtsLZCCyclin-dependent kinase 22.7.11.221.000
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.530
1w8cN69Cyclin-dependent kinase 22.7.11.220.523
4fklCK2Cyclin-dependent kinase 22.7.11.220.518
1oitHDTCyclin-dependent kinase 22.7.11.220.516
2a0cCK9Cyclin-dependent kinase 22.7.11.220.490
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.487
3r83Z14Cyclin-dependent kinase 22.7.11.220.483
2c6lDT4Cyclin-dependent kinase 22.7.11.220.482
3rpo24ZCyclin-dependent kinase 22.7.11.220.469
3r71X86Cyclin-dependent kinase 22.7.11.220.464
3rahO1ZCyclin-dependent kinase 22.7.11.220.463
1y91CT9Cyclin-dependent kinase 22.7.11.220.462
4ek816KCyclin-dependent kinase 22.7.11.220.462
2exmZIPCyclin-dependent kinase 22.7.11.220.460
3s2pPMUCyclin-dependent kinase 22.7.11.220.458
4fkg4CKCyclin-dependent kinase 22.7.11.220.458
1aq1STUCyclin-dependent kinase 22.7.11.220.457
4ek610KCyclin-dependent kinase 22.7.11.220.455
3r8vZ62Cyclin-dependent kinase 22.7.11.220.454
2btrU73Cyclin-dependent kinase 22.7.11.220.453
3rk708ZCyclin-dependent kinase 22.7.11.220.452
1v1k3FPCyclin-dependent kinase 22.7.11.220.450
2b52D42Cyclin-dependent kinase 22.7.11.220.449
1ke5LS1Cyclin-dependent kinase 22.7.11.220.446
2c6kDT2Cyclin-dependent kinase 22.7.11.220.446
3lfnA27Cyclin-dependent kinase 22.7.11.220.446
3rk909ZCyclin-dependent kinase 22.7.11.220.442
2a4lRRCCyclin-dependent kinase 22.7.11.220.441
3r1yX76Cyclin-dependent kinase 22.7.11.220.441
2uznC96Cyclin-dependent kinase 22.7.11.220.440