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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vtpLZ9Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vtpLZ9Cyclin-dependent kinase 22.7.11.221.000
1pxmCK5Cyclin-dependent kinase 22.7.11.220.586
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.586
2c6o4SPCyclin-dependent kinase 22.7.11.220.575
3lfnA27Cyclin-dependent kinase 22.7.11.220.574
2uzoC62Cyclin-dependent kinase 22.7.11.220.569
3r83Z14Cyclin-dependent kinase 22.7.11.220.558
4fkq42KCyclin-dependent kinase 22.7.11.220.553
1ke5LS1Cyclin-dependent kinase 22.7.11.220.549
4ek610KCyclin-dependent kinase 22.7.11.220.546
2r3mSCXCyclin-dependent kinase 22.7.11.220.533
4fki09KCyclin-dependent kinase 22.7.11.220.530
2r3jSCJCyclin-dependent kinase 22.7.11.220.529
2a0cCK9Cyclin-dependent kinase 22.7.11.220.526
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.524
2btrU73Cyclin-dependent kinase 22.7.11.220.521
4fkpLS5Cyclin-dependent kinase 22.7.11.220.521
3s2pPMUCyclin-dependent kinase 22.7.11.220.517
2btsU32Cyclin-dependent kinase 22.7.11.220.516
2vthLZ2Cyclin-dependent kinase 22.7.11.220.516
3rahO1ZCyclin-dependent kinase 22.7.11.220.515
2c6lDT4Cyclin-dependent kinase 22.7.11.220.514
3qzgX67Cyclin-dependent kinase 22.7.11.220.511
3s1h56ZCyclin-dependent kinase 22.7.11.220.511
4fkt48KCyclin-dependent kinase 22.7.11.220.511
1oitHDTCyclin-dependent kinase 22.7.11.220.507
3r7yZ04Cyclin-dependent kinase 22.7.11.220.507
3lfqA28Cyclin-dependent kinase 22.7.11.220.505
3r8lZ30Cyclin-dependent kinase 22.7.11.220.503
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.501
2a4lRRCCyclin-dependent kinase 22.7.11.220.500
2r3p3SCCyclin-dependent kinase 22.7.11.220.500
3r1yX76Cyclin-dependent kinase 22.7.11.220.499
1v1k3FPCyclin-dependent kinase 22.7.11.220.498
2vtsLZCCyclin-dependent kinase 22.7.11.220.497
3rm719ZCyclin-dependent kinase 22.7.11.220.497
3sqq99ZCyclin-dependent kinase 22.7.11.220.497
3r8vZ62Cyclin-dependent kinase 22.7.11.220.496
4fklCK2Cyclin-dependent kinase 22.7.11.220.495
3ezvEZVCyclin-dependent kinase 22.7.11.220.493
4fkj11KCyclin-dependent kinase 22.7.11.220.493
1ykr628Cyclin-dependent kinase 22.7.11.220.490
2r3iSCFCyclin-dependent kinase 22.7.11.220.490
1gii1PUCyclin-dependent kinase 22.7.11.220.487
1w8cN69Cyclin-dependent kinase 22.7.11.220.487
2r3lSCWCyclin-dependent kinase 22.7.11.220.487
3r9nZ68Cyclin-dependent kinase 22.7.11.220.487
3qxoX65Cyclin-dependent kinase 22.7.11.220.485
4bgh3I6Cyclin-dependent kinase 22.7.11.220.484
1pxoCK7Cyclin-dependent kinase 22.7.11.220.483
3lfsA07Cyclin-dependent kinase 22.7.11.220.483
1oirHDYCyclin-dependent kinase 22.7.11.220.482
3r7vZ02Cyclin-dependent kinase 22.7.11.220.482
1w0xOLOCyclin-dependent kinase 22.7.11.220.481
3qwjX6ACyclin-dependent kinase 22.7.11.220.481
3rni21ZCyclin-dependent kinase 22.7.11.220.479
1ke7LS3Cyclin-dependent kinase 22.7.11.220.477
1ke9LS5Cyclin-dependent kinase 22.7.11.220.477
2c6kDT2Cyclin-dependent kinase 22.7.11.220.476
3sw719KCyclin-dependent kinase 22.7.11.220.476
1h0w207Cyclin-dependent kinase 22.7.11.220.472
2exmZIPCyclin-dependent kinase 22.7.11.220.472
2w06FRVCyclin-dependent kinase 22.7.11.220.472
2uznC96Cyclin-dependent kinase 22.7.11.220.470
4fkg4CKCyclin-dependent kinase 22.7.11.220.470
1gih1PUCyclin-dependent kinase 22.7.11.220.469
2w1hL0FCyclin-dependent kinase 22.7.11.220.469
3qxpX64Cyclin-dependent kinase 22.7.11.220.469
3fz1B98Cyclin-dependent kinase 22.7.11.220.468
3r7uX96Cyclin-dependent kinase 22.7.11.220.468
3rjc06ZCyclin-dependent kinase 22.7.11.220.468
2r64740Cyclin-dependent kinase 22.7.11.220.467
3iggEFQCyclin-dependent kinase 22.7.11.220.465
4ek816KCyclin-dependent kinase 22.7.11.220.465
3qqlX03Cyclin-dependent kinase 22.7.11.220.464
2w05FRTCyclin-dependent kinase 22.7.11.220.462
3rk909ZCyclin-dependent kinase 22.7.11.220.462
2b53D23Cyclin-dependent kinase 22.7.11.220.460
3r73X87Cyclin-dependent kinase 22.7.11.220.460
3rpo24ZCyclin-dependent kinase 22.7.11.220.460
3r1sX73Cyclin-dependent kinase 22.7.11.220.457
3pj8404Cyclin-dependent kinase 22.7.11.220.455
3rak03ZCyclin-dependent kinase 22.7.11.220.453
1ckpPVBCyclin-dependent kinase 22.7.11.220.451
3qtzX42Cyclin-dependent kinase 22.7.11.220.450
3rk708ZCyclin-dependent kinase 22.7.11.220.450
3rm618ZCyclin-dependent kinase 22.7.11.220.450
1g5sI17Cyclin-dependent kinase 22.7.11.220.449
2r3r6SCCyclin-dependent kinase 22.7.11.220.448
2c6iDT1Cyclin-dependent kinase 22.7.11.220.447
2r3o2SCCyclin-dependent kinase 22.7.11.220.447
2xmyCDKCyclin-dependent kinase 22.7.11.220.447
3rpv26ZCyclin-dependent kinase 22.7.11.220.446
4ez30S0Cyclin-dependent kinase 22.7.11.220.445
3wblPDYCyclin-dependent kinase 22.7.11.220.444
2fvdLIACyclin-dependent kinase 22.7.11.220.443
2b52D42Cyclin-dependent kinase 22.7.11.220.442
1b38ATPCyclin-dependent kinase 22.7.11.220.441
1e1xNW1Cyclin-dependent kinase 22.7.11.220.441
3qqkX02Cyclin-dependent kinase 22.7.11.220.441
3r9dX6BCyclin-dependent kinase 22.7.11.220.441
3sw418KCyclin-dependent kinase 22.7.11.220.441
3unk0BYCyclin-dependent kinase 22.7.11.220.441
4acm7YGCyclin-dependent kinase 22.7.11.220.441
1pxlCK4Cyclin-dependent kinase 22.7.11.220.440
3qqfX07Cyclin-dependent kinase 22.7.11.220.440