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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.685
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.660
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.653
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.623
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.617
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.607
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.589
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.583
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.579
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.574
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.512
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.512
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.472
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3dneLL1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3mv5XFERAC-alpha serine/threonine-protein kinase2.7.11.10.441