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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vgoAD5Aurora kinase B-A2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vgoAD5Aurora kinase B-A2.7.11.11.000
2bfyH1NAurora kinase B-A2.7.11.10.570
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.554
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.549
3efwAK8Aurora kinase A2.7.11.10.544
3ztxZTXAurora kinase B-A2.7.11.10.543
4gu94GUFocal adhesion kinase 12.7.10.20.543
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.541
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.535
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.534
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.534
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.533
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.533
4foc0UUALK tyrosine kinase receptor2.7.10.10.533
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.530
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.529
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.527
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.522
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.522
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.517
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.517
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.517
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.516
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.516
2vgpAD6Aurora kinase B-A2.7.11.10.515
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.513
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.513
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.512
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.512
4cd0AWJALK tyrosine kinase receptor2.7.10.10.512
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.512
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.511
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.511
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.510
4gu610NFocal adhesion kinase 12.7.10.20.510
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.509
4b99R4LMitogen-activated protein kinase 72.7.11.240.509
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.509
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.509
4i4e1BQFocal adhesion kinase 12.7.10.20.509
4fob0USALK tyrosine kinase receptor2.7.10.10.508
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.507
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.507
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.506
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.506
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.505
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.505
5aacVGHALK tyrosine kinase receptor2.7.10.10.505
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.504
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.504
3gubGUBDeath-associated protein kinase 12.7.11.10.504
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.503
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.502
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.502
5aaaVGHALK tyrosine kinase receptor2.7.10.10.502
4b8lA0PAurora kinase B-A2.7.11.10.501
2hog710Serine/threonine-protein kinase Chk12.7.11.10.500
2ijmATPFocal adhesion kinase 12.7.10.20.500
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.500
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.500
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.499
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.499
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.499
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.499
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.499
4fod0UVALK tyrosine kinase receptor2.7.10.10.498
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.498
5aabVGHALK tyrosine kinase receptor2.7.10.10.498
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.497
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.497
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.497
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.496
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.496
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.496
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.496
2j0lANPFocal adhesion kinase 12.7.10.20.495
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.495
4c02TAKActivin receptor type-12.7.11.300.495
4k8aK8AFocal adhesion kinase 12.7.10.20.495
2pwlACPFibroblast growth factor receptor 2/0.494
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.494
1i44ACPInsulin receptor2.7.10.10.493
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.493
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.493
2xp2VGHALK tyrosine kinase receptor2.7.10.10.493
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.493
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.492
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.492
4anqVGHALK tyrosine kinase receptor2.7.10.10.492
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.491
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.491
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.491
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
5av2KMPDeath-associated protein kinase 12.7.11.10.490
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.489
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.489
3a7hATPSerine/threonine-protein kinase 242.7.11.10.489
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.489
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.489
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.488
1pkdUCNCyclin-dependent kinase 22.7.11.220.487
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.487
4brxKGWFocal adhesion kinase 12.7.10.20.487
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.486
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.486
3a60STURibosomal protein S6 kinase beta-12.7.11.10.486
3a62STURibosomal protein S6 kinase beta-12.7.11.10.486
4loqSB4Mitogen-activated protein kinase 14/0.486
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.485
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.485
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.485
3igoANPCalmodulin-domain protein kinase 1, putative/0.485
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.485
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.485
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.485
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.485
4nj32KDCyclin-dependent kinase 22.7.11.220.485
3pxkPXKFocal adhesion kinase 12.7.10.20.484
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.484
4gmy0X5Tyrosine-protein kinase JAK2/0.484
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.484
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.483
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.483
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.483
3lctADPALK tyrosine kinase receptor2.7.10.10.483
3t8oATPRhodopsin kinase/0.483
4qmzB49Serine/threonine-protein kinase 242.7.11.10.483
1h1s4SPCyclin-dependent kinase 22.7.11.220.482
1zys199Serine/threonine-protein kinase Chk12.7.11.10.482
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.482
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.481
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.481
4b8mVX6Aurora kinase B-A2.7.11.10.481
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.481
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.481
4f650S9Fibroblast growth factor receptor 1/0.480
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.480
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.480
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.479
1u54ACPActivated CDC42 kinase 1/0.479
2uzlC94Cyclin-dependent kinase 22.7.11.220.479
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.479
3zh8C58Protein kinase C iota type2.7.11.130.479
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.479
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.479
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.479
4y95746Tyrosine-protein kinase/0.479
4yuqKS1Calmodulin-like domain protein kinase/0.479
2c5nCK8Cyclin-dependent kinase 22.7.11.220.478
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.478
4nka2K7Fibroblast growth factor receptor 1/0.478
2ijmADPFocal adhesion kinase 12.7.10.20.477
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.477
2x1nX1NCyclin-dependent kinase 22.7.11.220.477
3fz1B98Cyclin-dependent kinase 22.7.11.220.477
1ir3ANPInsulin receptor2.7.10.10.476
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.476
2etm7PYFocal adhesion kinase 12.7.10.20.476
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.476
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.476
4nk92K5Fibroblast growth factor receptor 1/0.476
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.475
3bqr4RBDeath-associated protein kinase 3/0.475
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.475
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.475
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.475
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.475
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.474
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.474
2qo9ANPEphrin type-A receptor 32.7.10.10.474
2wpa889Cyclin-dependent kinase 22.7.11.220.474
2xb7GUIALK tyrosine kinase receptor2.7.10.10.474
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.474
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.474
4gg70J8Hepatocyte growth factor receptor2.7.10.10.474
4gk2L66Ephrin type-A receptor 32.7.10.10.474
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.474
5e8xSTUTGF-beta receptor type-12.7.11.300.474
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.473
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.473
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.473
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.472
4ansVGHALK tyrosine kinase receptor2.7.10.10.472
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.472
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.472
4d58BI9Focal adhesion kinase 12.7.10.20.472
4gk3L87Ephrin type-A receptor 32.7.10.10.472
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.472
1aq1STUCyclin-dependent kinase 22.7.11.220.471
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.471
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.471
2cchATPCyclin-dependent kinase 22.7.11.220.471
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.471
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.471
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.471
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.471
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.470
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.470
2jkoBIJFocal adhesion kinase 12.7.10.20.470
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.470
2vrx447Aurora kinase B-A2.7.11.10.469
2vwu7X1Ephrin type-B receptor 42.7.10.10.469
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.469
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.469
2yfxVGHALK tyrosine kinase receptor2.7.10.10.469
4erwSTUCyclin-dependent kinase 22.7.11.220.469
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.469
4qnaX11Serine/threonine-protein kinase 242.7.11.10.469
4riyADPEpidermal growth factor receptor2.7.10.10.469
2v7a627Tyrosine-protein kinase ABL12.7.10.20.468
3a4pDFQHepatocyte growth factor receptor2.7.10.10.468
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.468
5auxKMPDeath-associated protein kinase 12.7.11.10.468
1xjdSTUProtein kinase C theta type2.7.11.130.467
2itnANPEpidermal growth factor receptor2.7.10.10.467
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.467
3qyw6PBMitogen-activated protein kinase 12.7.11.240.467
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.467
4hvh19RTyrosine-protein kinase JAK32.7.10.20.467
4wboANWRhodopsin kinase/0.467
1oecAA2Fibroblast growth factor receptor 2/0.466
1oiyN41Cyclin-dependent kinase 22.7.11.220.466
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.466
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.466
3ormAGSSerine/threonine protein kinase/0.466
3q5iANPProtein kinase, putative/0.466
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.466
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4eoi1ROCyclin-dependent kinase 22.7.11.220.466
4eol1ROCyclin-dependent kinase 22.7.11.220.466
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.466
4l9i8PRRhodopsin kinase/0.466
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.466
5auvAGIDeath-associated protein kinase 12.7.11.10.466
1bygSTUTyrosine-protein kinase CSK/0.465
2bkzSBCCyclin-dependent kinase 22.7.11.220.465
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.465
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.465
4eor4SPCyclin-dependent kinase 22.7.11.220.465
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.465
2uzbC75Cyclin-dependent kinase 22.7.11.220.464
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.464
3sheI85MAP kinase-activated protein kinase 32.7.11.10.464
3uyt0CKCasein kinase I isoform delta2.7.11.10.464
3oroAGSSerine/threonine protein kinase/0.463
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.463
3s4qNK0Mitogen-activated protein kinase 14/0.463
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.463
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.463
2i40BLZCyclin-dependent kinase 22.7.11.220.462
2w1fL0FAurora kinase A2.7.11.10.462
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.462
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.462
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.462
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.461
2xru400Aurora kinase A2.7.11.10.461
4ccbOFGALK tyrosine kinase receptor2.7.10.10.461
4erkOLOMitogen-activated protein kinase 12.7.11.240.461
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.460
2c6eHPMAurora kinase A2.7.11.10.460
2jkqVG8Focal adhesion kinase 12.7.10.20.460
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.460
3vquO22Dual specificity protein kinase TTK2.7.12.10.460
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.460
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.460
5auwQUEDeath-associated protein kinase 12.7.11.10.460
1e9hINRCyclin-dependent kinase 22.7.11.220.459
1oi9N20Cyclin-dependent kinase 22.7.11.220.459
1ol6ATPAurora kinase A2.7.11.10.459
1ykr628Cyclin-dependent kinase 22.7.11.220.459
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.459
2xa4AZ5Tyrosine-protein kinase JAK2/0.459
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3c4zADPRhodopsin kinase/0.459
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.459
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.459
4c3pACPAurora kinase A2.7.11.10.459
4f630S7Fibroblast growth factor receptor 1/0.459
4y93746Tyrosine-protein kinase/0.459
5dr6SKEAurora kinase A2.7.11.10.459
1unlRRCCyclin-dependent-like kinase 52.7.11.10.458
2acxANPG protein-coupled receptor kinase 62.7.11.160.458
2py3ACPFibroblast growth factor receptor 2/0.458
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.458
2w1eL0EAurora kinase A2.7.11.10.458
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.458
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.458
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.458
4h3qANPMitogen-activated protein kinase 12.7.11.240.458
4jia1K3Tyrosine-protein kinase JAK2/0.458
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.458
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.457
2fgiPD1Fibroblast growth factor receptor 1/0.457
3k5uPFQAurora kinase A2.7.11.10.457
4bb432WEphrin type-B receptor 42.7.10.10.457
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.457
4d4sBI9Focal adhesion kinase 12.7.10.20.457
4f640S8Fibroblast growth factor receptor 1/0.457
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.457
2j0m4STFocal adhesion kinase 12.7.10.20.456
2r64740Cyclin-dependent kinase 22.7.11.220.456
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.456
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.456
3c4xATPRhodopsin kinase/0.456
3lltANPProtein serine/threonine kinase-1/0.456
3vjoANPEpidermal growth factor receptor2.7.10.10.456
4fks46KCyclin-dependent kinase 22.7.11.220.456
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.456
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.456
4j97ACPFibroblast growth factor receptor 2/0.456
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.456
2vwx7X4Ephrin type-B receptor 42.7.10.10.455
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.455
3nynSGVG protein-coupled receptor kinase 62.7.11.160.455
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.455
3vs3VSETyrosine-protein kinase HCK2.7.10.20.455
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.455
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.455
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.455
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.455
4o0uADNAurora kinase A2.7.11.10.455
2wqeADPAurora kinase A2.7.11.10.454
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.454
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3tnwF18Cyclin-dependent kinase 22.7.11.220.454
4bcoT6QCyclin-dependent kinase 22.7.11.220.454
4c61LMMTyrosine-protein kinase JAK2/0.454
4eok4SPCyclin-dependent kinase 22.7.11.220.454
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.454
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.454
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1wvySTUDeath-associated protein kinase 12.7.11.10.453
2c6tDT5Cyclin-dependent kinase 22.7.11.220.453
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.453
2hk51BMTyrosine-protein kinase HCK2.7.10.20.453
2vwz7X6Ephrin type-B receptor 42.7.10.10.453
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4eomATPCyclin-dependent kinase 22.7.11.220.453
4ewhT77Activated CDC42 kinase 1/0.453
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.453
4fuxE75Mitogen-activated protein kinase 12.7.11.240.453
4i22IREEpidermal growth factor receptor2.7.10.10.453
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.453
4nifANPMitogen-activated protein kinase 12.7.11.240.453
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.453
5f0a1FBcGMP-dependent protein kinase, putative/0.453
1u4dDBQActivated CDC42 kinase 1/0.452
2ittAEEEpidermal growth factor receptor2.7.10.10.452
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.452
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.452
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3zmmF9JTyrosine-protein kinase JAK2/0.452
4fv9E71Mitogen-activated protein kinase 12.7.11.240.452
1oguST8Cyclin-dependent kinase 22.7.11.220.451
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.451
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.451
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2itpAEEEpidermal growth factor receptor2.7.10.10.451
2iw84SPCyclin-dependent kinase 22.7.11.220.451
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.451
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.451
2y6o1N1Ephrin type-A receptor 42.7.10.10.451
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.451
3bheBZNGag-Pol polyprotein3.4.23.160.451
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.451
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.451
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.451
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.451
4c62XWWTyrosine-protein kinase JAK2/0.451
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.451
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.451
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.451
1vyw292Cyclin-dependent kinase 22.7.11.220.450
2dwbANPAurora kinase A2.7.11.10.450
2j0k4STFocal adhesion kinase 12.7.10.20.450
2j4z626Aurora kinase A2.7.11.10.450
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.450
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.450
3qwkX62Cyclin-dependent kinase 22.7.11.220.450
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
2pulACPMethylthioribose kinase2.7.1.1000.449
2vwy7X5Ephrin type-B receptor 42.7.10.10.449
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.449
2wxvWXVCyclin-dependent kinase 22.7.11.220.449
2x6dX6DAurora kinase A2.7.11.10.449
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.449
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.449
3c4wATPRhodopsin kinase/0.449
3gu6ADPDeath-associated protein kinase 12.7.11.10.449
4ccuAWFALK tyrosine kinase receptor2.7.10.10.449
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.449
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.449
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.449
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.448
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.448
3ddqRRCCyclin-dependent kinase 22.7.11.220.448
3gxlQIGTGF-beta receptor type-12.7.11.300.448
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.448
3r9dX6BCyclin-dependent kinase 22.7.11.220.448
3s2pPMUCyclin-dependent kinase 22.7.11.220.448
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.448
5dr2ATPAurora kinase A2.7.11.10.448
1mp8ADPFocal adhesion kinase 12.7.10.20.447
2j50627Aurora kinase A2.7.11.10.447
2xikJ60Serine/threonine-protein kinase 252.7.11.10.447
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.447
3w18N13Aurora kinase A2.7.11.10.447
3w551FMMitogen-activated protein kinase 12.7.11.240.447
4i231C9Epidermal growth factor receptor2.7.10.10.447
4s34ANPMitogen-activated protein kinase 12.7.11.240.447
1rw8580TGF-beta receptor type-12.7.11.300.446
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.446
3bu5ATPInsulin receptor2.7.10.10.446
3ekx1UNGag-Pol polyprotein3.4.23.160.446
3r7iX9ICyclin-dependent kinase 22.7.11.220.446
3ttiKBIMitogen-activated protein kinase 102.7.11.240.446
3zep1NXTyrosine-protein kinase JAK32.7.10.20.446
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.446
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.446
4ih8B43Calmodulin-domain protein kinase 1/0.446
5av4GENDeath-associated protein kinase 12.7.11.10.446
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.445
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.445
1zrzBI1Protein kinase C iota type2.7.11.130.445
2b52D42Cyclin-dependent kinase 22.7.11.220.445
2c6o4SPCyclin-dependent kinase 22.7.11.220.445
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.445
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.445
2wotZZGTGF-beta receptor type-12.7.11.300.445
2yn8STUEphrin type-B receptor 42.7.10.10.445
3qqfX07Cyclin-dependent kinase 22.7.11.220.445
3ral04ZCyclin-dependent kinase 22.7.11.220.445
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.445
4fv6E57Mitogen-activated protein kinase 12.7.11.240.445
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.445
4zohFADPutative oxidoreductase FAD-binding subunit/0.445
5dt3ATPAurora kinase A2.7.11.10.445
1h1q2A6Cyclin-dependent kinase 22.7.11.220.444
2j0j4STFocal adhesion kinase 12.7.10.20.444
2vx17X8Ephrin type-B receptor 42.7.10.10.444
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.444
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.444
3r1yX76Cyclin-dependent kinase 22.7.11.220.444
3rk708ZCyclin-dependent kinase 22.7.11.220.444
3rni21ZCyclin-dependent kinase 22.7.11.220.444
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.444
4eop1ROCyclin-dependent kinase 22.7.11.220.444
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.444
4qmpDKISerine/threonine-protein kinase 242.7.11.10.444
5e8wSTUTGF-beta receptor type-12.7.11.300.444
1mqbANPEphrin type-A receptor 22.7.10.10.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.443
2wihP48Cyclin-dependent kinase 22.7.11.220.443
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.443
2xneASHAurora kinase A2.7.11.10.443
3e5aVX6Aurora kinase A2.7.11.10.443
3rk507ZCyclin-dependent kinase 22.7.11.220.443
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.443
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.443
4c3rACPAurora kinase A2.7.11.10.443
4fkr45KCyclin-dependent kinase 22.7.11.220.443
4fmqANPMitogen-activated protein kinase 12.7.11.240.443
4ysjADPCalmodulin-like domain protein kinase/0.443
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.442
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.442
2c6iDT1Cyclin-dependent kinase 22.7.11.220.442
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.442
3a7jADPSerine/threonine-protein kinase 242.7.11.10.442
3ddpRC8Cyclin-dependent kinase 22.7.11.220.442
3ezrEZRCyclin-dependent kinase 22.7.11.220.442
3p5kP5KMitogen-activated protein kinase 14/0.442
4aacAAVMitogen-activated protein kinase 14/0.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1eh4IC1Casein kinase I homolog 12.7.11.10.441
1wvxBD4Death-associated protein kinase 12.7.11.10.441
2b53D23Cyclin-dependent kinase 22.7.11.220.441
2r3iSCFCyclin-dependent kinase 22.7.11.220.441
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.441
3oriAGSSerine/threonine protein kinase/0.441
3r7eX88Cyclin-dependent kinase 22.7.11.220.441
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.441
4wkqIREEpidermal growth factor receptor2.7.10.10.441
5l8jADPAurora kinase A2.7.11.10.441
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.440
1vjy460TGF-beta receptor type-12.7.11.300.440
2c4g514Cyclin-dependent kinase 22.7.11.220.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2puuG2GMitogen-activated protein kinase 14/0.440
2pzpACPFibroblast growth factor receptor 2/0.440
2qoqANPEphrin type-A receptor 32.7.10.10.440
2w05FRTCyclin-dependent kinase 22.7.11.220.440
3bhy7CPDeath-associated protein kinase 3/0.440
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3lfqA28Cyclin-dependent kinase 22.7.11.220.440
3qrsNK8Gag-Pol polyprotein3.4.23.160.440
3r73X87Cyclin-dependent kinase 22.7.11.220.440
3rpv26ZCyclin-dependent kinase 22.7.11.220.440
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4jboWPHAurora kinase A2.7.11.10.440
5dt4ATPAurora kinase A2.7.11.10.440