sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2v5v | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2v5v | FMN | Flavodoxin | / | 1.000 | |
| 1fue | FMN | Flavodoxin | / | 0.514 | |
| 1yob | FMN | Flavodoxin 2 | / | 0.507 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.491 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.486 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 3esy | FMN | Flavodoxin | / | 0.482 | |
| 1l4g | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.480 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.479 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.478 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 2e07 | SAH | Diphthine synthase | / | 0.476 | |
| 1czn | FMN | Flavodoxin | / | 0.475 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.475 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.474 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.474 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.474 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.473 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.472 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.472 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.472 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.472 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.472 | |
| 1l4e | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.471 | |
| 4el0 | D1K | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.471 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.470 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.469 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.469 | |
| 1ofv | FMN | Flavodoxin | / | 0.468 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.468 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.468 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.468 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.468 | |
| 3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.468 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.467 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.466 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.466 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.466 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.465 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 2w5u | FMN | Flavodoxin | / | 0.465 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.465 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.465 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3qfr | NAP | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.465 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.464 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.464 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.463 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.463 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.462 | |
| 1l2o | ADP | Myosin heavy chain, striated muscle | / | 0.462 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1t57 | FMN | Conserved protein | / | 0.462 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.462 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.461 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.461 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3e8x | NAP | BH1520 protein | / | 0.460 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.460 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.460 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.459 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.458 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.458 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.458 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 4h2d | FMN | NADPH-dependent diflavin oxidoreductase 1 | / | 0.458 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.458 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.457 | |
| 1vce | SAH | Diphthine synthase | / | 0.457 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.457 | |
| 3amf | FMN | FMN-binding protein | / | 0.457 | |
| 4egn | TWO | Cytochrome P450 | / | 0.457 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.457 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.456 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1l4f | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.456 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.456 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.456 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1jha | AAM | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.455 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.455 | |
| 1q4w | DQU | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.455 | |
| 1u0h | ONM | Adenylate cyclase type 2 | / | 0.455 | |
| 1u0h | ONM | Adenylate cyclase type 5 | / | 0.455 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.455 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.455 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.454 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.454 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.454 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.454 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.454 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 2dsi | SAH | Diphthine synthase | / | 0.453 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.453 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4ma4 | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.453 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.453 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.452 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.452 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.452 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.452 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.452 | |
| 2ed4 | FAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.452 | |
| 2fcr | FMN | Flavodoxin | / | 0.452 | |
| 2fto | TMP | Thymidylate synthase | / | 0.452 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.452 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4ck2 | NVU | Integrase | / | 0.452 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.451 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.451 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.451 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.451 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.451 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 4cfa | WOP | Integrase | / | 0.451 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.451 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.451 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.450 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2p2x | SAH | Diphthine synthase | / | 0.450 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4cje | Q31 | Integrase | / | 0.450 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.449 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.449 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3b9l | AZZ | Serum albumin | / | 0.448 | |
| 3eey | SAM | rRNA methylase | / | 0.448 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.448 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.448 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.448 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.447 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.447 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.447 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.447 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.447 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.447 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1jmi | UMP | Thymidylate synthase | / | 0.446 | |
| 1lde | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.446 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.446 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.446 | |
| 1vza | UMP | Thymidylate synthase | / | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.446 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.446 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.445 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.445 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.445 | |
| 5cdg | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.444 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1sez | OMN | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.444 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2pch | SAH | Diphthine synthase | / | 0.444 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.444 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.444 | |
| 3ke8 | EIP | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.444 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.444 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.444 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3qfs | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 4bmp | FMN | Protein NrdI | / | 0.444 | |
| 4ceq | QCH | Integrase | / | 0.444 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.444 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.444 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.444 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.444 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.443 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.443 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.443 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.443 | |
| 2dxw | SAH | Diphthine synthase | / | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.443 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 3bnk | FMN | Flavoredoxin | / | 0.443 | |
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 3up0 | D7S | aceDAF-12 | / | 0.443 | |
| 4cjp | 4D2 | Integrase | / | 0.443 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.443 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.443 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4umx | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.443 | |
| 5fx2 | FMN | Flavodoxin | / | 0.443 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.442 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2eeq | SAH | Diphthine synthase | / | 0.442 | |
| 2egs | SAH | Diphthine synthase | / | 0.442 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.442 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 3eku | CY9 | Actin-5C | / | 0.442 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.442 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.442 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.442 | |
| 5jjs | SAH | Genome polyprotein | / | 0.442 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.441 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.441 | |
| 2ejj | SAH | Diphthine synthase | / | 0.441 | |
| 2ejz | SAH | Diphthine synthase | / | 0.441 | |
| 2owu | SAH | Diphthine synthase | / | 0.441 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.441 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.441 | |
| 4cjf | RVN | Integrase | / | 0.441 | |
| 4cjq | VXO | Integrase | / | 0.441 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.441 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.440 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.440 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.440 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2p6d | SAH | Diphthine synthase | / | 0.440 | |
| 2pcm | SAH | Diphthine synthase | / | 0.440 | |
| 2z6r | SAH | Diphthine synthase | / | 0.440 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.440 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.440 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3dzv | ADP | Hydroxyethylthiazole kinase | / | 0.440 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.440 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.440 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.440 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4jwf | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.440 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |