sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2v2q	NVG	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2v2q	NVG	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	1.000
2v2v	V12	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.623
2v34	CTN	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.618
2vf3	GVS	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.563
4emd	C5P	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.524
2v2z	ADP	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.523
2v2z	CDM	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.459
2v8p	ADP	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.449