sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2uyh	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2uyh	SAH	Modification methylase HhaI	2.1.1.37	1.000
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.678
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.670
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.654
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.609
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.608
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.593
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.516
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.493
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.443
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.442