sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rtr | IMI | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2rtr | IMI | Streptavidin | / | 1.000 | |
| 2rtq | IMI | Streptavidin | / | 0.765 | |
| 1swt | BTN | Streptavidin | / | 0.659 | |
| 2rtg | BTN | Streptavidin | / | 0.657 | |
| 1srj | NAB | Streptavidin | / | 0.652 | |
| 1lcw | SHM | Streptavidin | / | 0.651 | |
| 2izh | BTN | Streptavidin | / | 0.651 | |
| 1i9h | BNI | Streptavidin | / | 0.650 | |
| 2rtd | BTN | Streptavidin | / | 0.646 | |
| 3ry2 | BTN | Streptavidin | / | 0.646 | |
| 1mk5 | BTN | Streptavidin | / | 0.640 | |
| 1srh | MOB | Streptavidin | / | 0.637 | |
| 2rtf | BTN | Streptavidin | / | 0.634 | |
| 2rto | IMI | Streptavidin | / | 0.632 | |
| 2rtp | IMI | Streptavidin | / | 0.627 | |
| 2izg | BTN | Streptavidin | / | 0.624 | |
| 2rti | GLL | Streptavidin | / | 0.622 | |
| 1sri | DMB | Streptavidin | / | 0.620 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.617 | |
| 2izk | GLL | Streptavidin | / | 0.617 | |
| 3wzn | BTN | Streptavidin | / | 0.617 | |
| 2rtk | GLL | Streptavidin | / | 0.616 | |
| 1srg | MHB | Streptavidin | / | 0.615 | |
| 2izl | IMI | Streptavidin | / | 0.613 | |
| 2rtn | IMI | Streptavidin | / | 0.613 | |
| 1srf | MTB | Streptavidin | / | 0.609 | |
| 2rte | BTN | Streptavidin | / | 0.609 | |
| 4bx7 | B4F | Streptavidin | / | 0.609 | |
| 4dne | DTB | Streptavidin | / | 0.606 | |
| 1sre | HAB | Streptavidin | / | 0.601 | |
| 2y3f | BTN | Streptavidin | / | 0.600 | |
| 2izf | BTN | Streptavidin | / | 0.594 | |
| 4gda | BTN | Streptavidin | / | 0.586 | |
| 1luq | BTN | Streptavidin | / | 0.583 | |
| 1lcz | BH7 | Streptavidin | / | 0.582 | |
| 1rxh | BNI | Streptavidin | / | 0.581 | |
| 1swp | BTQ | Streptavidin | / | 0.580 | |
| 1df8 | BTN | Streptavidin | / | 0.579 | |
| 3wyq | BTN | Streptavidin | / | 0.576 | |
| 1mep | BTN | Streptavidin | / | 0.573 | |
| 1stp | BTN | Streptavidin | / | 0.569 | |
| 2izj | BTN | Streptavidin | / | 0.569 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.566 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.565 | |
| 3rdq | DTB | Streptavidin | / | 0.565 | |
| 2rtm | IMI | Streptavidin | / | 0.564 | |
| 2izi | BTN | Streptavidin | / | 0.563 | |
| 4z28 | BTN | Hoefavidin | / | 0.563 | |
| 2avi | BTN | Avidin | / | 0.561 | |
| 2c4i | BTN | Avidin | / | 0.555 | |
| 2uyw | BTN | Avd protein | / | 0.553 | |
| 1swe | BTN | Streptavidin | / | 0.551 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.550 | |
| 2uz2 | BTN | Avd protein | / | 0.539 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.534 | |
| 2zsc | BTN | Tamavidin2 | / | 0.532 | |
| 1avd | BTN | Avidin | / | 0.530 | |
| 4gd9 | BTN | Streptavidin | / | 0.530 | |
| 1nc9 | IMI | Streptavidin | / | 0.528 | |
| 1swn | BTN | Streptavidin | / | 0.527 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.516 | |
| 1ndj | BTN | Streptavidin | / | 0.514 | |
| 4bj8 | BTN | Avidin | / | 0.501 | |
| 3wyp | BSO | Streptavidin | / | 0.500 | |
| 1n9m | BTN | Streptavidin | / | 0.499 | |
| 2kce | D16 | Thymidylate synthase | / | 0.497 | |
| 4yvb | BTN | Streptavidin | / | 0.494 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.490 | |
| 1xp8 | AGS | Protein RecA | / | 0.490 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.488 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.486 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.486 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.486 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.485 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.484 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.484 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.484 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.482 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.482 | |
| 3up0 | D7S | aceDAF-12 | / | 0.482 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.480 | |
| 2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.479 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.479 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.478 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.478 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.477 | |
| 2jgs | BTN | Avidin | / | 0.477 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.477 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.477 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.477 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.476 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.474 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.473 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 2ow9 | SP6 | Collagenase 3 | 3.4.24 | 0.473 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.473 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.473 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.473 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.473 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.472 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.472 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.472 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.471 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.471 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.471 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.470 | |
| 1swd | BTN | Streptavidin | / | 0.470 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.470 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.470 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.470 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.470 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.470 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.470 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.469 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.469 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.468 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.468 | |
| 1lke | DOG | Bilin-binding protein | / | 0.468 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1t57 | FMN | Conserved protein | / | 0.468 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.468 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.468 | |
| 3vgw | NVZ | Avidin | / | 0.468 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.468 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.468 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.467 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.467 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.467 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.467 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.467 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.466 | |
| 1lqa | NDP | Protein tas | / | 0.466 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.466 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.465 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.465 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.465 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.465 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.464 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.464 | |
| 2r8o | T5X | Transketolase 1 | / | 0.464 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.464 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2ewn | BTX | Bifunctional ligase/repressor BirA | / | 0.463 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.463 | |
| 4kxj | P34 | Nucleoprotein | / | 0.463 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.463 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.463 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.462 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.462 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.462 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.462 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.462 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.461 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.461 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.461 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.461 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.461 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.460 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.460 | |
| 2fto | TMP | Thymidylate synthase | / | 0.460 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.460 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.460 | |
| 3ehj | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.460 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.460 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.460 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.459 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.459 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.458 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.458 | |
| 3b9l | AZZ | Serum albumin | / | 0.458 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 3up3 | XCA | aceDAF-12 | / | 0.458 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.458 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.458 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4xcz | T3Q | Qdtf | / | 0.458 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.458 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.457 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.457 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.457 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.457 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.457 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.457 | |
| 3v49 | PK0 | Androgen receptor | / | 0.457 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.457 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.457 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.457 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.456 | |
| 1r2j | FAD | FkbI | / | 0.456 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.456 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.456 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.456 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.456 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.456 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.456 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.455 | |
| 2a5c | 8DA | Avidin | / | 0.455 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.455 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.455 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.455 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.455 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.454 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.454 | |
| 2r8p | T6F | Transketolase 1 | / | 0.454 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.454 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.454 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.454 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.454 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.453 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.453 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.453 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2rtl | IMI | Streptavidin | / | 0.453 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.453 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.453 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.453 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.452 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.452 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.452 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.452 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.452 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.452 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.452 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.452 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.452 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.452 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.451 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.451 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.451 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.451 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.451 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.451 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.451 | |
| 4xd1 | T3Q | Qdtf | / | 0.451 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1fml | RTL | Retinol dehydratase | / | 0.450 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.450 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.450 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.450 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.450 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.450 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.449 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.449 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.449 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.449 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.449 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.449 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.449 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.449 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.449 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.449 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.449 | |
| 4kwh | NAP | Reductase homolog | / | 0.449 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.449 | |
| 4yp5 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.449 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.449 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.448 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1s36 | CEI | Obelin | / | 0.448 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.448 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.448 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 2hzq | STR | Apolipoprotein D | / | 0.448 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.448 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.448 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.448 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.448 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.448 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.448 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.448 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.448 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.448 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.448 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.447 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.447 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.447 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.447 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.447 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.447 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.447 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.447 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.447 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.447 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.447 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.447 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.447 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.446 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.446 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.446 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.446 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.446 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.446 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.446 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.446 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.446 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.446 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.446 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.446 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.446 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 0.446 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.446 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.445 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.445 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.445 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.445 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.445 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 3e8x | NAP | BH1520 protein | / | 0.445 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.445 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.445 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.445 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.445 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.445 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.445 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.444 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.444 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.444 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.444 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.444 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.444 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.444 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.444 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.444 | |
| 5jr3 | 4MU | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.444 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.443 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.443 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.443 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.443 | |
| 1tys | TMP | Thymidylate synthase | / | 0.443 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.443 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.443 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.443 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.443 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.443 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.443 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.443 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.442 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.442 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.442 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.442 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.442 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.442 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.442 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.442 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4iah | 1DX | Alr2278 protein | / | 0.442 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.442 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.441 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.441 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.441 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.441 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.441 | |
| 2vro | NDP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.441 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.441 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3keo | NAD | Redox-sensing transcriptional repressor Rex | / | 0.441 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.441 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.441 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.441 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4pd6 | URI | Nucleoside permease | / | 0.441 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.440 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.440 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3ms5 | REE | Gamma-butyrobetaine dioxygenase | 1.14.11.1 | 0.440 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.440 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.440 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.440 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.440 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.440 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4e5m | NAP | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4er7 | AW3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.440 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.440 | |
| 4h6p | FMN | Chromate reductase | / | 0.440 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.440 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.440 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.440 |