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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2rtoIMIStreptavidin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2rtoIMIStreptavidin/1.000
2rtfBTNStreptavidin/0.779
2izhBTNStreptavidin/0.773
2rtiGLLStreptavidin/0.727
2rtgBTNStreptavidin/0.686
2izgBTNStreptavidin/0.679
1lcwSHMStreptavidin/0.671
1sreHABStreptavidin/0.666
2izkGLLStreptavidin/0.665
4bx7B4FStreptavidin/0.660
4gdaBTNStreptavidin/0.657
2rtdBTNStreptavidin/0.649
2izlIMIStreptavidin/0.645
3ry2BTNStreptavidin/0.645
1srfMTBStreptavidin/0.639
1sriDMBStreptavidin/0.639
4dneDTBStreptavidin/0.634
1i9hBNIStreptavidin/0.633
1mk5BTNStreptavidin/0.633
2rtrIMIStreptavidin/0.631
1srhMOBStreptavidin/0.629
1srjNABStreptavidin/0.629
2iziBTNStreptavidin/0.627
2y3fBTNStreptavidin/0.627
1srgMHBStreptavidin/0.626
1stpBTNStreptavidin/0.624
2rtkGLLStreptavidin/0.624
3wyqBTNStreptavidin/0.624
2fhnBNIAvidin-related protein 4/5/0.622
2rtpIMIStreptavidin/0.622
2izfBTNStreptavidin/0.614
1rxhBNIStreptavidin/0.612
2rteBTNStreptavidin/0.610
2rtnIMIStreptavidin/0.609
1df8BTNStreptavidin/0.602
3wznBTNStreptavidin/0.602
1swtBTNStreptavidin/0.601
1lczBH7Streptavidin/0.595
1luqBTNStreptavidin/0.595
2rtqIMIStreptavidin/0.595
2izjBTNStreptavidin/0.593
2aviBTNAvidin/0.590
3rdqDTBStreptavidin/0.585
2c4iBTNAvidin/0.584
2rtmIMIStreptavidin/0.569
4bcsBTNAvidin-related protein 4/5/0.562
2fhlBNIAvidin-related protein 4/5/0.559
1y52BTNAvidin-related protein 4/5/0.558
1avdBTNAvidin/0.549
1swpBTNStreptavidin/0.545
2zscBTNTamavidin2/0.536
3ew2BTNHypothetical conserved protein/0.536
2uz2BTNAvd protein/0.535
3t2wBTNAvidin/streptavidin/0.528
1swpBTQStreptavidin/0.520
2uywBTNAvd protein/0.514
1swnBTNStreptavidin/0.508
5iqdGNPBifunctional AAC/APH2.3.10.507
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.505
1kziTHGThymidylate synthase/0.505
1n9mBTNStreptavidin/0.505
1nc9IMIStreptavidin/0.504
4z28BTNHoefavidin/0.502
3c3xNAPEugenol synthase 11.1.1.3180.501
1sweBTNStreptavidin/0.498
1wsvTHHAminomethyltransferase, mitochondrial/0.497
3nr4PYVAbscisic acid receptor PYL2/0.497
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
2x9dITCTetracycline repressor protein class D/0.496
3dds26BGlycogen phosphorylase, liver form2.4.1.10.496
3wypBSOStreptavidin/0.496
4gevCB3Thymidylate synthase/0.496
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.495
1m78NDPDihydrofolate reductase1.5.1.30.493
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.492
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.492
1jtqLY3Thymidylate synthase/0.491
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.491
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.491
1kt6RTLRetinol-binding protein 4/0.490
3d4bDZDNAD-dependent protein deacetylase/0.490
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.490
2zjwREFCasein kinase II subunit alpha2.7.11.10.489
4o71CPBBromodomain-containing protein 4/0.489
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.489
1pq944BOxysterols receptor LXR-beta/0.488
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.488
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
4bb3KKAIsopenicillin N synthase1.21.3.10.488
4l64C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase2.1.1.140.488
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.488
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.485
1nw6SFGModification methylase RsrI2.1.1.720.484
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.484
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
4a8v2ANMajor pollen allergen Bet v 1-J/0.484
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.483
1ndjBTNStreptavidin/0.483
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.483
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.483
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.482
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.481
3w5rLOAVitamin D3 receptor/0.481
1mvtDTMDihydrofolate reductase1.5.1.30.480
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
2z3uCRRCytochrome P450/0.480
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.480
4jq4IMNAldo-keto reductase family 1 member C2/0.480
5eccNAPDehydrofolate reductase type I/0.480
1qjfACSIsopenicillin N synthase1.21.3.10.479
1tojHCIAspartate aminotransferase2.6.1.10.479
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.479
4kko1REGag-Pol polyprotein2.7.7.490.479
2bfmTOPPteridine reductase 11.5.1.330.478
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.478
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.478
4twnB96Ephrin type-A receptor 32.7.10.10.478
5iqeGNPBifunctional AAC/APH2.3.10.478
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
2hcdBIVVitamin D3 receptor A/0.477
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.477
4dliIRGMitogen-activated protein kinase 14/0.477
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.477
4ez8DHFThymidylate synthase2.1.1.450.477
1axwMTXThymidylate synthase/0.476
1dnaCB3Thymidylate synthase/0.476
1ia1NDPDihydrofolate reductase1.5.1.30.476
1j9zFADNADPH--cytochrome P450 reductase/0.476
1xp8AGSProtein RecA/0.476
2a5c8DAAvidin/0.476
4bfuZVUPantothenate kinase2.7.1.330.476
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4mryCEIObelin/0.476
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
1nceCB3Thymidylate synthase/0.475
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.475
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.475
1rx8FOLDihydrofolate reductase1.5.1.30.475
2tscCB3Thymidylate synthase/0.475
2y6fM9FIsopenicillin N synthase1.21.3.10.475
3d7zGK5Mitogen-activated protein kinase 14/0.475
3d84NDPDihydrofolate reductase1.5.1.30.475
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.475
3up3XCAaceDAF-12/0.475
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.474
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.474
1o5rFR9Adenosine deaminase3.5.4.40.474
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.474
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.474
3elm24FCollagenase 33.4.240.474
4o95245Cytokinin dehydrogenase 4/0.474
1aoeGW3Dihydrofolate reductase1.5.1.30.473
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.473
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.473
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.473
3c14FOKAdenylate cyclase type 2/0.473
3c14FOKAdenylate cyclase type 5/0.473
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.473
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
1obnASVIsopenicillin N synthase1.21.3.10.472
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.472
1u54ACPActivated CDC42 kinase 1/0.472
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.472
2vcmM11Isopenicillin N synthase1.21.3.10.472
3juqAKDPhenazine biosynthesis protein A/B/0.472
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.472
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.472
4g090VDHistidinol dehydrogenase/0.472
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.472
5iqbGNPBifunctional AAC/APH2.3.10.472
1lf3EH5Plasmepsin-23.4.23.390.471
1z6tADPApoptotic protease-activating factor 1/0.471
2zevB71Geranylgeranyl pyrophosphate synthase/0.471
3gxfIFMGlucosylceramidase3.2.1.450.471
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.471
4rrgA3TThreonine--tRNA ligase6.1.1.30.471
5iqaGNPBifunctional AAC/APH2.3.10.471
1b3dS27Stromelysin-13.4.24.170.470
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
2bbqPFGThymidylate synthase/0.470
2op18PCEnoyl-ACP reductase/0.470
2qvdBERBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.470
4rtsSAMDNA adenine methylase2.1.1.720.470
1tduDURThymidylate synthase/0.469
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.469
2jgsBTNAvidin/0.469
2vbpVB1Isopenicillin N synthase1.21.3.10.469
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.469
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.469
4ap3FADSteroid monooxygenase/0.469
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.469
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4fqsLYAThymidylate synthase ThyA/0.469
4knzCB3Thymidylate synthase/0.469
4pnmNU1Tankyrase-22.4.2.300.469
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.469
1hb1OCVIsopenicillin N synthase1.21.3.10.468
1lkeDOGBilin-binding protein/0.468
1ly4COQDihydrofolate reductase1.5.1.30.468
1mrqSTRAldo-keto reductase family 1 member C1/0.468
1o6qR17Squalene--hopene cyclase4.2.1.1290.468
1upw444Oxysterols receptor LXR-beta/0.468
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.468
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.468
2rtlIMIStreptavidin/0.468
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.468
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.468
4g1z0VPVitamin D3 receptor A/0.468
4gbeSAHDNA adenine methylase2.1.1.720.468
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.467
1fwkADPHomoserine kinase2.7.1.390.467
1h51FMNPentaerythritol tetranitrate reductase/0.467
1rftPXMPyridoxal kinase2.7.1.350.467
1s3vTQDDihydrofolate reductase1.5.1.30.467
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.467
3pe2E1BCasein kinase II subunit alpha2.7.11.10.467
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.467
4b1rITCTetracycline repressor protein class D/0.467
8catNDPCatalase1.11.1.60.467
1egcCO8Medium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.466
1h36R88Squalene--hopene cyclase4.2.1.1290.466
2ftoCB3Thymidylate synthase/0.466
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.466
2zlaVDBVitamin D3 receptor/0.466
3mb714ICasein kinase II subunit alpha2.7.11.10.466
3vtdTKDVitamin D3 receptor/0.466
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
5e8wSTUTGF-beta receptor type-12.7.11.300.466
1swdBTNStreptavidin/0.465
2tohHBITyrosine 3-monooxygenase1.14.16.20.465
2w9hTOPDihydrofolate reductase1.5.1.30.465
2zevIPEGeranylgeranyl pyrophosphate synthase/0.465
3qlrNDPDihydrofolate reductase1.5.1.30.465
4fhd0TTSpore photoproduct lyase/0.465
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.465
4k6fNAPPutative Acetoacetyl-CoA reductase/0.465
4rrfA3SThreonine--tRNA ligase6.1.1.30.465
4rrxLURProstaglandin G/H synthase 21.14.99.10.465
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.465
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.465
1bwlFMNNADPH dehydrogenase 11.6.99.10.464
1jpaANPEphrin type-B receptor 22.7.10.10.464
1mepBTNStreptavidin/0.464
1oc1ASVIsopenicillin N synthase1.21.3.10.464
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.464
1tj1FADBifunctional protein PutA1.5.5.20.464
2fzjDH3Dihydrofolate reductase1.5.1.30.464
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.464
3lkhLT6Genome polyprotein2.7.7.480.464
3mb601ICasein kinase II subunit alpha2.7.11.10.464
3up0D7SaceDAF-12/0.464
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.464
4qzuRTLRetinol-binding protein 2/0.464
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.464
4yvbBTNStreptavidin/0.464
3sn6P0GBeta-2 adrenergic receptor/0.464
1bxqPP8Penicillopepsin-13.4.23.200.463
1ezfIN0Squalene synthase2.5.1.210.463
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.463
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.463
2ftoTMPThymidylate synthase/0.463
2fznFADBifunctional protein PutA1.5.5.20.463
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.463
3tq8TOPDihydrofolate reductase/0.463
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.463
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.463
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4uofDATNucleoside diphosphate kinase/0.463
1cdeGARPhosphoribosylglycinamide formyltransferase/0.462
1fvpFMANon-fluorescent flavoprotein/0.462
1h35R01Squalene--hopene cyclase4.2.1.1290.462
2harOCCVitamin D3 receptor/0.462
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
2ofv242Tyrosine-protein kinase Lck2.7.10.20.462
3arvSAUChitinase A/0.462
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
3owsEQUSteroid Delta-isomerase5.3.3.10.462
3t8vBTJM1 family aminopeptidase3.4.110.462
4bquCLRJapanin/0.462
4c02TAKActivin receptor type-12.7.11.300.462
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4jlk1NODeoxycytidine kinase2.7.1.740.462
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.462
4rnxFMNNADPH dehydrogenase 11.6.99.10.462
5cb3APRO-acetyl-ADP-ribose deacetylase/0.462
5iua6DXAdenosine receptor A2a/0.462
1jlaTNKGag-Pol polyprotein2.7.7.490.461
1kquBR4Phospholipase A2, membrane associated/0.461
1o2g696Prothrombin3.4.21.50.461
1pd9CO4Dihydrofolate reductase1.5.1.30.461
1zdwFLVPrenyltransferase/0.461
2ea1GPGRibonuclease I3.1.27.60.461
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2he5NDPAldo-keto reductase family 1 member C211.1.10.461
2mjpANPdITP/XTP pyrophosphatase3.6.1.190.461
2wo7ASVIsopenicillin N synthase1.21.3.10.461
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
3pd4A3GThreonine--tRNA ligase6.1.1.30.461
4oztP1AEcdysone receptor, putative/0.461
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.460
1d2sDHTSex hormone-binding globulin/0.460
1tj2FADBifunctional protein PutA1.5.5.20.460
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1yhjR6CPyridoxal kinase2.7.1.350.460
1yimCM4Estrogen receptor/0.460
2ociTYCValacyclovir hydrolase3.10.460
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.460
2xlrFADPutative flavin-containing monooxygenase/0.460
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.460
3fo7IMNPhospholipase A2 VRV-PL-VIIIa/0.460
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3ganSVRProtein RDM1/0.460
3nx2FERFerulic acid decarboxylase/0.460
3r0tFU9Casein kinase II subunit alpha2.7.11.10.460
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.460
1ldqSHMAvidin/0.459
1osvCHCBile acid receptor/0.459
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.459
2bxmIMNSerum albumin/0.459
2cdaNAPGlucose 1-dehydrogenase/0.459
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.459
2xtbKRMAdenosine kinase, putative/0.459
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.459
3owj1ELCasein kinase II subunit alpha2.7.11.10.459
3v0tATRPerakine reductase1.1.1.3170.459
4aoxFADSteroid monooxygenase/0.459
4bj8BTNAvidin/0.459
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.459
4olfHFGProline--tRNA ligase6.1.1.150.459
4uyg73BBromodomain-containing protein 2/0.459
4v2gITCTetracycline repressor protein class D/0.459
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.459
1c3eGARPhosphoribosylglycinamide formyltransferase/0.458
1e92HBIPteridine reductase 11.5.1.330.458
1n5qTNCActVA 6 protein/0.458
1qknRALEstrogen receptor beta/0.458
2bu9HFVIsopenicillin N synthase1.21.3.10.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3gwfFADCyclohexanone monooxygenase/0.458
3h3sH15Collagen type IV alpha-3-binding protein/0.458
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3p1799PProthrombin3.4.21.50.458
3vf60H6Glucokinase2.7.1.20.458
3w78CBDFMN-dependent NADH-azoreductase/0.458
4a2aATPCell division protein FtsA/0.458
4b4w9L9Bifunctional protein FolD/0.458
4bfyZVYPantothenate kinase2.7.1.330.458
4iyg1HUStrictosidine synthase4.3.3.20.458
4jhiEMUNodulin-13/0.458
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4mv4ACPBiotin carboxylase6.3.4.140.458
4q0kGA3Phytohormone-binding protein/0.458
5bylGCPBifunctional AAC/APH2.3.10.458
1ci7UMPThymidylate synthase2.1.1.450.457
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1phhFADp-hydroxybenzoate hydroxylase/0.457
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
2hamC33Vitamin D3 receptor/0.457
2hvdADPNucleoside diphosphate kinase A2.7.4.60.457
2r6jNDPEugenol synthase 11.1.1.3180.457
2vmyFFOSerine hydroxymethyltransferase/0.457
3q5pTACMultidrug-efflux transporter 1 regulator/0.457
4dpy2P0Mevalonate diphosphate decarboxylase/0.457
4ia3BIVVitamin D3 receptor A/0.457
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4o8aFADBifunctional protein PutA1.2.1.880.457
4psbGA3Cytokinin-specific binding protein/0.457
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.457
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.457
5iqhGNPBifunctional AAC/APH2.3.10.457
1blzACVIsopenicillin N synthase1.21.3.10.456
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1qoqIGPTryptophan synthase alpha chain/0.456
1s6qTPBGag-Pol polyprotein2.7.7.490.456
2a2sGSNGlutathione S-transferase P2.5.1.180.456
2hl2SSAThreonine--tRNA ligase6.1.1.30.456
2r2mI50Prothrombin3.4.21.50.456
2yk2YJWHeat shock protein HSP 90-alpha/0.456
3csdEMOPutative ketoacyl reductase1.3.10.456
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3fr5I4AFatty acid-binding protein, adipocyte/0.456
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.456
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3zkyWT4Isopenicillin N synthase1.21.3.10.456
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.456
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.456
4l9q9TPSerum albumin/0.456
4rtkSAHDNA adenine methylase2.1.1.720.456
4zwpM44Xaa-Pro dipeptidase3.4.13.90.456
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.456
1fkxPRHAdenosine deaminase3.5.4.40.455
1hvyD16Thymidylate synthase2.1.1.450.455
1uzwCDHIsopenicillin N synthase1.21.3.10.455
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.455
1zprCB3Thymidylate synthase/0.455
2bfpH4BPteridine reductase 11.5.1.330.455
2hziJINTyrosine-protein kinase ABL12.7.10.20.455
2pksG44Prothrombin3.4.21.50.455
2rhrEMOPutative ketoacyl reductase1.3.10.455
2vprTDCTetracycline repressor protein class H/0.455
3h4vNAPPteridine reductase 11.5.1.330.455
3vt3VDXVitamin D3 receptor/0.455
3znqSS8D-amino-acid oxidase1.4.3.30.455
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.455
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.455
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1crbRTLRetinol-binding protein 1/0.454
1nw5SAMModification methylase RsrI2.1.1.720.454
1wxyFRKAdenosine deaminase3.5.4.40.454
1x2hLPALipoate-protein ligase A6.3.1.200.454
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2iygFMNAppA, antirepressor of ppsR, sensor of blue light/0.454
2jf9OHTEstrogen receptor/0.454
2on6IMHPurine nucleoside phosphorylase2.4.2.10.454
2tpsTPSThiamine-phosphate synthase/0.454
2vg7NNIGag-Pol polyprotein2.7.7.490.454
2xrlDXTTetracycline repressor protein class D/0.454
2ydoADNAdenosine receptor A2a/0.454
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.454
3gqoAPRNon-structural polyprotein/0.454
3nga3NGCasein kinase II subunit alpha2.7.11.10.454
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4cdmFO1Deoxyribodipyrimidine photolyase/0.454
4cukNAID-lactate dehydrogenase/0.454
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.454
4ivrN50Thymidine kinase/0.454
4plpNADHomospermidine synthase2.5.1.440.454
3pblETQD(3) dopamine receptor/0.454
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.453
1kceCB3Thymidylate synthase/0.453
1lqaNDPProtein tas/0.453
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.453
1q23FUAChloramphenicol acetyltransferase2.3.1.280.453
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.453
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.453
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.453
2npfMOUElongation factor 2/0.453
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2qx7NAPEugenol synthase 11.1.1.3180.453
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.453
2xlpFADPutative flavin-containing monooxygenase/0.453
3biy01KHistone acetyltransferase p300/0.453
3eksCY9Actin-5C/0.453
3h3r14HCollagen type IV alpha-3-binding protein/0.453
3ntz3TZDihydrofolate reductase1.5.1.30.453
3tk3CPZCytochrome P450 2B41.14.14.10.453
3w8wFADPutative FAD-dependent oxygenase EncM/0.453
4gg50J3Hepatocyte growth factor receptor2.7.10.10.453
4jq8KJ8Epidermal growth factor receptor2.7.10.10.453
4k5o1OTM1 family aminopeptidase3.4.110.453
4l0qNADAlcohol dehydrogenase class-3/0.453
4tjy3GNTankyrase-22.4.2.300.453
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.453
1dr5NAPDihydrofolate reductase1.5.1.30.452
1drhNAPDihydrofolate reductase1.5.1.30.452
1dtpAPUDiphtheria toxin/0.452
1nhkCMPNucleoside diphosphate kinase2.7.4.60.452
1trkTPPTransketolase 12.2.1.10.452
1uyePU9Heat shock protein HSP 90-alpha/0.452
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
2w3bNDPDihydrofolate reductase1.5.1.30.452
2x7gPVBSRSF protein kinase 22.7.11.10.452
3bgxMEFThymidylate synthase/0.452
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.452
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.452
3nwlNDPCatalase1.11.1.60.452
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.452
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.452
4i8vBHFCytochrome P450 1A11.14.14.10.452
4m6l21VDihydrofolate reductase1.5.1.30.452
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.452
5g53NECAdenosine receptor A2a/0.452
5jtbZMAAdenosine receptor A2a/0.452
3emlZMAAdenosine receptor A2a/0.452
1e2nRCAThymidine kinase/0.451
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.451
1ohkCOPDihydrofolate reductase1.5.1.30.451
1opbRETRetinol-binding protein 2/0.451
1orhSAHProtein arginine N-methyltransferase 1/0.451
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1vj3TABDihydrofolate reductase1.5.1.30.451
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.451
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.451
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.451
2zbaZBATrichothecene 3-O-acetyltransferase/0.451
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.451
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3i2834NBifunctional epoxide hydrolase 23.3.2.100.451
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.451
3mytEQUSteroid Delta-isomerase5.3.3.10.451
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.451
3r96ACOMccE protein/0.451
3v76FDAUncharacterized protein/0.451
3vgnFNNSteroid Delta-isomerase5.3.3.10.451
4c6zTLE3-oxoacyl-ACP synthase/0.451
4e37NDPCatalase1.11.1.60.451
4eiyZMAAdenosine receptor A2a/0.451
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.451
4j7uYTZSepiapterin reductase1.1.1.1530.451
4m9aFDAAcyl-CoA dehydrogenase/0.451
4mxeACON-acetyltransferase ESCO12.3.10.451
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.451
5cmx0G6Prothrombin3.4.21.50.451
1hnvTBOGag-Pol polyprotein2.7.7.490.450
1kt7RTLRetinol-binding protein 4/0.450
1qiqACCIsopenicillin N synthase1.21.3.10.450
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.450
2cahNDPCatalase1.11.1.60.450
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2j9gADPBiotin carboxylase6.3.4.140.450
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.450
2r0pK2CPutative FAD-monooxygenase/0.450
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3a783EVVitamin D3 receptor/0.450
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.450
3kpzZNEVitamin D3 receptor/0.450
3ns2PYVAbscisic acid receptor PYL2/0.450
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.450
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.450
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.450
3w0hW12Vitamin D3 receptor/0.450
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.450
4ceqQCHIntegrase/0.450
4jlj1NMDeoxycytidine kinase2.7.1.740.450
4rtoSFGDNA adenine methylase2.1.1.720.450
4ruoBIVVitamin D3 receptor A/0.450
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.450
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.450
3qakUKAAdenosine receptor A2a/0.450
1dgfNDPCatalase1.11.1.60.449
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1iiuRTLRetinol-binding protein 4/0.449
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1qxlFR8Adenosine deaminase3.5.4.40.449
1s9eADBGag-Pol polyprotein2.7.7.490.449
2abbFMNPentaerythritol tetranitrate reductase/0.449
2gjlFMNNitronate monooxygenase1.13.12.160.449
2uuk897Prothrombin3.4.21.50.449
2xlsFADPutative flavin-containing monooxygenase/0.449
2yxuATPPyridoxal kinase2.7.1.350.449
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.449
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.449
3fhxPLPPyridoxal kinase2.7.1.350.449
3gkjHC3Niemann-Pick C1 protein/0.449
3h4vDVPPteridine reductase 11.5.1.330.449
3ie3N11Glutathione S-transferase P2.5.1.180.449
3p62FMNPentaerythritol tetranitrate reductase/0.449
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.449
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.449
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
4ap1NAPSteroid monooxygenase/0.449
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.449
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.449
4c73TLH3-oxoacyl-ACP synthase/0.449
4g2fC07Ephrin type-A receptor 32.7.10.10.449
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.449
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.449
4jzr4JREgl nine homolog 1/0.449
4mv8ACPBiotin carboxylase6.3.4.140.449
4qa2SHHHistone deacetylase 83.5.1.980.449
4tvbNADHomospermidine synthase2.5.1.440.449
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.449
1ia4TQ6Dihydrofolate reductase1.5.1.30.448
1kt3RTLRetinol-binding protein 4/0.448
1lf2R37Plasmepsin-23.4.23.390.448
1trgCB3Thymidylate synthase/0.448
1umlFR4Adenosine deaminase3.5.4.40.448
1wklATPNucleoside diphosphate kinase/0.448
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.448
2bf7HBIPteridine reductase 11.5.1.330.448
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.448
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.448
2gvdFKPAdenylate cyclase type 2/0.448
2gvdFKPAdenylate cyclase type 5/0.448
2j6xFMNLactate oxidase/0.448
2qw8NAPEugenol synthase 11.1.1.3180.448
2uxoTACHTH-type transcriptional regulator TtgR/0.448
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3c1kT15Prothrombin3.4.21.50.448
3cqeP91Wee1-like protein kinase2.7.10.20.448
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.448
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.448
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3lqfNADGalactitol dehydrogenase/0.448
3nguADPNucleoside diphosphate kinase/0.448
3nj0PYVAbscisic acid receptor PYL2/0.448
3nmpPYVAbscisic acid receptor PYL2/0.448
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.448
3qlwN22Dihydrofolate reductase1.5.1.30.448
3vtbTKAVitamin D3 receptor/0.448
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.448
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.448
4er7AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.448
4iarERM5-hydroxytryptamine receptor 1B/0.448
4orkGDPBifunctional AAC/APH2.3.10.448
4prxADPDNA gyrase subunit B/0.448
4rrqA3SThreonine--tRNA ligase6.1.1.30.448
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.448
5iqiGNPBifunctional AAC/APH2.3.10.448
1dhfFOLDihydrofolate reductase1.5.1.30.447
1hniAAAGag-Pol polyprotein2.7.7.490.447
1ia2TQ4Dihydrofolate reductase1.5.1.30.447
1ie9VDXVitamin D3 receptor/0.447
1ikyMSDGag-Pol polyprotein2.7.7.490.447
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.447
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.447
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.447
1v7aFRCAdenosine deaminase3.5.4.40.447
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.447
1zrzBI1Protein kinase C iota type2.7.11.130.447
2b1z17MEstrogen receptor/0.447
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2jdcCAOProbable acetyltransferase/0.447
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.447
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3bnkFMNFlavoredoxin/0.447
3gyf51PDihydrofolate reductase1.5.1.30.447
3h3t16HCollagen type IV alpha-3-binding protein/0.447
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3p8iFMNPentaerythritol tetranitrate reductase/0.447
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.447
3ql3FOLDihydrofolate reductase1.5.1.30.447
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3w0gW07Vitamin D3 receptor/0.447
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.447
4a83DXCMajor pollen allergen Bet v 1-A/0.447
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.447
4b3aTACTetracycline repressor protein class D/0.447
4dieC5PCytidylate kinase/0.447
4do30LAFatty-acid amide hydrolase 13.5.1.990.447
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.447
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.447
4othDRNSerine/threonine-protein kinase N1/0.447
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.447
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.447
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.447
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.447
5fkkTDCTetracycline repressor protein class D/0.447
5irnADPNucleotide binding oligomerization domain containing 2/0.447
1bk0ACVIsopenicillin N synthase1.21.3.10.446
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
1db48INPhospholipase A2, membrane associated/0.446
1drbMTXDihydrofolate reductase1.5.1.30.446
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1fmjRTLRetinol dehydratase/0.446
1gj5130Prothrombin3.4.21.50.446
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.446
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.446
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1ndzFR5Adenosine deaminase3.5.4.40.446
1nm6L86Prothrombin3.4.21.50.446
1s0zEB1Vitamin D3 receptor/0.446
1tduCB3Thymidylate synthase/0.446
1ygjRMCPyridoxal kinase2.7.1.350.446
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.446
2bdyUNBProthrombin3.4.21.50.446
2bxoOPBSerum albumin/0.446
2c3p1TPPyruvate synthase/0.446
2culFADGidA-related protein/0.446
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.446
2ejzSAHDiphthine synthase/0.446
2wdqCBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.446
2wdqCBESuccinate dehydrogenase cytochrome b556 subunit/0.446
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
2x6o2TCTetracycline repressor protein class D/0.446
2xvv9DNSerum albumin/0.446
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.446
3bw4FMNPutative 2-nitropropane dioxygenase/0.446
3ctj320Hepatocyte growth factor receptor2.7.10.10.446
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.446
3koo24DBifunctional epoxide hydrolase 23.3.2.100.446
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.446
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.446
4bj9UHBTankyrase-22.4.2.300.446
4g1y0VOVitamin D3 receptor A/0.446
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4ggzBTNBll1558 protein/0.446
4h9614QDihydrofolate reductase1.5.1.30.446
4kxjP34Nucleoprotein/0.446
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.446
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
4xivADPChemotaxis protein CheA2.7.13.30.446
4mqt2CUMuscarinic acetylcholine receptor M2/0.446
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.445
1d3dBZTProthrombin3.4.21.50.445
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.445
1jtuLYBThymidylate synthase/0.445
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1ludTRRDihydrofolate reductase1.5.1.30.445
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.445
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.445
1t7o152Carnitine O-acetyltransferase2.3.1.70.445
1toiHCIAspartate aminotransferase2.6.1.10.445
2g1pSAHDNA adenine methylase2.1.1.720.445
2hw2RFPRifampin ADP-ribosyl transferase/0.445
2j9lATPH(+)/Cl(-) exchange transporter 5/0.445
2jih097A disintegrin and metalloproteinase with thrombospondin motifs 13.4.240.445
2v59LZKBiotin carboxylase6.3.4.140.445
2yltFADPhenylacetone monooxygenase1.14.13.920.445
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.445
3fyvXCFDihydrofolate reductase1.5.1.30.445
3lfeZ84Mitogen-activated protein kinase 14/0.445
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.445
3nxxNDPDihydrofolate reductase1.5.1.30.445
3oqfS51Renin3.4.23.150.445
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.445
3vhiVHIAvidin/0.445
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.445
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4bw39BMBromodomain-containing protein 4/0.445
4dc0NDPPutative ketoacyl reductase1.3.10.445
4iaq2GM5-hydroxytryptamine receptor 1B/0.445
4j0r1H2Bromodomain-containing protein 4/0.445
4kl9NDPDihydrofolate reductase1.5.1.30.445
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.445
4mv1ADPBiotin carboxylase6.3.4.140.445
4pd6URINucleoside permease/0.445
4ys22BAUncharacterized protein/0.445
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.445
1bq1CB3Thymidylate synthase/0.444
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.444
1nzq162Prothrombin3.4.21.50.444
1psa0ZLPepsin A3.4.23.10.444
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.444
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.444
1tkzH16Gag-Pol polyprotein2.7.7.490.444
1ypkCCRProthrombin3.4.21.50.444
1z7yAA5Cysteine synthase 12.5.1.470.444
2fziDH3Dihydrofolate reductase1.5.1.30.444
2hl1A3SThreonine--tRNA ligase6.1.1.30.444
2j2pSC2Ficolin-2/0.444
2q7gCCLPyrrolysine--tRNA ligase/0.444
2qg4NADUDP-glucose 6-dehydrogenase1.1.1.220.444
2v3oI26Prothrombin3.4.21.50.444
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2wi4ZZ4Heat shock protein HSP 90-alpha/0.444
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.444
2z2w770Wee1-like protein kinase2.7.10.20.444
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.444
3gtsD3MDdmC/0.444
3h2sNDPPutative NADH-flavin reductase/0.444
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.444
3iogSDFMetallo-beta-lactamase type 2/0.444
3ivcFG4Pantothenate synthetase6.3.2.10.444
3qeoLLTDeoxycytidine kinase2.7.1.740.444
3rmeRMEAcidic mammalian chitinase3.2.1.140.444
3sqyQ11Dihydrofolate reductase1.5.1.30.444
3to3ATPPetrobactin biosynthesis protein AsbB/0.444
3v1uHXC3-oxoacyl-(Acyl-carrier-protein) reductase/0.444
4aosFADSteroid monooxygenase/0.444
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.444
4b4vL34Bifunctional protein FolD/0.444
4jq3ZOMAldo-keto reductase family 1 member C2/0.444
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.444
4l8u9AZSerum albumin/0.444
4o7uTHFThymidylate synthase/0.444
4okx198Androgen receptor/0.444
4qa0SHHHistone deacetylase 83.5.1.980.444
5fd8A5APutative carboxypeptidase yocD/0.444
1cbsREACellular retinoic acid-binding protein 2/0.443
1e7aPFLSerum albumin/0.443
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.443
1h65GDPTranslocase of chloroplast 343.6.50.443
1hfqMOTDihydrofolate reductase1.5.1.30.443
1t7rDHTAndrogen receptor/0.443
1tl1H18Gag-Pol polyprotein2.7.7.490.443
2clfF6FTryptophan synthase alpha chain/0.443
2fai459Estrogen receptor/0.443
2p5yNADUDP-glucose 4-epimerase/0.443
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.443
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2vbdV10Isopenicillin N synthase1.21.3.10.443
2wecPP5Penicillopepsin-13.4.23.200.443
2x9vTMQPteridine reductase/0.443
2zjmF1MBeta-secretase 13.4.23.460.443
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3dux64UProthrombin3.4.21.50.443
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.443
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.443
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.443
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3pm9FADPutative oxidoreductase/0.443
3pqbVGPPutative oxidoreductase/0.443
3qm4PN0Cytochrome P450 2D6/0.443
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3vgwNVZAvidin/0.443
3vi7CBDHematopoietic prostaglandin D synthase/0.443
3vt65YIVitamin D3 receptor/0.443
3w0aDS5Vitamin D3 receptor/0.443
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.443
3zqtTESAndrogen receptor/0.443
3zvuA8SAbscisic acid receptor PYR1/0.443
4ap1FADSteroid monooxygenase/0.443
4cjp4D2Integrase/0.443
4dpeNGHStromelysin-13.4.24.170.443
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
4fxy0W2Neurolysin, mitochondrial3.4.24.160.443
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.443
4ixgIXGDihydrofolate reductase1.5.1.30.443
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.443
4x5gFOLDihydrofolate reductase1.5.1.30.443
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.443
5ikqJMSProstaglandin G/H synthase 21.14.99.10.443
1aiqCB3Thymidylate synthase/0.442
1eg2MTAModification methylase RsrI2.1.1.720.442
1fmlRTLRetinol dehydratase/0.442
1g28FMNPHY3/0.442
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
1ju6LYAThymidylate synthase2.1.1.450.442
1lluNADAlcohol dehydrogenase/0.442
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.442
1n71COAAac(6')-Ii protein/0.442
1p33MTXPteridine reductase 11.5.1.330.442
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1xq3R18Androgen receptor/0.442
1y6aAAZVascular endothelial growth factor receptor 22.7.10.10.442
2aa6STRMineralocorticoid receptor/0.442
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.442
2b9wFADPutative aminooxidase/0.442
2dxfGNPNucleoside diphosphate kinase2.7.4.60.442
2qhwPZZBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.442
2vjmCOAFormyl-CoA:oxalate CoA-transferase/0.442
2x7bCOAN-alpha-acetyltransferase2.3.10.442
2x7hPFNProstaglandin reductase 310.442
3bw2FMNPutative 2-nitropropane dioxygenase/0.442
3c3dFO12-phospho-L-lactate transferase/0.442
3crzFADFerredoxin--NADP+ reductase/0.442
3datMTXDihydrofolate reductase/0.442
3erdDESEstrogen receptor/0.442
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3qly55VUncharacterized protein/0.442
3rupADPBiotin carboxylase6.3.4.140.442
3ryrCMPcAMP-activated global transcriptional regulator CRP/0.442
3ug8IMNAldo-keto reductase family 1 member C3/0.442
3vt7VDXVitamin D3 receptor/0.442
3w0jT08Vitamin D3 receptor/0.442
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.442
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.442
4dfrMTXDihydrofolate reductase1.5.1.30.442
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.442
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.442
4hdrDMDArsB/0.442
4ienCOAPutative acyl-CoA hydrolase/0.442
4j7xSASSepiapterin reductase1.1.1.1530.442
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.442
4kwhNAPReductase homolog/0.442
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.442
4nb6444Nuclear receptor ROR-gamma/0.442
4ofrDHTAndrogen receptor/0.442
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.442
4xrgNADHomospermidine synthase2.5.1.440.442
4yl2FMNLactate oxidase/0.442
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.442
5e8xSTUTGF-beta receptor type-12.7.11.300.442
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.442
5k2cZMAAdenosine receptor A2a/0.442
1d8fSPIStromelysin-13.4.24.170.441
1dyrTOPDihydrofolate reductase1.5.1.30.441
1hf3NADAlcohol dehydrogenase E chain1.1.1.10.441
1ihiIU5Aldo-keto reductase family 1 member C2/0.441
1iwjCAMCamphor 5-monooxygenase1.14.15.10.441
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
1q1wFADPutidaredoxin reductase1.18.1.50.441
1s7gNADNAD-dependent protein deacylase 2/0.441
1u5cBIKL-lactate dehydrogenase1.1.1.270.441
1uy9PU6Heat shock protein HSP 90-alpha/0.441
1vruAAPGag-Pol polyprotein2.7.7.490.441
1vyrFMNPentaerythritol tetranitrate reductase/0.441
1x31FMNSubunit alpha of sarocosine oxidase/0.441
1x31FMNSubunit beta of sarcosine oxidase/0.441
1yw1FMNPutative monooxygenase MoxC1.140.441
2acwUPGGlycosyltransferase/0.441
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
2e95B75Geranylgeranyl pyrophosphate synthase/0.441
2ea4F79Methionine aminopeptidase 2/0.441
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.441
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.441
2o4jVD4Vitamin D3 receptor/0.441
2o7oDXTTetracycline repressor protein class D/0.441
2rg5279Mitogen-activated protein kinase 14/0.441
2trtTACTetracycline repressor protein class D/0.441
2v3hI25Prothrombin3.4.21.50.441
2yemWSHBromodomain-containing protein 4/0.441
2ym1FADPhenylacetone monooxygenase1.14.13.920.441
3a1l2CCCytochrome P450/0.441
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.441
3ft8MOJHeat shock protein HSP 90-alpha/0.441
3fywXCFDihydrofolate reductase1.5.1.30.441
3i8aN22Dihydrofolate reductase1.5.1.30.441
3mjeNDPAmphB/0.441
3mnpDEXGlucocorticoid receptor/0.441
3n0yAPCAdenylate cyclase 2/0.441
3n19FNRXenobiotic reductase/0.441
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.441
3oimVZ5Carbonic anhydrase 24.2.1.10.441
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.441
3rdoBTNStreptavidin/0.441
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3s41S41Glucokinase2.7.1.20.441
3sdkP3NProteasome subunit beta type-53.4.25.10.441
3sdkP3NProteasome subunit beta type-63.4.25.10.441
3uwqU5POrotidine 5'-phosphate decarboxylase/0.441
3vf80JETyrosine-protein kinase SYK2.7.10.20.441
3wfgWFGMineralocorticoid receptor/0.441
3zkuHCVIsopenicillin N synthase1.21.3.10.441
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.441
4abzT1CTetracycline repressor protein class D/0.441
4boeCLRJapanin/0.441
4ddrMMVDihydrofolate reductase1.5.1.30.441
4dymIYZActivin receptor type-12.7.11.300.441
4ly91YYGlucokinase regulatory protein/0.441
4zm6ACON-acetyl-beta-D glucosaminidase/0.441
5cvhADPCasein kinase II subunit alpha2.7.11.10.441
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.441
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.441
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.441
1c4uIH1Prothrombin3.4.21.50.440
1dr2TAPDihydrofolate reductase1.5.1.30.440
1ie8KH1Vitamin D3 receptor/0.440
1kl2FONSerine hydroxymethyltransferase/0.440
1kmvLIIDihydrofolate reductase1.5.1.30.440
1m7aMQUDihydrofolate reductase1.5.1.30.440
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.440
1mvsDTMDihydrofolate reductase1.5.1.30.440
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.440
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1t4v14AProthrombin3.4.21.50.440
1xdkREARetinoic acid receptor beta/0.440
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
1zrb062Prothrombin3.4.21.50.440
2a3iC0RMineralocorticoid receptor/0.440
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.440
2qhxFE1Pteridine reductase 11.5.1.330.440
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.440
2xejOKDGlutamate carboxypeptidase 23.4.17.210.440
3cr0809Wee1-like protein kinase2.7.10.20.440
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3gxlQIGTGF-beta receptor type-12.7.11.300.440
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.440
3lanKBTGag-Pol polyprotein2.7.7.490.440
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3och2MXDihydrofolate reductase1.5.1.30.440
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.440
3rl45GPMetallophosphoesterase MPPED23.10.440
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.440
3v49PK0Androgen receptor/0.440
3wnzADPAlanine--anticapsin ligase/0.440
4at0FADPossible succinate dehydrogenase/0.440
4dz7D02Carbonic anhydrase 24.2.1.10.440
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
4gk3L87Ephrin type-A receptor 32.7.10.10.440
4h9506UDihydrofolate reductase1.5.1.30.440
4iteTEYVitamin D3 receptor/0.440
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.440
4k7yFMNNADPH dehydrogenase 11.6.99.10.440
4kfbT27Gag-Pol polyprotein2.7.7.490.440
4q15HFGProline--tRNA ligase6.1.1.150.440
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.440
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.440
4uugPXGBranched-chain amino acid aminotransferase, putative/0.440
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.440
5iqgGDPBifunctional AAC/APH2.3.10.440
4ug2NGIAdenosine receptor A2a/0.440