sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2rh9	IGP	Tryptophan synthase alpha chain

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2rh9	IGP	Tryptophan synthase alpha chain	/	1.000
1k8y	13P	Tryptophan synthase alpha chain	/	0.726
1beu	IPL	Tryptophan synthase alpha chain	/	0.716
1kfb	IGP	Tryptophan synthase alpha chain	/	0.687
2rhg	IGP	Tryptophan synthase alpha chain	/	0.667
1k7f	IAV	Tryptophan synthase alpha chain	/	0.650
1kfc	IPL	Tryptophan synthase alpha chain	/	0.635
1qoq	IGP	Tryptophan synthase alpha chain	/	0.597
4y6g	F6F	Tryptophan synthase alpha chain	/	0.531
1a5b	IGP	Tryptophan synthase alpha chain	/	0.503
2clf	F6F	Tryptophan synthase alpha chain	/	0.488
4zqc	F6F	Tryptophan synthase alpha chain	/	0.488
2cle	F6F	Tryptophan synthase alpha chain	/	0.471
1k8z	IAG	Tryptophan synthase alpha chain	/	0.457