sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rg6 | 287 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.619 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.605 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.604 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.601 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.601 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.593 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.590 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.588 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.586 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.586 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.578 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.571 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.569 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.569 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.568 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.561 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.559 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.556 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.554 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.550 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.550 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.547 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.545 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.542 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.535 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.531 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.526 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.524 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.506 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.504 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.504 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.501 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.501 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.495 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.494 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.492 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.491 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.491 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.487 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.484 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.484 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.482 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.481 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.479 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.478 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.478 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.477 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.477 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.476 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.476 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.476 | |
| 4pd6 | URI | Nucleoside permease | / | 0.476 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.475 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.475 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.475 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.475 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.474 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.473 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.473 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.472 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.472 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.472 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 3lfa | 1N1 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.471 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.470 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.470 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.470 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.470 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.470 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.470 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.470 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.469 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.469 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.469 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.469 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.469 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.469 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.469 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.468 | |
| 1qvn | FRI | Interleukin-2 | / | 0.468 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.468 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.468 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 2iml | FMN | Uncharacterized protein | / | 0.467 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.467 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.467 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.467 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.466 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.466 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.466 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.465 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.465 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.465 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.465 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.464 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.464 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.464 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.464 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.464 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.464 | |
| 5a3b | APR | SIR2 family protein | / | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.463 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2gek | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.463 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.463 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.463 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.463 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.463 | |
| 1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.462 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.462 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.461 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.461 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.461 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.461 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.461 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.461 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.460 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.460 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.460 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.460 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.460 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.460 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.460 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.460 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.460 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.460 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.459 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.459 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.459 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1gqt | ACP | Ribokinase | / | 0.458 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.458 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 2y3r | TRK | TamL | / | 0.458 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.458 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.458 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.458 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.458 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.457 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.457 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.457 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.457 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.457 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.457 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.457 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.457 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.457 | |
| 1c70 | L75 | Protease | / | 0.456 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1hzz | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.456 | |
| 1wkg | POI | [LysW]-aminoadipate semialdehyde transaminase | / | 0.456 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.456 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.456 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.456 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.456 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.456 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.456 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.456 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.455 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.455 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.455 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.455 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3zt0 | ZT0 | Integrase | / | 0.455 | |
| 3zuy | TCH | Transporter | / | 0.455 | |
| 4eh3 | NAR | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.455 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.455 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.454 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.454 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.454 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.454 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.454 | |
| 3cvu | FAD | RE11660p | / | 0.454 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.454 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.454 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.454 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.454 | |
| 3w0q | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.454 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.454 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.453 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.453 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.453 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.453 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.453 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.453 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.453 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.453 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.452 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.452 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.452 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.452 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.452 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.452 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4r9u | ANP | Vitamin B12 import ATP-binding protein BtuD | / | 0.452 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.451 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.451 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.451 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.451 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 4cec | 2SS | Integrase | / | 0.451 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.451 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.451 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.451 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4lb2 | DM5 | Serum albumin | / | 0.451 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.450 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.450 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.450 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.450 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.450 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.450 | |
| 3wec | AUI | Cytochrome P450 | / | 0.450 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.450 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.450 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 1eio | GCH | Gastrotropin | / | 0.449 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 1ie4 | T44 | Transthyretin | / | 0.449 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.449 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.449 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.449 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.449 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.449 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.449 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.449 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.449 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.449 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.449 | |
| 3lu8 | IQX | Serum albumin | / | 0.449 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.449 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.449 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.449 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.449 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.449 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.449 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.448 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.448 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2b8t | THM | Thymidine kinase | / | 0.448 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.448 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.448 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.448 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.448 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.448 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.448 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.448 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4l4x | NDP | AmphI | / | 0.448 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.448 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.448 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.448 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.447 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.447 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.447 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.447 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.447 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.447 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.447 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.447 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.447 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.447 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.447 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.446 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.446 | |
| 1osv | CHC | Bile acid receptor | / | 0.446 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.446 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2bxm | IMN | Serum albumin | / | 0.446 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2i4u | DJR | Protease | / | 0.446 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.446 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.446 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.446 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.446 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.446 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.446 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.446 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 1iy8 | NAD | Levodione reductase | / | 0.445 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.445 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.445 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.445 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.445 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.445 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3dtw | A96 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.445 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.445 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.445 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.445 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.445 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.444 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.444 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.444 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.444 | |
| 3b2e | ADP | ATPase GET3 | / | 0.444 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.444 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.444 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.444 | |
| 4yqf | GDP | Septin-9 | / | 0.444 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.444 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.443 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.443 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.443 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2i0d | MUT | Protease | / | 0.443 | |
| 2nr4 | FMN | Conserved protein | / | 0.443 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.443 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.443 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 3zux | TCH | Transporter | / | 0.443 | |
| 4anb | YQY | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.443 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.443 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1lde | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.442 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.442 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.441 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.441 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.441 | |
| 1ztf | XYA | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.441 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.441 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.441 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.441 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.441 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.441 | |
| 4cf8 | V7H | Integrase | / | 0.441 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.441 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.441 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.441 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.441 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.440 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.440 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.440 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 2cvw | GDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.440 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2wq6 | FAD | RE11660p | / | 0.440 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.440 | |
| 3ieu | GDP | GTPase Era | / | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.440 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
| 5a3c | NAD | SIR2 family protein | / | 0.440 |