sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rew | REW | Peroxisome proliferator-activated receptor alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 1.000 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.537 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.534 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.508 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.498 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.494 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.493 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 3lu8 | IQX | Serum albumin | / | 0.447 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.440 |