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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r3kSCQCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r3kSCQCyclin-dependent kinase 22.7.11.221.000
2r3jSCJCyclin-dependent kinase 22.7.11.220.665
3iggEFQCyclin-dependent kinase 22.7.11.220.628
3qtrX36Cyclin-dependent kinase 22.7.11.220.594
2r3lSCWCyclin-dependent kinase 22.7.11.220.590
3lfnA27Cyclin-dependent kinase 22.7.11.220.582
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.577
3rjc06ZCyclin-dependent kinase 22.7.11.220.571
4ek816KCyclin-dependent kinase 22.7.11.220.569
3rk708ZCyclin-dependent kinase 22.7.11.220.557
2r3p3SCCyclin-dependent kinase 22.7.11.220.552
4acm7YGCyclin-dependent kinase 22.7.11.220.552
2r3mSCXCyclin-dependent kinase 22.7.11.220.551
3s1h56ZCyclin-dependent kinase 22.7.11.220.551
4fkt48KCyclin-dependent kinase 22.7.11.220.550
1g5sI17Cyclin-dependent kinase 22.7.11.220.549
3ig7EFPCyclin-dependent kinase 22.7.11.220.549
2a0cCK9Cyclin-dependent kinase 22.7.11.220.546
3rak03ZCyclin-dependent kinase 22.7.11.220.546
3r9dX6BCyclin-dependent kinase 22.7.11.220.545
1oitHDTCyclin-dependent kinase 22.7.11.220.543
3qtxX43Cyclin-dependent kinase 22.7.11.220.540
4fks46KCyclin-dependent kinase 22.7.11.220.540
4fkv61KCyclin-dependent kinase 22.7.11.220.539
3pj8404Cyclin-dependent kinase 22.7.11.220.537
2btrU73Cyclin-dependent kinase 22.7.11.220.536
3qzgX67Cyclin-dependent kinase 22.7.11.220.536
2w1hL0FCyclin-dependent kinase 22.7.11.220.534
1pxlCK4Cyclin-dependent kinase 22.7.11.220.533
1w0xOLOCyclin-dependent kinase 22.7.11.220.533
1y91CT9Cyclin-dependent kinase 22.7.11.220.531
1pxoCK7Cyclin-dependent kinase 22.7.11.220.529
2xmyCDKCyclin-dependent kinase 22.7.11.220.526
3lfqA28Cyclin-dependent kinase 22.7.11.220.525
3r83Z14Cyclin-dependent kinase 22.7.11.220.525
2vv9IM9Cyclin-dependent kinase 22.7.11.220.523
3rpv26ZCyclin-dependent kinase 22.7.11.220.522
3r7yZ04Cyclin-dependent kinase 22.7.11.220.520
2b52D42Cyclin-dependent kinase 22.7.11.220.518
3rahO1ZCyclin-dependent kinase 22.7.11.220.518
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.517
4fkj11KCyclin-dependent kinase 22.7.11.220.517
3qwjX6ACyclin-dependent kinase 22.7.11.220.516
4bgh3I6Cyclin-dependent kinase 22.7.11.220.515
2w06FRVCyclin-dependent kinase 22.7.11.220.513
2w17I19Cyclin-dependent kinase 22.7.11.220.513
3rni21ZCyclin-dependent kinase 22.7.11.220.513
2r3fSC8Cyclin-dependent kinase 22.7.11.220.512
3r8lZ30Cyclin-dependent kinase 22.7.11.220.512
4fkpLS5Cyclin-dependent kinase 22.7.11.220.512
1p2a5BNCyclin-dependent kinase 22.7.11.220.511
3r1yX76Cyclin-dependent kinase 22.7.11.220.511
3qqhX0ACyclin-dependent kinase 22.7.11.220.509
4fkq42KCyclin-dependent kinase 22.7.11.220.509
2c6o4SPCyclin-dependent kinase 22.7.11.220.508
2vthLZ2Cyclin-dependent kinase 22.7.11.220.508
3wblPDYCyclin-dependent kinase 22.7.11.220.506
3sw418KCyclin-dependent kinase 22.7.11.220.504
3ezvEZVCyclin-dependent kinase 22.7.11.220.502
3qxpX64Cyclin-dependent kinase 22.7.11.220.502
3lfsA07Cyclin-dependent kinase 22.7.11.220.501
3r8pZ46Cyclin-dependent kinase 22.7.11.220.501
2c6iDT1Cyclin-dependent kinase 22.7.11.220.500
3rk909ZCyclin-dependent kinase 22.7.11.220.500
4fki09KCyclin-dependent kinase 22.7.11.220.500
3ral04ZCyclin-dependent kinase 22.7.11.220.499
4fkg4CKCyclin-dependent kinase 22.7.11.220.497
1pxmCK5Cyclin-dependent kinase 22.7.11.220.496
3fz1B98Cyclin-dependent kinase 22.7.11.220.496
3rm618ZCyclin-dependent kinase 22.7.11.220.494
4fkr45KCyclin-dependent kinase 22.7.11.220.493
2uznC96Cyclin-dependent kinase 22.7.11.220.489
3qu0X40Cyclin-dependent kinase 22.7.11.220.489
1gii1PUCyclin-dependent kinase 22.7.11.220.488
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.488
2vttLZDCyclin-dependent kinase 22.7.11.220.488
3qxoX65Cyclin-dependent kinase 22.7.11.220.487
2a4lRRCCyclin-dependent kinase 22.7.11.220.485
2b53D23Cyclin-dependent kinase 22.7.11.220.485
2uzoC62Cyclin-dependent kinase 22.7.11.220.484
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.484
3qtuX44Cyclin-dependent kinase 22.7.11.220.483
1gih1PUCyclin-dependent kinase 22.7.11.220.482
3qqlX03Cyclin-dependent kinase 22.7.11.220.482
3r71X86Cyclin-dependent kinase 22.7.11.220.482
3s2pPMUCyclin-dependent kinase 22.7.11.220.482
3rmf20ZCyclin-dependent kinase 22.7.11.220.481
3rkb12ZCyclin-dependent kinase 22.7.11.220.480
2r3gSC9Cyclin-dependent kinase 22.7.11.220.479
3rpo24ZCyclin-dependent kinase 22.7.11.220.478
3r7uX96Cyclin-dependent kinase 22.7.11.220.477
3r8vZ62Cyclin-dependent kinase 22.7.11.220.476
4nj32KDCyclin-dependent kinase 22.7.11.220.476
1b38ATPCyclin-dependent kinase 22.7.11.220.475
1ke5LS1Cyclin-dependent kinase 22.7.11.220.475
2vtsLZCCyclin-dependent kinase 22.7.11.220.475
1v1k3FPCyclin-dependent kinase 22.7.11.220.474
2r3q5SCCyclin-dependent kinase 22.7.11.220.474
3rm719ZCyclin-dependent kinase 22.7.11.220.474
3sqq99ZCyclin-dependent kinase 22.7.11.220.474
2exmZIPCyclin-dependent kinase 22.7.11.220.473
1b39ATPCyclin-dependent kinase 22.7.11.220.472
3ezrEZRCyclin-dependent kinase 22.7.11.220.471
2r3o2SCCyclin-dependent kinase 22.7.11.220.469
1ckpPVBCyclin-dependent kinase 22.7.11.220.467
1fvt106Cyclin-dependent kinase 22.7.11.220.466
1w8cN69Cyclin-dependent kinase 22.7.11.220.464
4ii5ADPCyclin-dependent kinase 22.7.11.220.464
4fklCK2Cyclin-dependent kinase 22.7.11.220.462
3qqkX02Cyclin-dependent kinase 22.7.11.220.461
2r3r6SCCyclin-dependent kinase 22.7.11.220.459
3qruX19Cyclin-dependent kinase 22.7.11.220.459
3r7vZ02Cyclin-dependent kinase 22.7.11.220.459
4fx360KCyclin-dependent kinase 22.7.11.220.459
1urwI1PCyclin-dependent kinase 22.7.11.220.458
2btsU32Cyclin-dependent kinase 22.7.11.220.458
4lyn1YGCyclin-dependent kinase 22.7.11.220.458
1ykr628Cyclin-dependent kinase 22.7.11.220.457
3rk507ZCyclin-dependent kinase 22.7.11.220.457
2c6kDT2Cyclin-dependent kinase 22.7.11.220.456
1fvv107Cyclin-dependent kinase 22.7.11.220.455
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.455
4kd11QKCyclin-dependent kinase 22.7.11.220.455
3qtwX3ACyclin-dependent kinase 22.7.11.220.454
3r6xX84Cyclin-dependent kinase 22.7.11.220.453
1vyw292Cyclin-dependent kinase 22.7.11.220.450
1dm2HMDCyclin-dependent kinase 22.7.11.220.449
1pxpCK8Cyclin-dependent kinase 22.7.11.220.449
3qx2X63Cyclin-dependent kinase 22.7.11.220.449
3r9hZ67Cyclin-dependent kinase 22.7.11.220.449
2b55D31Cyclin-dependent kinase 22.7.11.220.448
3qtzX42Cyclin-dependent kinase 22.7.11.220.448
1ke7LS3Cyclin-dependent kinase 22.7.11.220.447
2c69CT8Cyclin-dependent kinase 22.7.11.220.447
2r3iSCFCyclin-dependent kinase 22.7.11.220.447
3pxyJWSCyclin-dependent kinase 22.7.11.220.447
1oirHDYCyclin-dependent kinase 22.7.11.220.446
3ti1B49Cyclin-dependent kinase 22.7.11.220.446
4fko20KCyclin-dependent kinase 22.7.11.220.446
1oiqHDUCyclin-dependent kinase 22.7.11.220.445
1e1xNW1Cyclin-dependent kinase 22.7.11.220.444
1ke9LS5Cyclin-dependent kinase 22.7.11.220.442
3r73X87Cyclin-dependent kinase 22.7.11.220.442
3unk0BYCyclin-dependent kinase 22.7.11.220.442
1hckATPCyclin-dependent kinase 22.7.11.220.441
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
1pyePM1Cyclin-dependent kinase 22.7.11.220.441
1y8yCT7Cyclin-dependent kinase 22.7.11.220.441
3roy22ZCyclin-dependent kinase 22.7.11.220.441
3rpy27ZCyclin-dependent kinase 22.7.11.220.441
3s0o50ZCyclin-dependent kinase 22.7.11.220.441
4eon1ROCyclin-dependent kinase 22.7.11.220.441
2c6lDT4Cyclin-dependent kinase 22.7.11.220.440
2wpa889Cyclin-dependent kinase 22.7.11.220.440
3tiz3TICyclin-dependent kinase 22.7.11.220.440
4fkw62KCyclin-dependent kinase 22.7.11.220.440