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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r3jSCJCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r3jSCJCyclin-dependent kinase 22.7.11.221.000
4fkt48KCyclin-dependent kinase 22.7.11.220.581
3lfnA27Cyclin-dependent kinase 22.7.11.220.559
4ek816KCyclin-dependent kinase 22.7.11.220.542
2r3kSCQCyclin-dependent kinase 22.7.11.220.535
3lfqA28Cyclin-dependent kinase 22.7.11.220.522
2btrU73Cyclin-dependent kinase 22.7.11.220.513
4fklCK2Cyclin-dependent kinase 22.7.11.220.512
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.510
2w17I19Cyclin-dependent kinase 22.7.11.220.508
1oirHDYCyclin-dependent kinase 22.7.11.220.506
4fks46KCyclin-dependent kinase 22.7.11.220.499
1pxmCK5Cyclin-dependent kinase 22.7.11.220.496
2c6o4SPCyclin-dependent kinase 22.7.11.220.494
1oitHDTCyclin-dependent kinase 22.7.11.220.491
2xmyCDKCyclin-dependent kinase 22.7.11.220.489
3ezvEZVCyclin-dependent kinase 22.7.11.220.489
1y91CT9Cyclin-dependent kinase 22.7.11.220.488
3iggEFQCyclin-dependent kinase 22.7.11.220.487
3r1yX76Cyclin-dependent kinase 22.7.11.220.487
3r83Z14Cyclin-dependent kinase 22.7.11.220.487
2a0cCK9Cyclin-dependent kinase 22.7.11.220.486
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.485
3r8lZ30Cyclin-dependent kinase 22.7.11.220.485
1w8cN69Cyclin-dependent kinase 22.7.11.220.483
1ykr628Cyclin-dependent kinase 22.7.11.220.483
2vv9IM9Cyclin-dependent kinase 22.7.11.220.478
2c6lDT4Cyclin-dependent kinase 22.7.11.220.476
2r3mSCXCyclin-dependent kinase 22.7.11.220.476
2r3p3SCCyclin-dependent kinase 22.7.11.220.474
3fz1B98Cyclin-dependent kinase 22.7.11.220.474
4fkg4CKCyclin-dependent kinase 22.7.11.220.474
4fki09KCyclin-dependent kinase 22.7.11.220.474
2w05FRTCyclin-dependent kinase 22.7.11.220.471
1gii1PUCyclin-dependent kinase 22.7.11.220.470
2r3lSCWCyclin-dependent kinase 22.7.11.220.467
4fkv61KCyclin-dependent kinase 22.7.11.220.467
1pxlCK4Cyclin-dependent kinase 22.7.11.220.465
3s1h56ZCyclin-dependent kinase 22.7.11.220.464
1pxoCK7Cyclin-dependent kinase 22.7.11.220.463
3r8vZ62Cyclin-dependent kinase 22.7.11.220.460
3qzgX67Cyclin-dependent kinase 22.7.11.220.459
4fkq42KCyclin-dependent kinase 22.7.11.220.458
2vthLZ2Cyclin-dependent kinase 22.7.11.220.453
2r3q5SCCyclin-dependent kinase 22.7.11.220.452
2b53D23Cyclin-dependent kinase 22.7.11.220.451
3r7yZ04Cyclin-dependent kinase 22.7.11.220.451
2r3iSCFCyclin-dependent kinase 22.7.11.220.450
1b38ATPCyclin-dependent kinase 22.7.11.220.449
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.448
4ek610KCyclin-dependent kinase 22.7.11.220.448
3rahO1ZCyclin-dependent kinase 22.7.11.220.444
2b52D42Cyclin-dependent kinase 22.7.11.220.440