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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r3gSC9Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r3gSC9Cyclin-dependent kinase 22.7.11.221.000
2r3fSC8Cyclin-dependent kinase 22.7.11.220.633
2r3iSCFCyclin-dependent kinase 22.7.11.220.616
2r3r6SCCyclin-dependent kinase 22.7.11.220.600
4fkj11KCyclin-dependent kinase 22.7.11.220.596
4fkg4CKCyclin-dependent kinase 22.7.11.220.588
1w8cN69Cyclin-dependent kinase 22.7.11.220.587
1h0vUN4Cyclin-dependent kinase 22.7.11.220.586
4fkt48KCyclin-dependent kinase 22.7.11.220.578
3qx2X63Cyclin-dependent kinase 22.7.11.220.564
3rahO1ZCyclin-dependent kinase 22.7.11.220.563
4fklCK2Cyclin-dependent kinase 22.7.11.220.562
2btrU73Cyclin-dependent kinase 22.7.11.220.561
1b39ATPCyclin-dependent kinase 22.7.11.220.557
2j9mPY8Cyclin-dependent kinase 22.7.11.220.557
1b38ATPCyclin-dependent kinase 22.7.11.220.556
1vyzN5BCyclin-dependent kinase 22.7.11.220.556
2c6mDT5Cyclin-dependent kinase 22.7.11.220.554
2r3o2SCCyclin-dependent kinase 22.7.11.220.550
1h0w207Cyclin-dependent kinase 22.7.11.220.548
3r7yZ04Cyclin-dependent kinase 22.7.11.220.547
2a4lRRCCyclin-dependent kinase 22.7.11.220.543
2c69CT8Cyclin-dependent kinase 22.7.11.220.543
2c6iDT1Cyclin-dependent kinase 22.7.11.220.543
3r83Z14Cyclin-dependent kinase 22.7.11.220.541
4fkr45KCyclin-dependent kinase 22.7.11.220.536
4fkpLS5Cyclin-dependent kinase 22.7.11.220.534
3r1yX76Cyclin-dependent kinase 22.7.11.220.533
3qqhX0ACyclin-dependent kinase 22.7.11.220.532
3raiX85Cyclin-dependent kinase 22.7.11.220.532
2vtsLZCCyclin-dependent kinase 22.7.11.220.528
3qzgX67Cyclin-dependent kinase 22.7.11.220.528
2r3p3SCCyclin-dependent kinase 22.7.11.220.527
3lfnA27Cyclin-dependent kinase 22.7.11.220.526
3rm719ZCyclin-dependent kinase 22.7.11.220.524
1ckpPVBCyclin-dependent kinase 22.7.11.220.522
2b54D05Cyclin-dependent kinase 22.7.11.220.521
2exmZIPCyclin-dependent kinase 22.7.11.220.521
3qziX72Cyclin-dependent kinase 22.7.11.220.519
1w0xOLOCyclin-dependent kinase 22.7.11.220.518
3r8uZ31Cyclin-dependent kinase 22.7.11.220.518
3qqlX03Cyclin-dependent kinase 22.7.11.220.517
4fki09KCyclin-dependent kinase 22.7.11.220.517
3lfqA28Cyclin-dependent kinase 22.7.11.220.516
3fz1B98Cyclin-dependent kinase 22.7.11.220.515
3qwjX6ACyclin-dependent kinase 22.7.11.220.515
3r28XA0Cyclin-dependent kinase 22.7.11.220.515
2r3kSCQCyclin-dependent kinase 22.7.11.220.514
2r3lSCWCyclin-dependent kinase 22.7.11.220.514
2uznC96Cyclin-dependent kinase 22.7.11.220.514
3rm618ZCyclin-dependent kinase 22.7.11.220.514
3rpo24ZCyclin-dependent kinase 22.7.11.220.514
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.513
2r3q5SCCyclin-dependent kinase 22.7.11.220.512
2w05FRTCyclin-dependent kinase 22.7.11.220.512
2btsU32Cyclin-dependent kinase 22.7.11.220.511
3roy22ZCyclin-dependent kinase 22.7.11.220.510
4ek816KCyclin-dependent kinase 22.7.11.220.509
4fkq42KCyclin-dependent kinase 22.7.11.220.509
2r64740Cyclin-dependent kinase 22.7.11.220.508
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.508
3iggEFQCyclin-dependent kinase 22.7.11.220.507
2a0cCK9Cyclin-dependent kinase 22.7.11.220.506
2c6o4SPCyclin-dependent kinase 22.7.11.220.506
3s2pPMUCyclin-dependent kinase 22.7.11.220.506
4nj32KDCyclin-dependent kinase 22.7.11.220.506
1e1xNW1Cyclin-dependent kinase 22.7.11.220.503
2c68CT6Cyclin-dependent kinase 22.7.11.220.503
2iw84SPCyclin-dependent kinase 22.7.11.220.502
4ez30S0Cyclin-dependent kinase 22.7.11.220.502
1oitHDTCyclin-dependent kinase 22.7.11.220.501
3qtzX42Cyclin-dependent kinase 22.7.11.220.500
3qzhX69Cyclin-dependent kinase 22.7.11.220.500
3r1sX73Cyclin-dependent kinase 22.7.11.220.500
3r9hZ67Cyclin-dependent kinase 22.7.11.220.499
3r7vZ02Cyclin-dependent kinase 22.7.11.220.498
1h1r6CPCyclin-dependent kinase 22.7.11.220.497
3rak03ZCyclin-dependent kinase 22.7.11.220.497
3s1h56ZCyclin-dependent kinase 22.7.11.220.496
1e1vCMGCyclin-dependent kinase 22.7.11.220.495
3ddqRRCCyclin-dependent kinase 22.7.11.220.495
3qu0X40Cyclin-dependent kinase 22.7.11.220.495
1ke5LS1Cyclin-dependent kinase 22.7.11.220.494
4ek610KCyclin-dependent kinase 22.7.11.220.494
1pxoCK7Cyclin-dependent kinase 22.7.11.220.493
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.492
3qtuX44Cyclin-dependent kinase 22.7.11.220.492
3qtxX43Cyclin-dependent kinase 22.7.11.220.492
3sqq99ZCyclin-dependent kinase 22.7.11.220.492
1ke7LS3Cyclin-dependent kinase 22.7.11.220.491
3rk708ZCyclin-dependent kinase 22.7.11.220.491
2c6kDT2Cyclin-dependent kinase 22.7.11.220.490
3qxoX65Cyclin-dependent kinase 22.7.11.220.489
3r6xX84Cyclin-dependent kinase 22.7.11.220.489
5aniES4Cyclin-dependent kinase 22.7.11.220.489
3r7uX96Cyclin-dependent kinase 22.7.11.220.488
3r73X87Cyclin-dependent kinase 22.7.11.220.487
3rpr25ZCyclin-dependent kinase 22.7.11.220.487
1pxmCK5Cyclin-dependent kinase 22.7.11.220.486
2b52D42Cyclin-dependent kinase 22.7.11.220.486
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.485
2w06FRVCyclin-dependent kinase 22.7.11.220.485
3pj8404Cyclin-dependent kinase 22.7.11.220.485
3r7iX9ICyclin-dependent kinase 22.7.11.220.485
4bcpT3CCyclin-dependent kinase 22.7.11.220.485
1ke8LS4Cyclin-dependent kinase 22.7.11.220.484
3ig7EFPCyclin-dependent kinase 22.7.11.220.483
4bgh3I6Cyclin-dependent kinase 22.7.11.220.482
1ke9LS5Cyclin-dependent kinase 22.7.11.220.481
1pxlCK4Cyclin-dependent kinase 22.7.11.220.481
2uzoC62Cyclin-dependent kinase 22.7.11.220.481
1y8yCT7Cyclin-dependent kinase 22.7.11.220.480
3r8lZ30Cyclin-dependent kinase 22.7.11.220.480
3rjc06ZCyclin-dependent kinase 22.7.11.220.480
1di8DTQCyclin-dependent kinase 22.7.11.220.479
3r9dX6BCyclin-dependent kinase 22.7.11.220.479
4kd11QKCyclin-dependent kinase 22.7.11.220.479
1h1s4SPCyclin-dependent kinase 22.7.11.220.478
1oguST8Cyclin-dependent kinase 22.7.11.220.478
1oiqHDUCyclin-dependent kinase 22.7.11.220.478
1ykr628Cyclin-dependent kinase 22.7.11.220.478
1gz8MBPCyclin-dependent kinase 22.7.11.220.477
2r3jSCJCyclin-dependent kinase 22.7.11.220.477
3qqfX07Cyclin-dependent kinase 22.7.11.220.476
4acm7YGCyclin-dependent kinase 22.7.11.220.476
3rk909ZCyclin-dependent kinase 22.7.11.220.475
3lfsA07Cyclin-dependent kinase 22.7.11.220.474
3qtrX36Cyclin-dependent kinase 22.7.11.220.474
4eon1ROCyclin-dependent kinase 22.7.11.220.473
1ke6LS2Cyclin-dependent kinase 22.7.11.220.472
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.472
3ezvEZVCyclin-dependent kinase 22.7.11.220.472
3r9nZ68Cyclin-dependent kinase 22.7.11.220.472
3rk507ZCyclin-dependent kinase 22.7.11.220.472
3rni21ZCyclin-dependent kinase 22.7.11.220.472
3ti1B49Cyclin-dependent kinase 22.7.11.220.472
1v1k3FPCyclin-dependent kinase 22.7.11.220.471
3qruX19Cyclin-dependent kinase 22.7.11.220.471
1pyePM1Cyclin-dependent kinase 22.7.11.220.470
2c4g514Cyclin-dependent kinase 22.7.11.220.470
2r3mSCXCyclin-dependent kinase 22.7.11.220.470
4fko20KCyclin-dependent kinase 22.7.11.220.470
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.468
2w17I19Cyclin-dependent kinase 22.7.11.220.468
3qwkX62Cyclin-dependent kinase 22.7.11.220.468
4bcnT9NCyclin-dependent kinase 22.7.11.220.468
1oiuN76Cyclin-dependent kinase 22.7.11.220.467
1oiyN41Cyclin-dependent kinase 22.7.11.220.467
1pxkCK3Cyclin-dependent kinase 22.7.11.220.467
2b55D31Cyclin-dependent kinase 22.7.11.220.467
3qqkX02Cyclin-dependent kinase 22.7.11.220.467
4ii5ADPCyclin-dependent kinase 22.7.11.220.466
4k8aK8AFocal adhesion kinase 12.7.10.20.466
1oi9N20Cyclin-dependent kinase 22.7.11.220.465
2vthLZ2Cyclin-dependent kinase 22.7.11.220.465
1y91CT9Cyclin-dependent kinase 22.7.11.220.464
1g5sI17Cyclin-dependent kinase 22.7.11.220.463
1h1q2A6Cyclin-dependent kinase 22.7.11.220.463
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.463
2vttLZDCyclin-dependent kinase 22.7.11.220.461
3r1qX75Cyclin-dependent kinase 22.7.11.220.461
3unj0BXCyclin-dependent kinase 22.7.11.220.461
4fkw62KCyclin-dependent kinase 22.7.11.220.461
1vyw292Cyclin-dependent kinase 22.7.11.220.460
2iw94SPCyclin-dependent kinase 22.7.11.220.460
3ral04ZCyclin-dependent kinase 22.7.11.220.459
3rkb12ZCyclin-dependent kinase 22.7.11.220.459
3pxyJWSCyclin-dependent kinase 22.7.11.220.458
1gij2PUCyclin-dependent kinase 22.7.11.220.457
1urwI1PCyclin-dependent kinase 22.7.11.220.457
4lyn1YGCyclin-dependent kinase 22.7.11.220.457
3ql8X01Cyclin-dependent kinase 22.7.11.220.456
2vv9IM9Cyclin-dependent kinase 22.7.11.220.455
4eor4SPCyclin-dependent kinase 22.7.11.220.455
3ddpRC8Cyclin-dependent kinase 22.7.11.220.454
3s0o50ZCyclin-dependent kinase 22.7.11.220.454
4eok4SPCyclin-dependent kinase 22.7.11.220.454
4eomATPCyclin-dependent kinase 22.7.11.220.454
1gih1PUCyclin-dependent kinase 22.7.11.220.453
3unk0BYCyclin-dependent kinase 22.7.11.220.453
4eos1ROCyclin-dependent kinase 22.7.11.220.453
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
1p2a5BNCyclin-dependent kinase 22.7.11.220.451
3bhtMFRCyclin-dependent kinase 22.7.11.220.451
1gii1PUCyclin-dependent kinase 22.7.11.220.449
1oirHDYCyclin-dependent kinase 22.7.11.220.449
3ezrEZRCyclin-dependent kinase 22.7.11.220.449
3py0SU9Cyclin-dependent kinase 22.7.11.220.449
1dm2HMDCyclin-dependent kinase 22.7.11.220.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.448
3r8pZ46Cyclin-dependent kinase 22.7.11.220.448
4fks46KCyclin-dependent kinase 22.7.11.220.448
3wblPDYCyclin-dependent kinase 22.7.11.220.447
1h1pCMGCyclin-dependent kinase 22.7.11.220.446
3qtqX35Cyclin-dependent kinase 22.7.11.220.446
1hckATPCyclin-dependent kinase 22.7.11.220.445
3my5RFZCyclin-dependent kinase 22.7.11.220.445
3sw418KCyclin-dependent kinase 22.7.11.220.445
4bcoT6QCyclin-dependent kinase 22.7.11.220.444
2duv371Cyclin-dependent kinase 22.7.11.220.443
2wpa889Cyclin-dependent kinase 22.7.11.220.443
3s00Z60Cyclin-dependent kinase 22.7.11.220.443
4fkv61KCyclin-dependent kinase 22.7.11.220.443
4fx360KCyclin-dependent kinase 22.7.11.220.443
4jajXU1Aurora kinase A2.7.11.10.442
1e9hINRCyclin-dependent kinase 22.7.11.220.441
1unlRRCCyclin-dependent-like kinase 52.7.11.10.440
2xmyCDKCyclin-dependent kinase 22.7.11.220.440
4bcmT7ZCyclin-dependent kinase 22.7.11.220.440