sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qxw | LDT | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.814 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.807 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.777 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.752 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.751 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.739 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.729 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.728 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.712 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.711 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.705 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.703 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.687 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.680 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.679 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.663 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.653 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.653 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.650 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.644 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.644 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.636 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.634 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.624 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.621 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.614 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.606 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.604 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.603 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.602 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.602 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.601 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.599 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.598 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.596 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.596 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.590 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.590 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.590 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.588 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.587 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.585 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.585 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.583 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.573 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.565 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.551 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.543 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.531 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.523 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.508 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.506 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.499 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.494 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.489 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.488 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.487 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.485 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.484 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.484 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.483 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.482 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.479 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.479 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.478 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.477 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.476 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.473 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.473 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.472 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.471 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.467 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.466 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.465 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.463 | |
| 1lke | DOG | Bilin-binding protein | / | 0.463 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.463 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 1rxj | BNI | Streptavidin | / | 0.461 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.460 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.459 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.458 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4kmz | FOL | Folate receptor beta | / | 0.458 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.458 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.457 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.456 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.455 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.455 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.455 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.455 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.454 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4phl | PIL | Phosphodiesterase | / | 0.454 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.454 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.453 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.453 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.452 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.451 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.451 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.450 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2xvv | 9DN | Serum albumin | / | 0.450 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.450 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.448 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.448 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.448 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.447 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1syn | F89 | Thymidylate synthase | / | 0.446 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.446 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.446 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3ocx | 2AM | Lipoprotein E | / | 0.446 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.446 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.446 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.444 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.444 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.443 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.443 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.443 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.443 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.442 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.441 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.441 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.441 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.441 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.440 | |
| 2qjp | ANJ | Cytochrome b | / | 0.440 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.440 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.440 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.440 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.440 |