Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qiqCYVReplicase polyprotein 1ab

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2qiqCYVReplicase polyprotein 1ab/1.000
3v3m0ENReplicase polyprotein 1a3.4.19.120.556
2gz8F3FOrf1a polyprotein/0.548
2gz7D3FOrf1a polyprotein/0.514
2op9WR1Orf1ab polyprotein/0.491
2gtbAZPOrf1ab polyprotein/0.452
2a5kAZPReplicase polyprotein 1ab3.4.220.448
2qbuSAHPrecorrin-2 methyltransferase/0.445
5dp2NAPCurF/0.445
3ig6438Urokinase-type plasminogen activator3.4.21.730.441