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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qhxFE1Pteridine reductase 11.5.1.33

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2qhxFE1Pteridine reductase 11.5.1.331.000
2bfaCB3Pteridine reductase 11.5.1.330.700
2bfpH4BPteridine reductase 11.5.1.330.610
1e92HBIPteridine reductase 11.5.1.330.589
3h4vDVPPteridine reductase 11.5.1.330.561
2bf7HBIPteridine reductase 11.5.1.330.541
2bfmTOPPteridine reductase 11.5.1.330.500
3h4vNAPPteridine reductase 11.5.1.330.464
1p33MTXPteridine reductase 11.5.1.330.457