Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q97ATPActin, alpha skeletal muscle

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2q97ATPActin, alpha skeletal muscle/1.000
3m6gATPActin, alpha skeletal muscle/0.583
1lotATPActin, alpha skeletal muscle/0.579
4jhdANPActin-5C/0.576
1rgiATPActin, alpha skeletal muscle/0.574
4k42ADPActin, alpha skeletal muscle/0.574
4pl8ATPActin, alpha skeletal muscle/0.572
3ffkATPActin, alpha skeletal muscle/0.567
2q36ATPActin, alpha skeletal muscle/0.566
5ce3ATPActin/0.564
1t44ATPActin, alpha skeletal muscle/0.562
1qz5ATPActin, alpha skeletal muscle/0.558
4pkhADPActin, alpha skeletal muscle/0.553
4ci6ATPActin/0.545
1h1vATPActin, alpha skeletal muscle/0.543
1mduATPActin, alpha skeletal muscle/0.541
1s22ATPActin, alpha skeletal muscle/0.540
3tu5ATPActin, alpha skeletal muscle/0.539
3mn6ATPActin-5C/0.538
3mn9ATPActin-5C/0.537
4pkgATPActin, alpha skeletal muscle/0.535
1c0fATPMajor actin/0.533
2v51ATPActin, alpha skeletal muscle/0.533
1ijjATPActin, alpha skeletal muscle/0.531
3m1fATPActin, alpha skeletal muscle/0.530
4m63ATPActin-5C/0.523
4pkiATPActin, alpha skeletal muscle/0.520
3a5mATPMajor actin/0.517
1nmdATPMajor actin/0.510
1nm1ATPMajor actin/0.509
3chwATPMajor actin/0.506
4cbxATPActin-2/0.504
1kxpATPActin, alpha skeletal muscle/0.495
4k41ATPActin, alpha skeletal muscle/0.495
3u9dATPActin, alpha skeletal muscle/0.492
1wuaATPActin, alpha skeletal muscle/0.490
3u4lATPActin, cytoplasmic 1/0.488
4rwtANPActin-5C/0.485
1nlvATPMajor actin/0.482
3ekuATPActin-5C/0.472
3w3dATPActin, gamma-enteric smooth muscle/0.470
3dawATPActin, alpha skeletal muscle/0.462
3a5oATPMajor actin/0.459
1yxqATPActin, alpha skeletal muscle/0.452
3el2ATPActin-5C/0.446
1eqyATPActin, alpha skeletal muscle/0.445
4k43ADPActin, alpha skeletal muscle/0.445