sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 1.000 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.490 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 |