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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q4vACODiamine acetyltransferase 22.3.1.57

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2q4vACODiamine acetyltransferase 22.3.1.571.000
2beiACODiamine acetyltransferase 22.3.1.570.623
4r3kCOAN-alpha-acetyltransferase2.3.10.581
3f8kCOAUncharacterized protein/0.547
2x7bCOAN-alpha-acetyltransferase2.3.10.542
4lx9ACON-alpha-acetyltransferase2.3.10.539
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.531
1g67TZPThiamine-phosphate synthase/0.521
5c88COAN-alpha-acetyltransferase/0.520
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.511
4n57ADPAPH(2'')-Id/0.510
3mgdACOPredicted acetyltransferase/0.509
1g6cIFPThiamine-phosphate synthase/0.508
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.508
1n71COAAac(6')-Ii protein/0.505
3pgpACOUncharacterized protein/0.502
4y0xADPSerine/threonine-protein kinase PknG2.7.11.10.501
3u0zCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1/0.496
4riyADPEpidermal growth factor receptor2.7.10.10.496
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.496
5kf9ACOPredicted acetyltransferase/0.496
2qo9ANPEphrin type-A receptor 32.7.10.10.493
2vwu7X1Ephrin type-B receptor 42.7.10.10.493
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.493
1adfTADAlcohol dehydrogenase E chain1.1.1.10.492
2pvyACPFibroblast growth factor receptor 2/0.492
5kf8ACOPredicted acetyltransferase/0.492
2acxANPG protein-coupled receptor kinase 62.7.11.160.491
4fz70VHTyrosine-protein kinase SYK2.7.10.20.491
4fhh0U3Vitamin D3 receptor A/0.490
2qocANPEphrin type-A receptor 32.7.10.10.489
1ir3ANPInsulin receptor2.7.10.10.488
1pxxDIFProstaglandin G/H synthase 21.14.99.10.488
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.488
2rghFADAlpha-Glycerophosphate Oxidase/0.487
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.487
2g37FADProline dehydrogenase/0.485
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.485
4oavACP2-5A-dependent ribonuclease3.1.260.485
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.484
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.484
3s1cZIRCytokinin dehydrogenase 11.5.99.120.484
4gu94GUFocal adhesion kinase 12.7.10.20.484
1g6cTZPThiamine-phosphate synthase/0.483
1pdhFASp-hydroxybenzoate hydroxylase/0.483
3uvp048Mitogen-activated protein kinase 14/0.483
4kubCOAUncharacterized protein/0.483
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.483
5kf2ACOPredicted acetyltransferase/0.483
1g69TZPThiamine-phosphate synthase/0.482
2a4nCOAAac(6')-Ii protein/0.482
3a8tATPAdenylate isopentenyltransferase/0.482
4h9814QUncharacterized protein/0.482
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.482
1db1VDXVitamin D3 receptor/0.481
2henADPEphrin type-B receptor 22.7.10.10.481
3ac1KZITyrosine-protein kinase Lck2.7.10.20.481
3hjaNADGlyceraldehyde-3-phosphate dehydrogenase/0.481
3vt7VDXVitamin D3 receptor/0.481
4cryACOPanD regulatory factor/0.481
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.480
1g4sTPSThiamine-phosphate synthase/0.480
1ie9VDXVitamin D3 receptor/0.480
1lhwESMSex hormone-binding globulin/0.480
2tpsTPSThiamine-phosphate synthase/0.480
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.480
1sn0T44Transthyretin/0.479
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.479
1zrzBI1Protein kinase C iota type2.7.11.130.479
3qdd94MHeat shock protein HSP 90-alpha/0.479
3w0gW07Vitamin D3 receptor/0.479
1kgjFL8Transthyretin/0.478
4cs0ACOPanD regulatory factor/0.478
4eqrFADCoenzyme A disulfide reductase/0.478
4gk3L87Ephrin type-A receptor 32.7.10.10.478
2y6o1N1Ephrin type-A receptor 42.7.10.10.477
3ns2PYVAbscisic acid receptor PYL2/0.477
3sai9DRDihydrofolate reductase/0.477
1drhNAPDihydrofolate reductase1.5.1.30.476
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.476
1uy7PU4Heat shock protein HSP 90-alpha/0.476
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.476
2o7pNAPRiboflavin biosynthesis protein RibD/0.476
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.476
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.476
3vt5YI2Vitamin D3 receptor/0.476
4o1bDGBNicotinamide phosphoribosyltransferase2.4.2.120.476
2ywwATPAspartate carbamoyltransferase regulatory chain/0.475
4xivADPChemotaxis protein CheA2.7.13.30.475
4yswFADXanthine dehydrogenase/oxidase/0.475
1nq24HYThyroid hormone receptor beta/0.474
1txiTX5Vitamin D3 receptor/0.474
3da1FADGlycerol-3-phosphate dehydrogenase/0.474
3uwqU5POrotidine 5'-phosphate decarboxylase/0.474
4ia1BIVVitamin D3 receptor A/0.474
4lb2DM5Serum albumin/0.474
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.473
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.473
2bxmIMNSerum albumin/0.473
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.473
3p8zSAHGenome polyprotein2.1.1.560.473
4b8zNAPGDP-L-fucose synthase1.1.1.2710.473
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.473
4nxvGDPMitochondrial dynamics protein MID51/0.473
4qo9627Serine/threonine-protein kinase 242.7.11.10.473
1bygSTUTyrosine-protein kinase CSK/0.472
1f5fDHTSex hormone-binding globulin/0.472
2vhzNAIAlanine dehydrogenase1.4.1.10.472
3a783EVVitamin D3 receptor/0.472
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.472
3tdwGDPGentamicin resistance protein/0.472
2ep7NADGlyceraldehyde-3-phosphate dehydrogenase/0.471
2rcyNAPPyrroline-5-carboxylate reductase/0.471
3ih0ANPUncharacterized sugar kinase PH14592.7.10.471
3owl19ECasein kinase II subunit alpha2.7.11.10.471
3w0c6DSVitamin D3 receptor/0.471
1r6g442Thyroid hormone receptor beta/0.470
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.470
2hb8MVDVitamin D3 receptor/0.470
2hc4VDXVitamin D3 receptor A/0.470
2itvANPEpidermal growth factor receptor2.7.10.10.470
2j9gANPBiotin carboxylase6.3.4.140.470
3gyaCOAGCN5-related N-acetyltransferase/0.470
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.470
3ttjJBIMitogen-activated protein kinase 102.7.11.240.470
3wowANPCasein kinase II subunit alpha2.7.11.10.470
4ix4ADPUncharacterized protein/0.470
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.470
5dbvCOAAldehyde Dehydrogenase/0.470
5l7dCLRSmoothened homolog/0.470
1g4tFTPThiamine-phosphate synthase/0.469
1l8qADPChromosomal replication initiator protein DnaA/0.469
1m51TSXPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.469
1xe55FEPlasmepsin-23.4.23.390.469
2ituITQEpidermal growth factor receptor2.7.10.10.469
2x1nX1NCyclin-dependent kinase 22.7.11.220.469
3sa16DRDihydrofolate reductase/0.469
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.469
4gteMEFFlavin-dependent thymidylate synthase2.1.1.1480.469
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.469
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.468
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.468
2c27ACOMycothiol acetyltransferase2.3.1.1890.468
3cgdCOACoenzyme A disulfide reductase/0.468
3gwfFADCyclohexanone monooxygenase/0.468
3mvm39PMitogen-activated protein kinase 14/0.468
3w5tLHPVitamin D3 receptor/0.468
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.468
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.468
4iteTEYVitamin D3 receptor/0.468
1ojtFADDihydrolipoyl dehydrogenase/0.467
2rg6287Mitogen-activated protein kinase 14/0.467
2zlcVDXVitamin D3 receptor/0.467
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.467
4dpuAGSMevalonate diphosphate decarboxylase/0.467
4ku5DCC3-oxoacyl-[ACP] synthase III/0.467
4yekTHMThymidine phosphorylase/0.467
5br7FADUDP-galactopyranose mutase/0.467
1osvCHCBile acid receptor/0.466
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.466
3t3r9PLCytochrome P450 2A61.14.130.466
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4g2fC07Ephrin type-A receptor 32.7.10.10.466
4gk4L90Ephrin type-A receptor 32.7.10.10.466
4ia3BIVVitamin D3 receptor A/0.466
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.466
4mxeACON-acetyltransferase ESCO12.3.10.466
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.465
1ol7ADPAurora kinase A2.7.11.10.465
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.465
2pywADPMethylthioribose kinase2.7.1.1000.465
2w1gL0GAurora kinase A2.7.11.10.465
3plsANPMacrophage-stimulating protein receptor2.7.10.10.465
3vjoANPEpidermal growth factor receptor2.7.10.10.465
3vtcTK3Vitamin D3 receptor/0.465
3w0jT08Vitamin D3 receptor/0.465
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.465
4i8vBHFCytochrome P450 1A11.14.14.10.465
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.465
4zhqACPTubulin tyrosine ligase/0.465
1pl8NADSorbitol dehydrogenase1.1.1.140.464
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.464
1rx8NAPDihydrofolate reductase1.5.1.30.464
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.464
2c6dANPAurora kinase A2.7.11.10.464
2cntCOARibosomal-protein-alanine acetyltransferase/0.464
2cy2ACOProbable acetyltransferase/0.464
2hcdBIVVitamin D3 receptor A/0.464
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.464
3nmpPYVAbscisic acid receptor PYL2/0.464
3w5p4OAVitamin D3 receptor/0.464
4c6uTLG3-oxoacyl-ACP synthase/0.464
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.464
4fcwADPChaperone protein ClpB/0.464
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.464
5ap57RODual specificity protein kinase TTK2.7.12.10.464
1s0zEB1Vitamin D3 receptor/0.463
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.463
2izrBRKCasein kinase I isoform gamma-32.7.11.10.463
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.463
3oriAGSSerine/threonine protein kinase/0.463
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.463
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4g1z0VPVitamin D3 receptor A/0.463
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
4hyu1BKMitogen-activated protein kinase 82.7.11.240.463
1g28FMNPHY3/0.462
1i59ANPChemotaxis protein CheA2.7.13.30.462
1nzfUPGDNA beta-glucosyltransferase/0.462
1svlADPLarge T antigen3.6.40.462
1v0oINRCell division control protein 2 homolog2.7.11.220.462
2balPQAMitogen-activated protein kinase 14/0.462
2pzpACPFibroblast growth factor receptor 2/0.462
2z4y252Geranylgeranyl pyrophosphate synthase/0.462
2zbzVDXVitamin D3 dihydroxylase/0.462
2zdt46CMitogen-activated protein kinase 102.7.11.240.462
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.462
3cukFADD-amino-acid oxidase1.4.3.30.462
3dds26BGlycogen phosphorylase, liver form2.4.1.10.462
3frfXCFDihydrofolate reductase1.5.1.30.462
3mqe416Prostaglandin G/H synthase 21.14.99.10.462
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.462
4jxrACOAcetyltransferase/0.462
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.462
4qmlANPSerine/threonine-protein kinase 242.7.11.10.462
4xhgADPUncharacterized protein/0.462
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.462
1ay0TPPTransketolase 12.2.1.10.461
1csnATPCasein kinase I homolog 12.7.11.10.461
1g41ADPATP-dependent protease ATPase subunit HslU/0.461
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1i58ACPChemotaxis protein CheA2.7.13.30.461
1jpaANPEphrin type-B receptor 22.7.10.10.461
1rkhVD2Vitamin D3 receptor/0.461
2hw2RFPRifampin ADP-ribosyl transferase/0.461
2itzIREEpidermal growth factor receptor2.7.10.10.461
2ogiGDPUncharacterized protein/0.461
2p4yC03Peroxisome proliferator-activated receptor gamma/0.461
2wotZZGTGF-beta receptor type-12.7.11.300.461
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.461
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3nxxNDPDihydrofolate reductase1.5.1.30.461
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
3qwbNDPProbable quinone oxidoreductase1.6.5.50.461
3sh25DRDihydrofolate reductase1.5.1.30.461
4aw530KEphrin type-B receptor 42.7.10.10.461
4bqg50QHeat shock protein HSP 90-alpha/0.461
4l78ADPPhosphoribosylformylglycinamidine synthase/0.461
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.461
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.461
1i44ACPInsulin receptor2.7.10.10.460
1ia1NDPDihydrofolate reductase1.5.1.30.460
1ictT44Transthyretin/0.460
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.460
1vyrFMNPentaerythritol tetranitrate reductase/0.460
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2b1pAIZMitogen-activated protein kinase 102.7.11.240.460
2bf7HBIPteridine reductase 11.5.1.330.460
2itqITQEpidermal growth factor receptor2.7.10.10.460
2o4jVD4Vitamin D3 receptor/0.460
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.460
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3ft8MOJHeat shock protein HSP 90-alpha/0.460
3rfxNADUronate dehydrogenase/0.460
3w5rLOAVitamin D3 receptor/0.460
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.460
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1aj22PHDihydropteroate synthase/0.459
1aoeGW3Dihydrofolate reductase1.5.1.30.459
1i59ADPChemotaxis protein CheA2.7.13.30.459
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.459
1rx8FOLDihydrofolate reductase1.5.1.30.459
1upw444Oxysterols receptor LXR-beta/0.459
2b9wFADPutative aminooxidase/0.459
2byh2D7Heat shock protein HSP 90-alpha/0.459
2hk51BMTyrosine-protein kinase HCK2.7.10.20.459
3cgcCOACoenzyme A disulfide reductase/0.459
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.459
3ibqATPPyridoxal kinase/0.459
3igoANPCalmodulin-domain protein kinase 1, putative/0.459
3is2FADVivid PAS protein VVD/0.459
3mpaSB2Mitogen-activated protein kinase 14/0.459
3owj1ELCasein kinase II subunit alpha2.7.11.10.459
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.459
3w0iO11Vitamin D3 receptor/0.459
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.459
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.459
4b8wNAPGDP-L-fucose synthase1.1.1.2710.459
4g2h0VQVitamin D3 receptor A/0.459
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.459
4hjfC2EGGDEF family protein/0.459
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.459
5awmANPStress-activated protein kinase JNK2.7.11.240.459
4k5y1Q5Corticotropin-releasing factor receptor 1/0.459
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.458
1rm3NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.458
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.458
2hasC3OVitamin D3 receptor/0.458
2iw94SPCyclin-dependent kinase 22.7.11.220.458
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.458
2y5s78HDihydropteroate synthase/0.458
2zdu446Mitogen-activated protein kinase 102.7.11.240.458
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.458
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.458
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
3eq1DPMPorphobilinogen deaminase2.5.1.610.458
3ez2ADPPlasmid partition protein A/0.458
3n6mGTPGenome polyprotein/0.458
3nj0PYVAbscisic acid receptor PYL2/0.458
3uozNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.458
4e730NRMitogen-activated protein kinase 82.7.11.240.458
4fhi0S4Vitamin D3 receptor A/0.458
4qms1N1Serine/threonine-protein kinase 242.7.11.10.458
4rujVDXVitamin D3 receptor A/0.458
4uxxACPDiacylglycerol kinase2.7.1.1070.458
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1h51FMNPentaerythritol tetranitrate reductase/0.457
1q4xG24Thyroid hormone receptor beta/0.457
2dbqNAPGlyoxylate reductase1.1.1.260.457
2pknACPAdenosine kinase2.7.1.200.457
2wo7ASVIsopenicillin N synthase1.21.3.10.457
3datMTXDihydrofolate reductase/0.457
3dr1C5DVitamin D3 receptor A/0.457
3g51ANPRibosomal protein S6 kinase alpha-32.7.11.10.457
3ijdC2FMethylenetetrahydrofolate reductase/0.457
3w0hW12Vitamin D3 receptor/0.457
3w16P9JAurora kinase A2.7.11.10.457
4avaACOAcetyltransferase Pat2.3.10.457
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.457
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.457
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.457
5dt4ATPAurora kinase A2.7.11.10.457
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1qxoFMNChorismate synthase/0.456
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
2cyeCOAPutative thioesterase/0.456
2d8aNADL-threonine 3-dehydrogenase/0.456
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.456
2iw84SPCyclin-dependent kinase 22.7.11.220.456
2of4979Tyrosine-protein kinase Lck2.7.10.20.456
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.456
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.456
2zuiCAMCamphor 5-monooxygenase1.14.15.10.456
3eek53SUncharacterized protein/0.456
3tdvGDPGentamicin resistance protein/0.456
3vrwYS5Vitamin D3 receptor/0.456
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.456
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.456
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.456
4l8u9AZSerum albumin/0.456
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.456
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
5cccDDFDihydrofolate reductase1.5.1.30.456
1jq5NADGlycerol dehydrogenase1.1.1.60.455
1ykdCMPAdenylate cyclase/0.455
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2hb7O1CVitamin D3 receptor/0.455
2itnANPEpidermal growth factor receptor2.7.10.10.455
2p3qSAHGenome polyprotein/0.455
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
2vgoAD5Aurora kinase B-A2.7.11.10.455
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.455
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.455
3tjsD0RCytochrome P450 3A4/0.455
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.455
3zqtTESAndrogen receptor/0.455
4c3rACPAurora kinase A2.7.11.10.455
4du82P0Mevalonate diphosphate decarboxylase/0.455
4eor4SPCyclin-dependent kinase 22.7.11.220.455
4g2i0VQVitamin D3 receptor/0.455
4hgt15GCasein kinase I isoform delta2.7.11.10.455
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.455
4nm5ADPGlycogen synthase kinase-3 beta2.7.11.260.455
4oadCLMUncharacterized protein/0.455
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.455
5cvcPLPSerine racemase/0.455
5idwNAPShort-chain dehydrogenase/reductase SDR/0.455
1fq1ATPCyclin-dependent kinase 22.7.11.220.454
1ie8KH1Vitamin D3 receptor/0.454
1jscTPPAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.454
1nqaNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.454
1s19MC9Vitamin D3 receptor/0.454
2bycFMNBlue-light receptor of the BLUF-family/0.454
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2hamC33Vitamin D3 receptor/0.454
3eigMTXDihydrofolate reductase1.5.1.30.454
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.454
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.454
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.454
3sfuRBVPolyprotein/0.454
3vt9YI4Vitamin D3 receptor/0.454
3w0aDS5Vitamin D3 receptor/0.454
4dx7DM2Multidrug efflux pump subunit AcrB/0.454
4f700STCyclin-dependent kinase 82.7.11.220.454
4g1d0VKVitamin D3 receptor A/0.454
4g8zTOPDihydrofolate reductase1.5.1.30.454
4hlwTESAndrogen receptor/0.454
4r87COASpermidine N(1)-acetyltransferase/0.454
1a72PADAlcohol dehydrogenase E chain1.1.1.10.453
1e0aGNPCell division control protein 42 homolog/0.453
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1rx3MTXDihydrofolate reductase1.5.1.30.453
2bunFADAppA protein/0.453
2bx8AZQSerum albumin/0.453
2dfvNADL-threonine 3-dehydrogenase/0.453
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.453
2itwITQEpidermal growth factor receptor2.7.10.10.453
2qoqANPEphrin type-A receptor 32.7.10.10.453
2xdrNDPNAD/NADP-dependent betaine aldehyde dehydrogenase/0.453
2xgoZKDUncharacterized protein/0.453
3q9zTXQCasein kinase II subunit alpha2.7.11.10.453
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.453
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.453
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.453
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.453
4m2xTMQDihydrofolate reductase1.5.1.30.453
4mgiCMPRap guanine nucleotide exchange factor 4/0.453
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.453
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.452
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.452
1txtCAAHMG-CoA synthase/0.452
2e9zUTPGenome polyprotein/0.452
2hog710Serine/threonine-protein kinase Chk12.7.11.10.452
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.452
2o4rVD5Vitamin D3 receptor/0.452
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.452
2w6nOA2Biotin carboxylase6.3.4.140.452
2yyuC5POrotidine 5'-phosphate decarboxylase/0.452
2zl9VDAVitamin D3 receptor/0.452
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.452
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.452
3evbSAHGenome polyprotein2.1.1.560.452
3ge1ADPGlycerol kinase/0.452
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3jpuTY4Transcriptional activator protein LasR/0.452
3jziJZLBiotin carboxylase6.3.4.140.452
3k1jADPATP-dependent protease Lon/0.452
3l8p0CEAngiopoietin-1 receptor2.7.10.10.452
3nszANPCasein kinase II subunit alpha2.7.11.10.452
3v1yNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.452
3zkyWT4Isopenicillin N synthase1.21.3.10.452
4bcoT6QCyclin-dependent kinase 22.7.11.220.452
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.452
4kb81QOCasein kinase I isoform delta2.7.11.10.452
4ki8ADP60 kDa chaperonin/0.452
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.452
4mgkCMPRap guanine nucleotide exchange factor 4/0.452
4mv8ACPBiotin carboxylase6.3.4.140.452
4nm9FADBifunctional protein PutA/0.452
4wkqIREEpidermal growth factor receptor2.7.10.10.452
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.452
1b87ACOAac(6')-Ii protein/0.451
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.451
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.451
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.451
1u54ACPActivated CDC42 kinase 1/0.451
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.451
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.451
1wlvCOAPhenylacetic acid degradation protein PaaI/0.451
2excJNKMitogen-activated protein kinase 102.7.11.240.451
2gs7ANPEpidermal growth factor receptor2.7.10.10.451
2uyiADPKinesin-like protein KIF11/0.451
2vd5BI8Myotonin-protein kinase2.7.11.10.451
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.451
3lu8IQXSerum albumin/0.451
3mdvCL6Cholesterol 24-hydroxylase/0.451
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3och2MXDihydrofolate reductase1.5.1.30.451
3oibFDAPutative acyl-CoA dehydrogenase/0.451
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.451
3vruYS3Vitamin D3 receptor/0.451
3vs3VSETyrosine-protein kinase HCK2.7.10.20.451
3vt8YI3Vitamin D3 receptor/0.451
4cukNAID-lactate dehydrogenase/0.451
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.451
4iebANPCalmodulin-domain protein kinase 1/0.451
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.451
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1di8DTQCyclin-dependent kinase 22.7.11.220.450
1fmlRTLRetinol dehydratase/0.450
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.450
1lp4ANPCasein kinase II subunit alpha2.7.11.10.450
1olsTDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.450
1qaxHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.450
1rkgVD1Vitamin D3 receptor/0.450
1xjjDGTVitamin B12-dependent ribonucleotide reductase/0.450
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.450
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2o12FMNChorismate synthase/0.450
2rc6NAPFerredoxin--NADP reductase/0.450
2wihP48Cyclin-dependent kinase 22.7.11.220.450
2x4f16XMyosin light chain kinase family member 42.7.11.10.450
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.450
2zjwREFCasein kinase II subunit alpha2.7.11.10.450
3cseN22Uncharacterized protein/0.450
3fhyATPPyridoxal kinase2.7.1.350.450
3hk1B64Fatty acid-binding protein, adipocyte/0.450
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.450
3vtdTKDVitamin D3 receptor/0.450
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.450
4bfxZVXPantothenate kinase2.7.1.330.450
4c4g7RODual specificity protein kinase TTK2.7.12.10.450
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.450
4dptAGSMevalonate diphosphate decarboxylase/0.450
4e03ADPPlasmid partitioning protein ParF/0.450
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.450
4in44IDKelch-like ECH-associated protein 1/0.450
4k33ACPFibroblast growth factor receptor 32.7.10.10.450
4o1pANPRibonuclease L/0.450
4pytFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.450
4q0a4OAVitamin D3 receptor A/0.450
4rupH97Vitamin D3 receptor A/0.450
4tuvCPZCytochrome P450 1191.140.450
4zohFADPutative oxidoreductase FAD-binding subunit/0.450
1d2sDHTSex hormone-binding globulin/0.449
1j39UPGDNA beta-glucosyltransferase/0.449
1njfAGSDNA polymerase III subunit tau2.7.7.70.449
1ozhHE3Acetolactate synthase, catabolic2.2.1.60.449
1rkdADPRibokinase/0.449
1s3vTQDDihydrofolate reductase1.5.1.30.449
2c96ATPPsp operon transcriptional activator/0.449
2cchATPCyclin-dependent kinase 22.7.11.220.449
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.449
2ghmLICMitogen-activated protein kinase 14/0.449
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.449
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.449
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.449
2rhrEMOPutative ketoacyl reductase1.3.10.449
2vwx7X4Ephrin type-B receptor 42.7.10.10.449
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.449
3cmcNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.449
3gviADPMalate dehydrogenase/0.449
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.449
4eomATPCyclin-dependent kinase 22.7.11.220.449
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.449
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.449
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.449
5cu6ATPCasein kinase II subunit alpha2.7.11.10.449
1d7lRFLp-hydroxybenzoate hydroxylase/0.448
1m4dCOAAminoglycoside 2'-N-acetyltransferase2.3.10.448
1n9nFMNPutative blue light receptor/0.448
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1qayMEV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.448
1rjkVDZVitamin D3 receptor/0.448
2a1uFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.448
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2dbzNAPGlyoxylate reductase1.1.1.260.448
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.448
2nq8ZIDEnoyl-ACP reductase/0.448
2puiADPMethylthioribose kinase2.7.1.1000.448
2vbpVB1Isopenicillin N synthase1.21.3.10.448
2yee2ECHeat shock protein HSP 90-alpha/0.448
3bqcEMOCasein kinase II subunit alpha2.7.11.10.448
3ddpRC8Cyclin-dependent kinase 22.7.11.220.448
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3ingNDPHomoserine dehydrogenase related protein/0.448
3of4FMNNitroreductase/0.448
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3vt65YIVitamin D3 receptor/0.448
3w5q3KLVitamin D3 receptor/0.448
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
4coxIMNProstaglandin G/H synthase 21.14.99.10.448
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.448
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.448
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.448
4kos4KOUncharacterized protein/0.448
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.448
4z0pNDPNAD-dependent dehydrogenase/0.448
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.448
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1cbsREACellular retinoic acid-binding protein 2/0.447
1dhrNADDihydropteridine reductase1.5.1.340.447
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1e9hINRCyclin-dependent kinase 22.7.11.220.447
1efpFADElectron transfer flavoprotein subunit alpha/0.447
1hk4T44Serum albumin/0.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1tdrMTXDihydrofolate reductase1.5.1.30.447
1uy9PU6Heat shock protein HSP 90-alpha/0.447
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.447
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.447
2h94FADLysine-specific histone demethylase 1A10.447
2izsBRQCasein kinase I isoform gamma-32.7.11.10.447
2py3ACPFibroblast growth factor receptor 2/0.447
2q6cHR13-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.447
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2vzzSCAPutative succinyl-CoA transferase Rv0802c2.8.30.447
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.447
2z6jTUI2-nitropropane dioxygenase/0.447
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.447
3ddw055Glycogen phosphorylase, liver form2.4.1.10.447
3icrCOACoenzyme A disulfide reductase/0.447
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.447
3k8tDGTRibonucleoside-diphosphate reductase large chain 11.17.4.10.447
3mdmFJZCholesterol 24-hydroxylase/0.447
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.447
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.447
3sjzGNPTranslation initiation factor 2 subunit gamma/0.447
3u9eCOALmo1369 protein/0.447
3up0D7SaceDAF-12/0.447
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.447
3vt3VDXVitamin D3 receptor/0.447
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.447
4c02TAKActivin receptor type-12.7.11.300.447
4ceaZSWIntegrase/0.447
4e5pNADPhosphonate dehydrogenase1.20.1.10.447
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4ie5MD6Alpha-ketoglutarate-dependent dioxygenase FTO/0.447
4jbqVX6Aurora kinase A2.7.11.10.447
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
1c1dNAIPhenylalanine dehydrogenase/0.446
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.446
1juvNDPDihydrofolate reductase1.5.1.30.446
1opbRETRetinol-binding protein 2/0.446
1wygFADXanthine dehydrogenase/oxidase/0.446
1x2hLPALipoate-protein ligase A6.3.1.200.446
1yw2PGJMitogen-activated protein kinase 14/0.446
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
2baqPQBMitogen-activated protein kinase 14/0.446
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.446
2fzkCTPAspartate carbamoyltransferase regulatory chain/0.446
2nliFMNLactate oxidase/0.446
2pz5ACPFibroblast growth factor receptor 2/0.446
2q61SF1Peroxisome proliferator-activated receptor gamma/0.446
2xvdAS6Ephrin type-B receptor 42.7.10.10.446
2z97CAMCamphor 5-monooxygenase1.14.15.10.446
3csdEMOPutative ketoacyl reductase1.3.10.446
3eej53RUncharacterized protein/0.446
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3h4vDVPPteridine reductase 11.5.1.330.446
3kpzZNEVitamin D3 receptor/0.446
3mtfA3FActivin receptor type-12.7.11.300.446
3nf7CIWGag-Pol polyprotein/0.446
3njoP2MAbscisic acid receptor PYR1/0.446
3r1kCOAN-acetyltransferase Eis/0.446
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.446
3ruqADPChaperonin/0.446
3rvg17PTyrosine-protein kinase JAK2/0.446
3w9rA8SAbscisic acid receptor PYL9/0.446
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.446
4bb432WEphrin type-B receptor 42.7.10.10.446
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.446
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4giu636Anthranilate phosphoribosyltransferase/0.446
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.446
4i6gFADCryptochrome-2/0.446
4itfTFYVitamin D3 receptor/0.446
4jq8KJ8Epidermal growth factor receptor2.7.10.10.446
4k6fNAPPutative Acetoacetyl-CoA reductase/0.446
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.446
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.446
4nmdFDABifunctional protein PutA/0.446
5dt3ATPAurora kinase A2.7.11.10.446
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
5ikqJMSProstaglandin G/H synthase 21.14.99.10.446
5im3DTPRibonucleoside-diphosphate reductase/0.446
1dawANPCasein kinase II subunit alpha2.7.11.10.445
1h1s4SPCyclin-dependent kinase 22.7.11.220.445
1jutLYDThymidylate synthase/0.445
1kzkJE2Gag-Pol polyprotein3.4.23.160.445
1lhvNOGSex hormone-binding globulin/0.445
1ml6GBXGlutathione S-transferase A22.5.1.180.445
1nhhANPDNA mismatch repair protein MutL/0.445
1omoNADAlanine dehydrogenase/0.445
1pjkANPCasein kinase II subunit alpha2.7.11.10.445
1qjfACSIsopenicillin N synthase1.21.3.10.445
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.445
1w49APCNTPase P4/0.445
2dcnADP2-keto-3-deoxy-gluconate kinase/0.445
2fj1CTCTetracycline repressor protein class D/0.445
2harOCCVitamin D3 receptor/0.445
2oz6CMPCyclic AMP receptor-like protein/0.445
2wqeADPAurora kinase A2.7.11.10.445
2xvw9NRSerum albumin/0.445
3cgbCOACoenzyme A disulfide reductase/0.445
3nfaCBJGag-Pol polyprotein/0.445
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.445
3repATPIntegrin-linked protein kinase2.7.11.10.445
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4cfaWOPIntegrase/0.445
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.445
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.445
4e2bFMNDehydrogenase/0.445
4egiB2JHeat shock protein HSP 90-alpha/0.445
4ejmNAPPutative zinc-binding dehydrogenase/0.445
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.445
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4hwkNAPSepiapterin reductase1.1.1.1530.445
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4rrxLURProstaglandin G/H synthase 21.14.99.10.445
4ruoBIVVitamin D3 receptor A/0.445
5eccNAPDehydrofolate reductase type I/0.445
1h5tTYDGlucose-1-phosphate thymidylyltransferase 1/0.444
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
1nsfATPVesicle-fusing ATPase3.6.4.60.444
1o6kANPRAC-beta serine/threonine-protein kinase2.7.11.10.444
1qmfKEFPenicillin-binding protein 2x/0.444
1qz5ATPActin, alpha skeletal muscle/0.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.444
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.444
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.444
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.444
2o2yTCLEnoyl-ACP reductase/0.444
2qpyDHTAndrogen receptor/0.444
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.444
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.444
2xp2VGHALK tyrosine kinase receptor2.7.10.10.444
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.444
3a3gDLZLumazine protein/0.444
3at3ATKCasein kinase II subunit alpha2.7.11.10.444
3atyFMNProstaglandin F2a synthase/0.444
3cgeNDPCoenzyme A disulfide reductase/0.444
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.444
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3icsADPCoenzyme A disulfide reductase/0.444
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.444
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.444
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.444
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.444
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4anqVGHALK tyrosine kinase receptor2.7.10.10.444
4b99R4LMitogen-activated protein kinase 72.7.11.240.444
4gyiADPUncharacterized protein/0.444
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.444
4iaq2GM5-hydroxytryptamine receptor 1B/0.444
4jqlVJ6Heat shock protein HSP 90-alpha/0.444
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.444
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.444
4qosADPPsp operon transcriptional activator/0.444
4utdACPAurora kinase A2.7.11.10.444
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.444
1b15NAEAlcohol dehydrogenase1.1.1.10.443
1e92HBIPteridine reductase 11.5.1.330.443
1eqyATPActin, alpha skeletal muscle/0.443
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1gjrNAPFerredoxin--NADP reductase1.18.1.20.443
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.443
1l9kSAHGenome polyprotein2.7.7.480.443
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.443
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.443
1qsmACOHistone acetyltransferase HPA2/0.443
1rx1NAPDihydrofolate reductase1.5.1.30.443
1sg6NADPentafunctional AROM polypeptide/0.443
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.443
2bfpH4BPteridine reductase 11.5.1.330.443
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.443
2fy4COACholine O-acetyltransferase2.3.1.60.443
2jjkR15Fructose-1,6-bisphosphatase 13.1.3.110.443
2p33J07Mitogen-activated protein kinase 102.7.11.240.443
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.443
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.443
2zbaZBATrichothecene 3-O-acetyltransferase/0.443
3a20FMNFMN-binding protein/0.443
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.443
3d7tSTUTyrosine-protein kinase CSK/0.443
3ef5DGTProbable pyrophosphohydrolase/0.443
3gxlQIGTGF-beta receptor type-12.7.11.300.443
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.443
3o153NMThiamine-phosphate synthase/0.443
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
3tqhNDPQuinone oxidoreductase/0.443
3vglANPGlucokinase/0.443
3vjnANPEpidermal growth factor receptor2.7.10.10.443
3w0qANPHygromycin-B 4-O-kinase2.7.1.1630.443
3w0yDS4Vitamin D3 receptor/0.443
3wv9FEGHmd co-occurring protein HcgE/0.443
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.443
4c4h7RODual specificity protein kinase TTK2.7.12.10.443
4eftEFTHeat shock protein HSP 90-alpha/0.443
4ejgNCTCytochrome P450 2A131.14.14.10.443
4eji0QACytochrome P450 2A131.14.14.10.443
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.443
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.443
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4ogrADNCyclin-dependent kinase 92.7.11.220.443
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.443
4y3jHICEndothiapepsin3.4.23.220.443
4ybrNAPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.443
1cqp803Integrin alpha-L/0.442
1e26GPBDihydrofolate reductase1.5.1.30.442
1e3eNAIAlcohol dehydrogenase 41.1.1.10.442
1h72ANPHomoserine kinase2.7.1.390.442
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.442
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.442
1nq7ARLNuclear receptor ROR-beta/0.442
1ol6ATPAurora kinase A2.7.11.10.442
1p0hACOMycothiol acetyltransferase2.3.1.1890.442
1phhFADp-hydroxybenzoate hydroxylase/0.442
1sn5T3Transthyretin/0.442
2bbqPFGThymidylate synthase/0.442
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.442
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
2vhvNAIAlanine dehydrogenase1.4.1.10.442
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.442
2wipP49Cyclin-dependent kinase 22.7.11.220.442
2xuuADPDeath-associated protein kinase 12.7.11.10.442
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.442
3f3sNADLambda-crystallin homolog/0.442
3nwyGTPUridylate kinase/0.442
3oquA8SAbscisic acid receptor PYL9/0.442
3pj8404Cyclin-dependent kinase 22.7.11.220.442
3pnlADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.442
3vrvYSDVitamin D3 receptor/0.442
4foxUMPThymidylate synthase ThyA/0.442
4i22IREEpidermal growth factor receptor2.7.10.10.442
4iskUMPThymidylate synthase/0.442
4j6dTESCytochrome P450 monooxygenase/0.442
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.442
4o2bLOCTubulin beta-2B chain/0.442
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.442
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.442
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.442
4xldBRLPeroxisome proliferator-activated receptor gamma/0.442
4z69DIFSerum albumin/0.442
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.442
5dn3ATPAurora kinase A2.7.11.10.442
5iqhGNPBifunctional AAC/APH2.3.10.442
1bpwNADBetaine aldehyde dehydrogenase1.2.1.80.441
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
1di9MSQMitogen-activated protein kinase 14/0.441
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.441
1h65GDPTranslocase of chloroplast 343.6.50.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1kifFADD-amino-acid oxidase1.4.3.30.441
1m17AQ4Epidermal growth factor receptor2.7.10.10.441
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
1powFADPyruvate oxidase1.2.3.30.441
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.441
1zz2B11Mitogen-activated protein kinase 14/0.441
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.441
2c3qGTXGlutathione S-transferase theta-12.5.1.180.441
2hayFMNPutative NAD(P)H-flavin oxidoreductase/0.441
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.441
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.441
2npnSAMPutative cobalamin synthesis related protein/0.441
2r9eSDXCitrate synthase2.3.3.160.441
2zxuDSTtRNA dimethylallyltransferase2.5.1.750.441
2zzaFOLDihydrofolate reductase/0.441
3be9P04Casein kinase II subunit alpha2.7.11.10.441
3bqr4RBDeath-associated protein kinase 3/0.441
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.441
3hdyFADUDP-galactopyranose mutase/0.441
3icsCOACoenzyme A disulfide reductase/0.441
3iw4LW4Protein kinase C alpha type2.7.11.130.441
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.441
3sruQ26Dihydrofolate reductase1.5.1.30.441
3ta2ATPNitrogen regulatory protein P-II (GlnB-3)/0.441
3ub5ATPActin, cytoplasmic 1/0.441
3vrtYS2Vitamin D3 receptor/0.441
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.441
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.441
4ajo88NL-lactate dehydrogenase A chain1.1.1.270.441
4awp99AHeat shock protein HSP 90-alpha/0.441
4cvlACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.441
4dpy2P0Mevalonate diphosphate decarboxylase/0.441
4eh3NARMitogen-activated protein kinase 14/0.441
4fgh0U6Dihydrofolate reductase1.5.1.30.441
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4hjoAQ4Epidermal growth factor receptor2.7.10.10.441
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.441
4jrnANPRhoptry kinase family protein/0.441
4jy2FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.441
4kbk1QGCasein kinase I isoform delta2.7.11.10.441
4prvADPDNA gyrase subunit B/0.441
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.441
4yaf2AMNADPH--cytochrome P450 reductase/0.441
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.440
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.440
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.440
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.440
1naxIH5Thyroid hormone receptor beta/0.440
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1nytNAPShikimate dehydrogenase (NADP(+))/0.440
1um8ADPATP-dependent Clp protease ATP-binding subunit ClpX/0.440
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.440
1v9aSAHUncharacterized protein/0.440
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.440
2bxaC1FSerum albumin/0.440
2cbsR13Cellular retinoic acid-binding protein 2/0.440
2cnsACORibosomal-protein-alanine acetyltransferase/0.440
2eklNADD-3-phosphoglycerate dehydrogenase/0.440
2hckQUETyrosine-protein kinase HCK2.7.10.20.440
2jkkBI9Focal adhesion kinase 12.7.10.20.440
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.440
2oxtSAMGenome polyprotein/0.440
2pg0FADAcyl-CoA dehydrogenase/0.440
2pkrNDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.440
2pwcG3GGag-Pol polyprotein3.4.23.160.440
2rkvZBATrichothecene 3-O-acetyltransferase/0.440
2vcmM11Isopenicillin N synthase1.21.3.10.440
2vnjFADNADPH:ferredoxin reductase/0.440
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.440
3d0bSNXHeat shock protein HSP 90-alpha/0.440
3dogNNNCyclin-dependent kinase 22.7.11.220.440
3gqvNAPEnoyl reductase LovC10.440
3h4vNAPPteridine reductase 11.5.1.330.440
3ig8ADPGlutamate--cysteine ligase6.3.2.20.440
3k5uPFQAurora kinase A2.7.11.10.440
3k6l2BBPeptide deformylase3.5.1.880.440
3orlAGSSerine/threonine protein kinase/0.440
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.440
3r7eX88Cyclin-dependent kinase 22.7.11.220.440
3rinI2OMitogen-activated protein kinase 14/0.440
3s1dZIRCytokinin dehydrogenase 11.5.99.120.440
3sa27DRDihydrofolate reductase/0.440
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.440
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.440
3vtbTKAVitamin D3 receptor/0.440
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
3znpFADD-amino-acid oxidase1.4.3.30.440
3zsxN44Integrase/0.440
3zvuA8SAbscisic acid receptor PYR1/0.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.440
4bchT7ZCyclin-dependent kinase 92.7.11.220.440
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.440
4bn1ADPAurora kinase A2.7.11.10.440
4bzqADPBifunctional enzyme CysN/CysC2.7.1.250.440
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.440
4hhdFMNPhototropin-12.7.11.10.440
4ix5ANPUncharacterized protein/0.440
4ixd1HVIntegrin alpha-L/0.440
4izy1J2Mitogen-activated protein kinase 82.7.11.240.440
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.440
4k2rANPTyrosine-protein kinase ZAP-702.7.10.20.440
4kl9NDPDihydrofolate reductase1.5.1.30.440
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4oplFDAConserved Archaeal protein/0.440
4u0mGTPCyclic GMP-AMP synthase/0.440
4xg1LLPDiaminopimelate decarboxylase/0.440
4xivACPChemotaxis protein CheA2.7.13.30.440
4xlvACPInsulin receptor2.7.10.10.440
5cvhADPCasein kinase II subunit alpha2.7.11.10.440
5l8kADPAurora kinase A2.7.11.10.440