Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q36ATPActin, alpha skeletal muscle

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2q36ATPActin, alpha skeletal muscle/1.000
1qz5ATPActin, alpha skeletal muscle/0.576
4k42ADPActin, alpha skeletal muscle/0.574
1c0fATPMajor actin/0.561
3m6gATPActin, alpha skeletal muscle/0.561
4pl8ATPActin, alpha skeletal muscle/0.560
1h1vATPActin, alpha skeletal muscle/0.558
1mduATPActin, alpha skeletal muscle/0.558
1rgiATPActin, alpha skeletal muscle/0.555
4cbxATPActin-2/0.554
1s22ATPActin, alpha skeletal muscle/0.547
3m1fATPActin, alpha skeletal muscle/0.545
3mn6ATPActin-5C/0.541
5ce3ATPActin/0.539
4pkhADPActin, alpha skeletal muscle/0.537
4pkgATPActin, alpha skeletal muscle/0.536
4pkiATPActin, alpha skeletal muscle/0.534
1t44ATPActin, alpha skeletal muscle/0.528
3u9dATPActin, alpha skeletal muscle/0.528
4jhdANPActin-5C/0.527
1lotATPActin, alpha skeletal muscle/0.526
3ffkATPActin, alpha skeletal muscle/0.524
1nmdATPMajor actin/0.523
3tu5ATPActin, alpha skeletal muscle/0.520
2v51ATPActin, alpha skeletal muscle/0.515
3mn9ATPActin-5C/0.515
1kxpATPActin, alpha skeletal muscle/0.506
1ijjATPActin, alpha skeletal muscle/0.505
4rwtANPActin-5C/0.502
2q97ATPActin, alpha skeletal muscle/0.490
3w3dATPActin, gamma-enteric smooth muscle/0.478
4m63ATPActin-5C/0.478
1nm1ATPMajor actin/0.469
3a5mATPMajor actin/0.468
3chwATPMajor actin/0.466
3u4lATPActin, cytoplasmic 1/0.461
4ci6ATPActin/0.457
1nlvATPMajor actin/0.451
3a5oATPMajor actin/0.451
1wuaATPActin, alpha skeletal muscle/0.450
2a41ATPActin, alpha skeletal muscle/0.449