sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q2z | MKK | Kinesin-like protein KIF11 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2q2z | MKK | Kinesin-like protein KIF11 | / | 1.000 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.623 | |
| 1q0b | NAT | Kinesin-like protein KIF11 | / | 0.622 | |
| 2g1q | N9H | Kinesin-like protein KIF11 | / | 0.609 | |
| 2x7d | EGB | Kinesin-like protein KIF11 | / | 0.578 | |
| 1x88 | NAT | Kinesin-like protein KIF11 | / | 0.577 | |
| 2wog | ZZD | Kinesin-like protein KIF11 | / | 0.575 | |
| 2fme | 3QC | Kinesin-like protein KIF11 | / | 0.565 | |
| 3k3b | L31 | Kinesin-like protein KIF11 | / | 0.562 | |
| 4bbg | V02 | Kinesin-like protein KIF11 | / | 0.558 | |
| 2gm1 | 2AZ | Kinesin-like protein KIF11 | / | 0.552 | |
| 2x7e | X7E | Kinesin-like protein KIF11 | / | 0.552 | |
| 2ieh | MOY | Kinesin-like protein KIF11 | / | 0.547 | |
| 3ken | ZZD | Kinesin-like protein KIF11 | / | 0.539 | |
| 3k5e | K5E | Kinesin-like protein KIF11 | / | 0.538 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.531 | |
| 2xae | 2XA | Kinesin-like protein KIF11 | / | 0.526 | |
| 4a5y | G7X | Kinesin-like protein KIF11 | / | 0.523 | |
| 2x7c | KZ9 | Kinesin-like protein KIF11 | / | 0.521 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.492 | |
| 2yy8 | MTA | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.461 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.460 | |
| 4iay | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.458 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.457 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.454 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.451 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.450 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.448 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.448 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.448 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.446 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.446 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.446 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.446 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.445 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 3eb0 | DRK | Uncharacterized protein | / | 0.443 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2zxu | DST | tRNA dimethylallyltransferase | 2.5.1.75 | 0.441 | |
| 3u9e | COA | Lmo1369 protein | / | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 |