Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2q1l | 882 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
2q1l | 882 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 1.000 | |
2r4f | RIE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.610 | |
1hw8 | ADP | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.573 | |
1hwj | ADP | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.548 | |
1dq8 | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.518 |