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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2px2SAHGenome polyprotein2.7.7.48

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2px2SAHGenome polyprotein2.7.7.481.000
2px5SAHGenome polyprotein2.7.7.480.615
3evcSAHGenome polyprotein2.1.1.560.589
2pxaSAHGenome polyprotein2.7.7.480.550
5jjrSAHGenome polyprotein/0.538
3eluSAMMethyltransferase/0.535
4ctkSAMGenome polyprotein/0.532
3lkzSFGGenome polyprotein/0.530
4k6mSAHGenome polyprotein/0.509
3p8zSAHGenome polyprotein2.1.1.560.506
3eldSFGMethyltransferase/0.501
3elySAHMethyltransferase/0.498
2oxtSAMGenome polyprotein/0.495
4ctjSAMGenome polyprotein/0.494
2p41SAHGenome polyprotein/0.470
2xbmSAHGenome polyprotein/0.459
3p97SAMGenome polyprotein2.1.1.560.458
3p8z36AGenome polyprotein2.1.1.560.457
5jjsSAHGenome polyprotein/0.452